查询词典 neuronal

Objective:To explore the relation of delayed neuronal death with neuronal apoptosis following transient forebrain ischemia in the gerbil.

目的：探讨脑缺血再灌后迟发性神经元死亡与细胞凋亡的关系。

Muscle type AchR is an important medium of neuronal transmission and main immunogen of Myasthenia gravis,as well as some diseases were induced by the mutation of neuronal\|typed AchR.

肌肉型乙酰胆碱受体是肌肉神经传导中的重要媒介物质以及自身免疫疾病重症肌无力的主要免疫原，神经型乙酰胆碱受体的突变也可导致某些疾病的发生。

The pathologic phenotype in all cases has thus far included ubiquitinated neuronal intranuclear inclusions and neuronal cytoplasmic inclusions.

其病理表现包括泛素化的神经元的核内包涵体和神经元的胞浆包涵体。

The table of contents include 15 parts, early events in neural development; neuronal differentiation; pattern and positional information; movement and migration of neurons; axon outgrowth and the generation of stereotyped nerve patterns; neuronal death during development; trophic effects of targets on neurons; long-term effects of neurons on their targets; formation of synapses; selective synaptic connections; the molecular basis of neuronal recognition; rearrangement of developing neuronal connections; maintenance and modifiability of synapses; the development of behavior; principles of neural development.

内容包括15部分，早期神经发育事件；神经细胞分化；模式与位置信息；神经元运动及迁移；轴突生长与固定的神经模式的形成；发育过程中的神经细胞死亡；对神经细胞靶向的营养效应；神经细胞对它们靶向的长期效应；突触形成；选择突触连结；神经细胞识别的分子基础；发育过程中神经细胞连结的重置；突触保持和改变；行为发育；神经发育原理。

Ultimately, vulnerable groups of neurons atrophy and die in a process that may involve excitotoxicity (overstimulation of neurotransmitter receptors on neuronal surface membranes), collapse of calcium homeostasis, inflammation, and depletion of energy and growth factors. A form of apolipoprotein E, apoE4, contributes to the abnormal accumulation of A and tau, but probably also damages mitochondria and the cellular cytoskeleton. A , tau, apoE and -synuclein interact with many other molecules and modulate diverse signalling cascades that regulate neuronal activity and survival.

最后，易感神经元会萎缩直至死亡，原因可能有兴奋性中毒（神经递质对神经元表面受体的过度刺激引起），钙稳态失衡，炎症反应，能量和生长因子的耗尽。apoE4的产生可导致A肽和tau蛋白的异常聚合，可能也损害线粒体和细胞骨架。A肽、tau蛋白、apoE和突触核蛋白可与很多分子反应，也可调节不同信号级联反应，这些级联反应对于维持神经元活动性和生存性意义重大。

The present work was therefore designed to record single unit discharging from afferent fibers of DRG neuron, collect the interspike interval sequence of neuronal discharges, sum and analyze the rhythmic pattern of neuronal discharges, and finally perfuse the injured DRG neuron with different potassium channel blockers in order to identify the underlying dynamic rules of variations in the rhythmic patterns of neuronal discharges.

本研究从损伤DRG传入纤维中引导单根神经纤维放电，采集神经纤维放电的动作电位间期interspike interval，ISI）序列。归纳和分析神经元放电的节律形式，应用不同〓通道阻断剂灌流损伤DRG，观察神经元放电节律变化的动力学规律。主要结果如下

The present work was therefore designed to record single unit discharging from afferent fibers of DRG neuron, collect the interspike interval sequence of neuronal discharges, sum and analyze, the rhythmic pattern of neuronal discharges, and finally perfuse the injured DRG neuron with different potassium channel blockers in order to identify the underlying dynamic rules of variations in the rhythmic patterns of neuronal discharges.

归纳和分析神经元放电的节律形式，应用不同K~+通道阻断剂灌流损伤DRG，观察神经元放电节律变化的动力学规律。

There are 11 gene bindings disappear in the normal group, but appear in the model group, and then disappear in the treat group, that indicates the 11 gene bindings are correlated with the epilepsy and Caohuozhimutang. After searching in the Gene Bank, 7 bindings in the 11 gene bindings are homogenic with the 8q31 ribosomal protein gene, 15p12 paraneoplastic neuronal antigen gene, 4q22 diacylglycerol kinase iota gene, xq37 FMR2 protein and 11p11 roudabout homolog 1, and 4 bindings of which are novel gene.

经NCBI美国国家基因库检索，这11条基因中的7条已知基因分别与位于鼠染色体8q31位置的核糖体蛋白、15p12位置的周围肿瘤神经元的抗原(paraneoplastic neuronal antigen)、4p22位置的甘油二酯酶、xq37位置的FMR2蛋白（FMR2 protein）的基因以及以及位于果蝇染色体11p11位置的交叉同族体（roundabout homolog 1）有极高的同源性；有4条基因片段同源性较低，为功能未知的新基因，已经在GeneBank进行了注册，注册号分别CK325391、CK325392、CK325393、CK325394。

At histopathologic analysis, neuronal tumors are usually classified as pure neuronal cell tumors (gangliocytoma, Lhermitte-Duclos disease , central neurocytoma) and mixed neuronal-glial tumors (ganglioglioma, desmoplastic infantile ganglioglioma, dysembryoplastic neuroepithelial tumor, ganglioneuroma).

根据组织病理学的分析，神经元肿瘤通常被分为：单纯的神经元细胞肿瘤（神经节细胞瘤，Lhermitte-Duclos 病〔发育不良性小脑神经节细胞〕瘤），中枢神经细胞瘤）和混合性的神经元-胶质肿瘤（神经节神经胶质瘤，成结缔组织性婴儿节细胞胶质瘤，胚胎发育不良性神经上皮瘤，神经节瘤）。

In response to OVA stimulation, the amount of c-Fos and glial fibrillary acidic protein increased, while that of neuronal nitric oxide synthase decreased in the nucleus tractus solitarius.

结果，在卵白蛋白刺激下，c-Fos的量上升，glial fibrillary acidic protein也上升，但是neuronal nitric oxide synthase在孤立径核却是下降的。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。