查询词典 nephrotoxic

Also, at this stage nephrotoxic myoglobin released from the disrupted muscle cells floods the circulation, creating the possibility of acute renal failure.

同时，对肾脏有害的肌红蛋白也从损坏的肌细胞中进入循环，可导致急性肾衰竭。

Our study demonstrates that Nrf2-deficiency enhances susceptibility to both ischemic and nephrotoxic acute kidney injury, and identifies this transcription factor as a potential therapeutic target in these injuries.

我们的研究表明， Nrf2与缺陷增强敏感性和对缺血性急性肾损伤肾，并确定这一转录因子作为一个潜在的治疗靶点在这些injuries。

rrALR can promote the regeneration of tubular cells in nephrotoxic ARF rats and ameliorate renal dysfunction.

rrALR对急性损伤的肾小管上皮细胞具有减轻病变和促进再生修复的作用，可明显改善ARF大鼠的肾功能。

AIM: To observe the changes in infiltrating macrophagesand extracellular matrix in the kidney in the progressive course of nephrotoxic nephritis.

目的：观察肾毒血清肾炎发病过程中肾组织巨噬细胞浸润与细胞外基质含量的动态变化。

Based upon the synthetic procedure, we can rationally modify the molecular structure of CsO to screen out the more active and less nephrotoxic peptidomimetics.

在 CsO 的化学合成的基础上，我们可以进一步通过结构活性关系研究来筛选出活性更高、毒性更小的多肽类似物。

Within each drug class, preference may be given to agents less likely to be influenced by renal clearance, which are minimally nephrotoxic, or for which appropriate methods of prevention for renal toxicity exist.

目前提倡的是尽可能使用对肾清除率影响较小的药物，从而产生较小的肾毒性，或通过适当的方法预防肾毒性的发生。同时在使用已知肾毒性的多种药物应该尽量避免或减量。

METHODS: NTN model was established with rabbit-anti-rat nephrotoxic serum.

用兔抗鼠肾毒血清复制NTN模型。

The fate of the remainder was unknown when the Committee on Blood and Blood Derivatives began to investigate dextran, but it was thought that the larger molecules were probably deposited in the reticuloendothelial system and that they might be nephrotoxic or hepatotoxic.

当血液和血液衍生物委员会开始调查葡聚糖时，残余部分的命运还不为人所知。人们认为，较大的分子很可能存放在网状内皮系统，可能是肾中毒的或肝毒素性的。

BACKGROUND: Increased inorganic fluoride levels after methoxyfluraneexposure in the 1970s and prolonged intraoperative sevofluraneuse have been suggested to be potentially nephrotoxic.

背景：上世纪70年代使用的甲氧氟烷能导致机体无机氟化物水平的增加和术中长时间使用七氟醚被认为具有潜在的肾毒性。

Data for 4,228 cases and 84,540 controls matched on age and follow-up time were analyzed by using conditional logistic regression, adjusted for sex, age, health status, health care utilization measures, exposure to contrast agents, and nephrotoxic medications.

对于所有的服用NSAIDs者而言，在30天之内开始治疗，其发生急性肾衰竭的危险性最高（调整率比=2.05，95%置信区间：1.61，2.60）。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。