查询词典 naphthoquinone

The cytotoxicity of these compounds were valuated by MTT and SRB methods using three cancer cell lines: HL-60, A-549, P-388. Cyclo-shikonin, and cyclo-alkannin have high cytotoxicity against HL-60.The chiral center of side chain has no effect on their activity. 2- 1-(Acetyloxy-4-methyl-3-pentenyl -5, 8-dihydroxy-1, 4-naphthoquinone (105) has strong inhibition effect on P-388 cells. 2- 1-(isooctyloxy-4-methyl-3-pentenyl -5, 8-dihydroxy-1, 4-naphthoquinone (108) and 2- 1-(2-furoyloxy-4-methyl-3-pentenyl -5, 8-dihydroxy-1, 4-naphthoquinone (112) have high inhibition on A-549.Shikonin (1), alkannin (2), and their derivatives have the structural features of a planar chromophores and short side chain. We examined the ability to inhibit the telomerase.

抗肿瘤活性初步筛选测试采用小鼠白血病P-388肿瘤细胞和人肺癌A-549肿瘤细胞进行，结果表明侧链羟基的手性对抗肿瘤活性无明显影响；有数个化合物具有很好的体外抑制活性，特别是化合物2-（1-异辛酰氧基-4-甲基-3-戊烯基）-5，8-二羟基-1，4-萘醌（108）和2-[1-（2-呋喃甲酰氧基）-4-甲基-3-戊烯基]-5，8-二羟基-1，4-萘醌（112）体外显示对人肺癌A-549肿瘤细胞有强效；2-（1-乙酰氧基-4-甲基-3-戊烯基）-5，8-二羟基-1，4-萘醌（105）对小鼠白血病P-388肿瘤细胞有强效；环紫草素和环异紫草素对人白血病HL-60细胞有强烈抑制作用。

The inactivation of chironomid larvae in water supply systems was experimented with environment degradable vitamin K3,its main component 2-methyl-1,4-naphthoquinone,and their congener menadione triamintriazine bisulphite.

采用易被环境分解的维生素K3、其基本成分β-甲基萘醌和同系物三氨基三嗪甲萘醌亚硫酸盐，对在给水系统中出现的4龄摇蚊幼虫进行了杀生实验。

A novel and simple spectrophotometric method for determination of hydroquinone with 1,2-naphthoquinone-4-sulfonate reagent was developed.

建立了用1，2-萘醌－4-磺酸钠分光光度法测定对苯二酚的新方法。

Terahertz time-domain spectroscopy has been used to measure the spectral properties of polycrystalline 1,2-naphthoquinone, 1,2- naphthoquinone-4-sulfonic acid sodium salt , Menadione, Plumbagin, Juglone at room temperature.

用太赫兹时域光谱技术研究了室温条件下的萘醌及其衍生物1，2-萘醌、1，2-萘醌-4-磺酸钠、甲萘醌、白花丹素、胡桃醌的光谱特征，得到了各自的吸收谱和折射率。

In the traditional process,β-methylnaphthalene is oxidized with solution of chromic acid to give β-methylnaphthoquinone. However, a great deal of waste water with chromium will be produced in the process, which is very serious to environment. At the same time, the raw material consumption is great, which lead to the high production cost. Furthermore, by-product 6-methyl-1, 4-naphthoquinone will be produced, which is difficult to be separated completely and be utilized solely.

传统的生产工艺是用铬化物氧化β-甲基萘制备β-甲基萘醌，此工艺在生产过程中会产生大量的含铬废水，处理繁杂困难，对环境污染十分严重，并且原料消耗大，成本高，反应过程中的副产物6-甲基-1，4-萘醌未能加以彻底分离和利用。

Rate constants of carbon dioxide radical anion〓 reacting with 5,5dimethyl-1-pyrroline-N-oxide、1-naphthoquinone and N,N,N,N-tetramethyl 1,4 -phenylene diamine were determined by detecting the changes of radical concentrations with time, and they were 5.5×10〓mol〓Ls〓、4.5×10〓mol〓Ls〓 and 6.7×10〓nol〓Ls〓 respectively.

测定了在含〓的CdS胶体体系中〓与5，5-二甲基-1-吡咯氮氧化物、1-萘醌和N，N，N，N-四甲基对苯二胺正离子自由基反应的速率常数，它们分别为5.5×10〓mol〓Ls〓、4.5×l0〓mol〓Ls〓和6.7×10〓mol〓Ls〓。

It's has been reported that lactoquinomycin and frenolicin B, analogues of kalamycin, can inhibit AKT for the pyran naphthoquinone skeleton they have. We found that although kalamycin has pyran naphthoquinone skeleton, but did not suppress AKT and its downstream signal system, then we make a sytematic analysis on the in vitro anti-tumor effect and mechanism of kalamycin.

有报道其类似物lactoquinomycin和frenolicin B是肿瘤靶点AKT抑制剂，并由此推断吡喃萘醌骨架在AKT抑制过程中发挥主要作用，我们发现虽然卡拉霉素含有吡喃萘醌骨架，但是并不抑制AKT及其下游信号系统；继而对卡拉霉素的体外抗肿瘤作用及其机理进行了系统的分析。

First, 5-nitro-1 and 4-naphthoquinone are prepared through nitration and oxidization of naphthalene, and then through reduction of nitro into amide, diazotisation of the amide and hydro-lytic action of diazo salt, the juglone is made.

萘经过硝化、氧化生成5-硝基-1，4萘醌，然后硝基还原成氨基、氨基重氮化、重氮盐再水解，最终用新方法制得胡桃醌。

The type and position of substituents affected OWF〓 greatly for naphthoquinone and anthraquinone derivatives.

4取代基类型和取代基位置对OWF〓有较大的影响，如萘醌类发色母体、蒽醌类发色母体等。

Reactions of 2-methyl-1,4 naphthoquinone with human telomeric DNA and telomerase RNA ESR spin elimination has been used with 4-oxo-TEMPO as spin trap. The reactivities of 3VK3* with telomeric DNA, template of telomerase RNA and its L6-P6 region have been confirmed respectively. The results show that the reactivity of 3VK3* with polynucleotides is directly proportional to their G amount, and the one for reaction of 3VK3* with telomeric DNA is the highest in polynucleotides. 2. Reactions of 2-methyl-1,4 naphthoquinone with nucleosides, nucleotides ESR spin elimination has been used with 4-oxo-TEMPO as spin trap.

2-甲基-1，4萘醌与端粒DNA及端粒酶RNA亚基光敏反应性的研究应用ESR自旋消减法，对2-甲基-1，4萘醌(VK3)与端粒DNA重复序列、端粒酶RNA亚基模版序列、端粒酶RNA亚基L6-P6发夹区关键序列的光敏反应性进行了研究，结果表明，在一定波长照射下，明显诱导VK3与上述寡聚核苷酸反应，其反应性大小与核酸中鸟嘌呤含量正相关，其中端粒DNA序列反应性最强。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。