查询词典 myogenesis

The interaction between Mdfic and Rhox5 protein implied that they may form into complex for transcriptional control and then regulate the determination and differentiation during myogenesis.

Rhox5与Mdfic间的相互作用暗示了两者可能组成转录调控复合体在肌细胞发生和分化中发挥重要作用。

Myostatin is a negative regulator of myogenesis, which inhibits myogenic cell differentiation by down-regulating MyoD expression, but the specific mechanisim is not yet completely clear.

Myostatin基因，是肌肉生长的负调控因子，通过下调MyoD的表达抑制骨骼肌细胞的分化，但具体机制目前尚未完全清楚。

Our results suggest that several signaling pathways are involved in regulating Tbx6 expression, and pave the route to reveal the molecular mechanism of how myogenesis is initiated.

Xnot对Tbx6早期起始以及晚期维持表达都没有影响，提示其它基因参与限制Tbx6的空间特异性表达。我们的结果揭示了可能参与调控Tbx6表达的上游基因，为进一步揭示肌肉发生起始的机制提供了研究基础。

To understand whether myf5 plays other roles than myogenesis during embryogenesis.

另ㄧ方面，抑制myf5的转译，亦会导致原肠化异常、体轴与头部畸形(Chen and Tsai 2002)。

To generate recombinant adenovirus expression vector of human Sema4C gene and observe its expression in mouse myoblasts cell line C2C12 for ensuring easy access to investigate the role of Sema4C gene during myogenesis.

利用Ad5腺病毒载体系统构建人Sema4C基因重组腺病毒表达载体并在成肌细胞系C2C12中表达，并初步探讨Sema4C基因在成肌发育过程中的可能作用。

C2C12 cells were induced to differentiation into muscle cells in vitro and the myogenesis model was detected by inverted microscope, RT-PCR, western-blot, cell immunofluorescence histochemistry, flow cytometry and confirmed to be successful. On the foundation of differentiation model, miR-206 was detected by northern hybridization and the result showed that the expression level increasing gradually during muscle differentiation with a character of phase specificity.

利用C2C12细胞在体外成功诱导其向成肌细胞分化，通过形态学观察，RT-PCR、western-blot、细胞免疫荧光组织化学及流式细胞仪等方法进行检测，证实我们所建立的细胞分化模型是成功的，并观察到随着诱导时间的延长，miR-206在成肌分化过程中表达量逐渐增高的，表达改变具有阶段特异性。

They are determination factors in skeletal muscle myogenesis. They consist of MyoD, myf5, myogenin and MRF4. They play an important role in embryonic muscle development. They can activate the expression of muscle specific gene. They express in a temporal and spatial pattern in muscle development.

成肌调节因子是一组转录因子，它们是胚胎时期骨骼肌发生的决定因子，该家族主要有4个成员：MyoD、Myf5、Myogenin和MRF4，它们在胚胎时期肌肉发生中起着重要的调控作用，能激活肌肉特异性基因的表达。

Extracellular calcium is required for normal progression through the initial recognition-alignment phase of myogenesis. A net calcium influx into fusion-competent myoblasts is a requisite step in membrane fusion.

细胞与细胞之间识别和并列的初期阶段，胞外钙离子的内流是正常肌细胞生成过程所必不可少的，钙离子进入具有融合潜能的成肌细胞内，从而使细胞膜发生融合。

The forced expression of myogenin could induce NIH3T3 fibroblast to differentiate into myogenesis, it was identified as a pair of bands on SDS-PAGE. The phosphorylated form implies a significant structural change in the myogenin protein, which is expected to affect its function at post-translational level.

强制性表达外源性生肌素可启动NIH3T3成纤维细胞分化，进入成肌过程。pCD1-myog转染后的蛋白印迹带型迁移率发生改变，说明磷酸化导致生肌素蛋白结构的明显变化，并可能在翻译后水平影响其功能。

To study the role of FoxO1 on myoblast proliferation and differentiation and the transformation of muscle fiber type in porcine,here we use yorkshire as experimental materials and detect the expression of genes related myogenesis and muscle fiber type in pporcine myoblast that was knockout or activated FoxO1,adopting the technology of RNAi,real time-PCR and Western blotting et al..

为探讨FoxO1对猪成肌细胞增殖分化及肌纤维类型转化的作用及机理，本试验以大白猪为研究材料，利用RNAi、real-time PCR、免疫细胞化学和Western blotting等技术，通过在原代培养的猪成肌细胞中敲除和激活内源活性FoxO1，检测肌肉形成与肌纤维类型相关基因的表达。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。