查询词典 myelin

The authors stress that they cannot prove whether antibodies against MOG and MBP have demyelinating capacity or whether they represent an epiphenomenon of myelin destruction.

作者强调，他们不能证明抗MOG和抗MBP抗体是否具有使髓鞘脱失的能力，或它们是否表示髓鞘受到破坏的现象，作者表示，抗MOG和抗MBP抗体的分析对于临床上出现分离症状的患者而言，是迅速、低廉，和精确的早期临床预测法，可以预测多重硬化症的发展，而这项研究结果对于咨询和推测发生第一次髓鞘脱失之患者是否患有多重硬化症，是相当重要的。

Neural cell adhesion molecule L1, discovered in the 80s, is one of the matters that can promote nerve regeneration. It can mediate the interaction of cell-to-cell and cell-to-matrix, take great efforts on neurite outgrowth and fasciculation, migration of neural cells, formation of the myelin, structure of neural trace, transmembrane signal transduction, inhibiting apoptosis of neural cells, even on immune system and formation of the tumor. Li is discovered on the mouse's Cerebellar membrane primarily. Thereafter, it also is found in post- mitotic neurons, pre- and non-myelinating Schwann cells and so on.

神经细胞粘附分子L1（L1）是80年代发现的具有促进神经再生作用的物质，它能介导神经细胞与神经细胞之间的粘附，在神经轴突的生长、聚集，神经细胞的转移，纤维髓鞘的形成，神经通路的构建及信号的转导，抑制神经细胞的凋亡甚至在免疫系统、肿瘤的发生等方面均具有非常重要的作用。L1最初是从小鼠的小脑膜中发现，后来发现在有丝分裂后的神经元，髓鞘形成前及非形成髓鞘的雪旺细胞等组织中同样存在。

The notable proliferation was not observed by eyes in the local of injection. The infiltration of inflammation cells and mild proliferation of fibrocyte around dura mater was observed by HE stained in 4 and 8 weeks after injection. Infiltration and exudation of inflammation cells was observed by HE stained in epidural nerve root. Compared with group A, no changes of group B, C and D were observed under specific stained. Proliferation of type Ⅱ collagen fibers around dura mater was seen under immunohistochemical stained in 4 and 8 weeks after injection. There is no significant demyelination changes under LFB stained. The thickness and shape of the myelin sheath in epidural nerve root was not regular under transmission electronic microscopy in 4 and 8 weeks after injection. Fibroblast was also seen there. In nerve endometrium, macrophage could be seen under TEM, myelinated nerve fiber changed significantly, but nonmyelinated nerve fiber changed mildly. When 8 weeks, the changes of group D is smaller than the group B and C.

给药局部肉眼观察未见明显的纤维组织增生；HE染色可见B、C、D三组给药后四周及八周时硬膜内外均有炎细胞浸润，纤维细胞轻度增生，硬膜外神经根内有炎细胞浸润及炎性渗出；特殊染色B、C、D三组同A组相比未见有脊髓及神经根的改变；免疫组化染色，给药后四周及八周时，硬膜内外均有Ⅱ型胶原纤维增生；固兰染色B、C、D三组未见有明显脱髓鞘改变，与A组相比无明显异常改变；电镜观察B、C、D三组在给药后的四周及八周时，表现为硬膜外神经根内髓鞘厚薄不一，形状不规则，可见成纤维细胞，神经内膜中可见有巨噬细胞；粗大的有髓神经纤维变化明显，无髓神经纤维受累较轻；八周时电镜下D组改变较B、C两组为轻。

Results In both groups after injury, several changes on oculomotor nerve occurred including number reduction of neurons, dispersion in distribution, disappearance of sub-nuclear structure, structure destruction of fibers and myelin sheath, neurite gemmation, and specificity decrease in fibers distribution, while all these changes in section-suture group were more obvious.

结果 不同损伤均可导致神经元的数量减少，分布散乱，亚核分布结构改变，神经纤维和髓鞘的结构破坏，轴突芽生及再生纤维分布的特异性降低，而且上述改变在神经切断组更加明显。

Glia cells that produce the myelin sheath around axons in the central nervous system.

少数突神经胶细胞：在中枢神经系统的轴细胞周遭的髓鞘著产生的胶细胞。

Objective: To assess the significance of axonal growth inhibitor oligodendrocyte-myelin glycoprotein in acute spinal cord injury.

目的：探讨轴突生长抑制因子OMgP在急性脊髓损伤中的意义。

Results Compared with the control group,anxious rats demonstrated an incompact and vacuolar myelin sheath.

结果与生理盐水组比较，焦虑模型组大鼠杏仁核组织髓鞘出现肿胀变性、板层结构松解、脱髓鞘。

Membrane alterations (membrane vacuoles, invagination into adjacent organelles, and myelin figure-like changes) occur in a subpopulation of mitochondria in sepsis, but other hepatocyte organelles showed no consistent ultrastructural injury.

败血症中膜的改变（膜泡，向邻近的细胞内陷和髓磷脂形态样的变化）发生在线粒体的亚群，但是其他肝细胞器官未见一致的超微结构损伤。

Results: The main ultrastructural changes after Cd treatment included swelling or vacuolation of mitochondria, increase of myelin figures in GCT cells, and swelling of mitochondria in the endothelial cells of peritubular capillaries. The changes above were most prominent at 7~15d, and swelling of the cytoplasm and slight karyolysis were also found. The morphology of GCT cells didn't recovery to normal yet after 30d.

结果：镉注射后24h，GCT细胞内出现不同程度的线粒体肿胀和空泡化，胞质和线粒体内可见髓样结构，GCT周围毛细血管内皮细胞线粒体肿胀。7~15天后上述改变明显加重，部分GCT细胞见胞质广泛肿胀和轻度核溶解，30天后细胞形态仍未恢复正常。

Brain biopsy revealed severe damage to the myelin sheath. Question is,why?

脑活检显示有严重的髓鞘损伤问题是为什么会这样？

For a big chunk of credit-card losses; the number of filings (and thus charge-off rates) would be rising again, whether

年美国个人破产法的一个改动使得破产登记急速下降，而后引起了信用卡大规模的亏损。

Eph. 4:23 And that you be renewed in the spirit of your mind

弗四23 而在你们心思的灵里得以更新