查询词典 mutations

The frequency of three mitochondriai point mutations,1555A→G,3243A→G,7445A→G,was examined using restriction fragment length polymorphism annlysis in 262 Chinese patients with NSHL,con- sisting of 168 sporadic cases,69 sib pairs,and 25 families with affected subjects in more than one generation.

方法收集非综合征型神经性耳聋病例262例，其中散发病例168例，69例同代有耳聋患者，25例不止1代有耳聋患者，采用限制性片段长度多态性分析线粒体基因中的下列3个点突变：1555A→G，3243A→G，7445A→G。

Testing of relatives at risk: In the newborn sibs of a proband , it is appropriate to either assay ADA catalytic activity or perform molecular genetic testing (if the family-specific disease-causing mutations are known), so that morbidity and mortality can be reduced by early diagnosis and treatment.

对高危亲属的检测：对先证者的新生同胞兄妹，检测ADA催化活性或进行分子遗传学检测（如果已知家族特异性致病突变）都是合适的，这样早期诊断和治疗便能降低发病率和病死率。

Scientists at Oregon university argue in Nature magazine that their research with roundworms – which can self-fertilise or reproduce sexually – shows selfing populations are more susceptible to harmful genetic mutations and slow to adapt to swiftly changing environmental conditions.

俄勒冈大学的科学家在《自然》杂志上撰文称，在对既可以自体受精、也能够有性繁殖的蛔虫进行研究后发现，自体受精的后代更容易受到有害基因突变的影响，对迅速变化的环境条件的适应速度也比较慢。

In conclusion, the mutations of rpoB gene in this research are consistent to the other research repots from internal and external coutry.

与DNA测序结果比较，168株中有164株被判定为耐药株，4株判定为敏感株；132株测序未发现突变的菌株中129株被判定为敏感株，3株被判定为耐药株。

This result was also confirmed by neomycin gene-containing replicons with same mutations.

这一结果在新霉素包含子转染中也得到了证实。

Luciferase activities were measured 72 hr post-transfection. All three mutants showed higher luciferase activity than that of the wild type, and the V85I mutant showed the highest activity. This result was also confirmed by neomycin gene-containing replicons with same mutations.

荧光素酶活性在转染后72小时检测。3种突变子均显示荧光素酶活性高于野生型，V85I突变子显示最高的活性。

In the study, to investigate the effects of mutations in dengue virus C gene and its encoded protein on viral replication, a series of dengue virus replicon mutants were constructed and their replication efficiencies were compared.

在登革病毒中，尚无C蛋白参与调节病毒复制的报道，而在C基因中是否存在其它影响病毒复制的RNA结构元件的问题也没有明确的答案。

The main purpose of this experiment was to design a device, the device plate for the experiment to target in a different effort, the achievement of plate-shaped Cup mutations, testing effort and deformation of the relationship.

本文的主要目的是设计一种实验装置，该装置以板材为实验对象，可在不同作用力下，实现板材的杯突变形，测试作用力与变形量的关系。

Finally, all mutations of FV gene in probands and their family numbers were confirmed by .restriction enzyme analysis.

从两位患者的家系的初步调查结果分析，也表明符合常染色体隐性遗传规律。

Clinical evaluations demonstrated familial apical HCM in 4 probands, and in 3 probands disease-causing mutations were identified.

临床评价显示4个患者为家族性心尖肥厚型心肌病，并在3个患者验明致病基因突变。

But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊！不用提了。提到肉，真是糟透了。