查询词典 mutations

The frequency of three mitochondriai point mutations,1555A→G,3243A→G,7445A→G,was examined using restriction fragment length polymorphism annlysis in 262 Chinese patients with NSHL,con- sisting of 168 sporadic cases,69 sib pairs,and 25 families with affected subjects in more than one generation.

方法收集非综合征型神经性耳聋病例262例，其中散发病例168例，69例同代有耳聋患者，25例不止1代有耳聋患者，采用限制性片段长度多态性分析线粒体基因中的下列3个点突变：1555A→G，3243A→G，7445A→G。

Testing of relatives at risk: In the newborn sibs of a proband , it is appropriate to either assay ADA catalytic activity or perform molecular genetic testing (if the family-specific disease-causing mutations are known), so that morbidity and mortality can be reduced by early diagnosis and treatment.

对高危亲属的检测：对先证者的新生同胞兄妹，检测ADA催化活性或进行分子遗传学检测（如果已知家族特异性致病突变）都是合适的，这样早期诊断和治疗便能降低发病率和病死率。

Scientists at Oregon university argue in Nature magazine that their research with roundworms – which can self-fertilise or reproduce sexually – shows selfing populations are more susceptible to harmful genetic mutations and slow to adapt to swiftly changing environmental conditions.

俄勒冈大学的科学家在《自然》杂志上撰文称，在对既可以自体受精、也能够有性繁殖的蛔虫进行研究后发现，自体受精的后代更容易受到有害基因突变的影响，对迅速变化的环境条件的适应速度也比较慢。

In conclusion, the mutations of rpoB gene in this research are consistent to the other research repots from internal and external coutry.

与DNA测序结果比较，168株中有164株被判定为耐药株，4株判定为敏感株；132株测序未发现突变的菌株中129株被判定为敏感株，3株被判定为耐药株。

This result was also confirmed by neomycin gene-containing replicons with same mutations.

这一结果在新霉素包含子转染中也得到了证实。

Luciferase activities were measured 72 hr post-transfection. All three mutants showed higher luciferase activity than that of the wild type, and the V85I mutant showed the highest activity. This result was also confirmed by neomycin gene-containing replicons with same mutations.

荧光素酶活性在转染后72小时检测。3种突变子均显示荧光素酶活性高于野生型，V85I突变子显示最高的活性。

In the study, to investigate the effects of mutations in dengue virus C gene and its encoded protein on viral replication, a series of dengue virus replicon mutants were constructed and their replication efficiencies were compared.

在登革病毒中，尚无C蛋白参与调节病毒复制的报道，而在C基因中是否存在其它影响病毒复制的RNA结构元件的问题也没有明确的答案。

The main purpose of this experiment was to design a device, the device plate for the experiment to target in a different effort, the achievement of plate-shaped Cup mutations, testing effort and deformation of the relationship.

本文的主要目的是设计一种实验装置，该装置以板材为实验对象，可在不同作用力下，实现板材的杯突变形，测试作用力与变形量的关系。

Finally, all mutations of FV gene in probands and their family numbers were confirmed by .restriction enzyme analysis.

从两位患者的家系的初步调查结果分析，也表明符合常染色体隐性遗传规律。

Clinical evaluations demonstrated familial apical HCM in 4 probands, and in 3 probands disease-causing mutations were identified.

临床评价显示4个患者为家族性心尖肥厚型心肌病，并在3个患者验明致病基因突变。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。