查询词典 mutations

His concept is that you use the dugs which may induce mutation as early as several months or sometimes several weeks, that's why he has to check the DNA mutations, but there are now some drugs available who are OK for 5 years. If so, why you have to worry about mutation by performing expensive DNA frequency.

Keeffe教授的概念是指如果你所使用的药物是在用药几周或者几个月后就会引起突变的话，在这种情况下就需要检测HBV DNA，而对于5年耐药率都很低的药物来说，就没有必要如此频繁地进行昂贵的检测了。

It is important to note, however, that different mutations in the dystrophin gene could require different oligonucleotide drugs.

重要的是要注意，不过，在不同的肌营养不良基因突变可能需要不同的寡核苷酸药物。

About 10 to 15 percent of all DBMD cases are caused by nonsense mutations in the dystrophin gene.

大约10到15的所有DBMD案件中有百分之是由于在肌营养不良基因无义突变。

Searching for the 1 in 2 400 000: a review of dystrophin gene point mutations.

用18对引物进行假性肥大型肌营养不良症的基因诊断。

Based on brief introduction of nutritional components,development,and genetic control of endosperm,it is reviewed on a serial of novel mutations,such as the waxy,dull,misty,sugary,shrunk,floury,low amylose,high amylose, low paste viscosity,high resistant starch,low glutelin content,protein body absent,high iron,low phytic acid endosperms and gene locations of the related mutated characters.

本文在简要介绍胚乳的发育、组成及品质性状遗传的基础上，综述了与淀粉、蛋白质和微营养相关的系列胚乳突变及相关性状的基因定位。胚乳突变主要包括糯性、暗色、云雾状、糖质、皱缩、粉质米、低直链淀粉、高直链淀粉、低粘滞性、高抗性淀粉、低水溶性蛋白、蛋白体缺失、高赖氨酸、高铁、低植酸等方面。

1764 Nucleotide mutations of HBV was identified by cccDNA sequence analysis when detectable, or by PCR of HBV X gene segment spanning the mutation region. Sequence homology analysis was accomplished by using Entrez software.

其中，72例为肝细胞癌，18例为终末期肝硬化，对外科切除和穿刺标本的病理学分析表明这些人群普遍存在慢性活动性肝炎的病理背景。

We evaluated HSF efficiency using a set of 83 intronic and 35 exonic mutations known to result in splicing defects.

我们使用一个已知导致剪切缺陷的83个内含子和35个外显子的突变来评估HSF的效率。

PCR-SSCP method was used to detect mutations in exons 2,3,4 of runx3 gene in the gastric carcinoma.

结果：2例胃癌标本在runx3的第3外显子发现突变，第2、4外显子未发现突变改变。

Results:p53 gene mutations in exons 7 and 8 were found in 37 thyroid carcinoma patients (29.7%).

有关 p53基因在甲状腺癌中的研究，国内少有报道。

In order to study the effects of 3 protein-4.2 point mutations associated with HS, we have cloned four recombinant fusion proteins: GST-P4.2 (31-200) D175Y, GST-P4.2 (31-200) D175Y, GST-P4.2 (100-260) D175Y, GST-P4.2 (31-200) A142T with pointmutation, to do prokaryotic expression, and tested their interactions with ankyrin by Far-Western blot and Pull-down assay, but there were no evidences to show these mutated proteins can bind to ankyrin except GST-P4.2 (31-200) A142T.

于是我们采用了点突变的方法，克隆表达了4种重组的突变蛋白GST-P4.2(31-200)D175Y、GST-P4.2(31-200)D175Y、GST-P4.2(100-260)D175Y，GST-P4.2(31-200)A142T，发现第175位氨基酸残基的突变使得相应的重组蛋白均不能与ankyrin直接相互作用，而第142位氨基酸残基的突变对P4.2与ankyrin之间的相互作用没有影响，这说明第175位氨基酸对于P4.2与ankyrin的结合是非常重要的，很可能是一个关键位点。

But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊！不用提了。提到肉，真是糟透了。