查询词典 mutations

Results Only unstable random mutations happened in 29 sites with nonsynonymous vs synonymous mutation ratio of 1.42 during 50 passages in 2 serials without maternal antibodies.

LG1株H9N2在没有抗体的鸡胚的传代过程中，仅发生少数碱基的不稳定随机变异，且多为无义突变。

However, multiple stable nonsynonymous mutations were detected gradually during 50 passages of 4 serials in embryos with maternal antibody to LG1 strain, and the NS/S ratio was as high as 3.46 among 45 mutated sites.

在2 个传代系列的10 个代次病毒，共出现了29 个位点变异，有义突变与无义突变比值NS/S为1.42 。但在有抗体的鸡胚的传代过程中，发生了多个呈现稳定遗传的有义突变。

These results indicated that the genetic variation within exon 2 appeared to have largely arisen by gene recombination and balancing selection. Alignment of the deduced amino acid sequences of the β1 domain coded by exon 2 revealed 6 synonymous mutations and 27 nonsynonymous substitutions at the 33 disparate sites.

对B-LBⅡ等位基因第二外显子所编码的B-LBⅡ分子β1结构域氨基酸序列比对发现，31个B-LBⅡ新等位基因属于26个等位基因主型；在β1结构域氨基酸序列的33个变异位点上，存在6个同义替换和27个错义替换。

Compared with other HPV16 reference sequence, nucleotide sequencinganalysis of the HPV16 E6, E7 and L1 gene from Cervical Carcinoma Biopsis in Chengdu city and Chongqing of China consistently shows point mutations,including synonymous mutation and nonsynonymous mutation. This researchwill be helpful in preventing cervical cancer and designing vaccines which isspecific for the women in the two regions of China.

与标准序列比较，中国成渝地区HPV16亚型L1、E6和E7基因存在一定范围的变异，提示我们，在预防治疗成渝地区妇女宫颈癌病人以及研制开发针对成渝地区预防宫颈癌的HPV疫苗时，需要注意这些位点的变异，特别是一些引起氨基酸变异的位点。

In two patients, de novo mutations lead to an amino acid substitution.

结果表明，在两个患者的SRY基因中分别发现了新的核苷酸点突变，并都导致氨基酸替代。

In the second part of this study, skin and muscle fibroblasts were cultured from nine patients with chronic progressive external ophthalmoplegia syndrome for studying the relationship between mtDNA mutation and free radical scavenging enzymes. The skin and muscle fibroblasts from these CPEO patients carried different mtDNA mutations at different levels.

因此，我针对CPEO病人的皮肤和肌纤维母细胞的mtDNA突变和氧化性损伤进行分析，我以南方墨渍法分析皮肤和肌肉纤维母细胞的DNA，发现这9位病人所含的mtDNA突变差异性极大，有4，977 bp、 4，366 bp、 6，190 bp、约10 kb的大片段mtDNA断损突变和粒线体tRNALeu基因的A3243G点突变。

Yunnan province is the orchid resource gene bank in China even in the world with its abundant Orchidaceae resources including 135 genus, 764 species, 16 variations and other mutations types.

云南省具有十分丰富的野生兰花资源，共有兰科植物135属、764种及16个变种，并有众多的变异类型，是我国乃至世界的兰花资源宝库。

The homology ranged from 96% to 98%, and there were no frameshift mutations, which guaranteed the correct ORF.

这也进一步证实了本研究所筛选到的微生物的确是硝酸菌。

Background: Current literature suggests that up to 60% of papillary carcinomas have mutations in the BRAF gene.

背景：目前，文献报道有近60%的甲状腺乳头状癌发生了BRAF基因突变。

Objective To observe the histopathological features of piebaldism by confocal laser scanning microscopy in vivo and to investigate c-kit gene mutations in a family of piebaldism.

目的 报告一例斑驳病家系，运用共聚焦激光扫描显微镜对先证者进行实时在体组织学检查和诊断，并检测该家系患者c-kit基因突变位点。

But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊！不用提了。提到肉，真是糟透了。