查询词典 mutations

"Other chips have been developed to assess drug metabolism," said Jorge Bezerra, MD, a pediatric gastroenterologist at Cincinnati Children's and the study's lead investigator."This is the first chip in the world that has been customized to diagnose genetic mutations in patients with inherited types of liver diseases."

&其他芯片开发用于评价药物代谢，& Cincinnati儿童医院的儿童胃肠病学家、该研究的首席研究员，Jorge Bezerra博士说：&这是世界上第一种制定并用于诊断遗传型肝脏疾病患者遗传突变的芯片。&

Based on our initial results, the genotypic assay was then used to detect HIV-1 drug resistance mutations in 134 clinical samples from 92 HIV-1-infected individuals .

其次，我们对治疗前后的92例HIV-l感染者的134份临床标本进行了耐药性检测和进化树分析，并对HIV-1蛋白酶和逆转录酶基因的耐药性突变模式进行了研究。

GrroCHS8, a copy from Grevillea robusta, had many mutations at active sites, implying the new function may be developed in this copy.

在对碱基含量的分析中表明，只有来自雀舌黄杨的序列有一定的GC偏好，特别是第三位的GC含量达70%以上。

To study genetic mutations of methylenetetrahydrofolate reductase C677T and cystathioinine-β-synthase T833C related to homocysteine metabolism in patients with ischemic stroke, the MTHFR gene C677T gene mutation and the CBS T833C gene mutation were detected by PCR-RFLP or ARMS method in 74 patients with ischemic stroke and 83 normal people for control. Results showed that the frequencies of MTHFR genet homogenetic type(2.7%), heterogenetic type(51.4%) and T allele(28.4%) in ischemic group were higher than those in control group(1.2%, 39.8% and 21.1%, respectively).

为研究同型半胱氨酸代谢相关酶亚甲基四氢叶酸还原酶基因C677T和胱硫醚-β合成酶基因T833C位点碱基突变与缺血性脑卒中的关系，对74例缺血性脑卒中患者和83例健康对照者，采用聚合酶链反应-限制性片段长度多态性技术检测MTHFR基因C677T基因型，用扩增阻滞突变体系法检测CBS基因T833C突变。

Results In patients group,CBS genetic homozygous and heterozygous mutations were found in 9 cases and 28 cases respectively.

结果在脑梗死组有9例CBS基因纯合子突变，28例为杂合子突变；对照组3名为纯合子突变，5名为杂合子突变。

Approximately 1% of mutations occur de novo ; thus, 1% of probands have only one parent who is heterozygous.

约1%的突变是新生突变；因此，1%的先证者只有一个杂合子的父母。

It is partly because it is so easy to compare two sequence reactions and because it appears excellent in calling heterozygous mutations.

部分是它非常易于比较两个DNA序列，更主要是它在杂合子变异检测方面，表现非常出色。

Direct sequence analysis of exon 17 showed that homozygous and heterozygous nonsense mutations were silent polymorphism at position 1058.

结果 发现11例外显子17和1例外显子20的异常电泳条带，外显子17的突变经顺序分析，为CAC1058→CAT1058的杂合和纯合多态性突变。

Objective To study RB1 heterozygous mutations in patients with retinoblastoma.

目的 检测视网膜母细胞瘤病人体细胞中RB1基因突变，探讨RB1基因突变的分子生物学机制。

High copies and the homoplasmic mutation in tumor, mtDNA mutations may be attractive diagnostic markers for some cancers.

由于肿瘤中mtDNA的高拷贝、同质性突变等特点，有人提出mtDNA突变有希望成为肿瘤早期诊断的分子标记。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。