查询词典 mutations

CDH1 mutations in indiiduals from families with HDGC are associated with gastric cancer in a highly penetrant fashion.

患HDGC家族中的CDH1截断突变的个体以一种高侵袭方式与胃癌相关。

P. 01. Conclusion PTEN gene could inhibit microvessel production. So PETN mutations or deletions might play an important role in tumor progression and angiogenesis of bladder cancer.

PTEN基因突变或缺失所导致的表达障碍可能在膀胱癌的恶性进展、肿瘤浸润转移及血管生成过程中发挥重要的作用并与肿瘤的预后相关。

As noted on page 153, some case of this disease result from mutations in aquaporins, The water channels of the plasma membrane.

就像153页提到的，一些病例的致病原因是水通道的突变，即质膜上的水通道的改变。

More and more researchers were concerned with large transformations at the genome level, as opposed to point mutations at the sequence level.

相对于序列水平的点突变，越来越多的研究更加关注基因组水平的较大的变化。

In contrast to the homozygous mutated colonies seen with V617F-positive polycythemia vera, the colonies with this disorder featured heterozygous mutations.

V617F阳性的真性红细胞增多症的红细胞群落多为突变，与此对应的是：这类病症的红细胞群落以杂合变异为主要特征

He wanted to know if she had encountered, in all her case studies of interesting mutations, any references to a syndrome of human polyploidy.

在她所有的有趣畸变的个案研究中假如她遇到，他想要知道，关於人类的 polyploidy 的一种并发症状的任何参考。

Objective: To explore the characteristics of germline APC gene mutations in Chinese patients with familial adenomatous polyposis.

目的：探讨国人家族性腺瘤性息肉病患者APC基因胚系突变的特点。

Methods mEBP gene was predicatively analyzed by DNASIS software,and the mutations at sites 5 and 18 were induced by PCR site-directed mutagenesis.

方法以亲代EBP基因为基础，结合DNASIS软件理化性质分析确定突变碱基，应用PCR定点诱变技术进行第5、18位谷氨酰胺→赖氨酸的定点突变。

Methods mEBP gene was predicatively analyzed by DNASIS software, and the mutations at sites 5 and 18 were induced by PCR site-directed mutagenesis. The mEBP gene was cloned into prokaryotic vector pinpoint Xa-3 and transformed to E.

以亲代EBP基因为基础，结合DNASIS软件理化性质分析确定突变碱基，应用PCR定点诱变技术进行第5、18位谷氨酰胺→赖氨酸的定点突变。

Mutations in 26-amino acid downstream portion from the ISDR remained a prognosticator of SVR in the era of optimally tailored therapy.

故ISDR下游的26个胺基酸突变仍可作为当代合宜地个人化治疗时持续病毒反应的预测因子。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。