查询词典 mutations

The mutations in the quinolone resistance-determining regions of the gyrA and parC genes were analyzed by PCR and sequencing.

PCR扩增gyrA和parC基因的喹诺酮耐药决定区，扩增的片段长度分别为525bP和487bp， PCR产物直接测序。

The rapid evolution of a new species from a small population that is partially or totally isolated from the parent population; usually involves a few mutations that have a large impact on the organisms' observable physical traits.

这种方式通常在物种的物理性质上伴随着大规模变化。

Deletion mutations of parkin gene at exons 4,6,7 and 10 were not found in all of normal controls.

我国有关该基因的研究主要集中在早发性PD，而对家族性PD的研究较少。

The outcome of the operations is good effect on the PD patients with parkin gene deletion mutations.

尤其是有关Parkan基因外显子缺失的PD患者手术效果的报道，尚未见到。

Objective To explore parkin gene deletion mutations at exons 3 to 7 in Chinese familial patients with Parkinson's disease as well as the association with the clinical features.

目的 探讨中国家族性帕金森病患者parkin基因第 3～ 7外显子是否存在缺失突变，及其与该病临床特点的关系。

The pathogenicity of the mutations was confirmed by expression studies.

突变表达研究证实了这些突变的致病性。

In this report, several point mutations were introduced into this motif by PDR mediated site-directed mutagenesis.

在这一模体中引入点突变，ENII的增强子活性即显著下降，表明该模体对ENII的功能是重要的。

The contribution of these mutations to breast cancer risk within any specific population is a function of both their prevalence and their penetrance.

这些突变对不同特殊人群的乳腺癌风险的影响是它们患病率及外显率的作用。

HMLH3 missense mutations in family 7 and 8 may be pathogenic, but with reduced penetrance.

结论首次发现hMLH3基因C2825T和A2173C错义突变。hMLH3基因作为一新的风险基因，在家族性食管癌的发病中可能通过与其它基因互相叠加、共同起作用。

Except for genetic susceptibility due to mutations in highly penetrant genes e.g.

然而，治疗前乳癌增加的原因与世界其他有关。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。