查询词典 mutations

Incubation of these chips with the patient's DNA sample produce chemical signals that "glow" and allow for the detection of the normal gene sequence, or of mutations if they are present in the patient.

这些芯片和患者的DNA样本一起孵育，可发产生"发光"的化学信号，并检测出正常的基因序列或者突变的序列，如果在患者中存在的话。

The sequencing results were compared with the normal nucleotide sequence queried from the GeneBank database to discover the mutations.

测序结果与Gene Bank中该基因的正常序列对比找出突变，结合该家系成员临床表型证实突变。

Objective To analyze HBV drug-resistant mutations against nucleoside analogues at 12 reported sites in 340 patients with chronic hepatitis B.

目的 分析慢性乙型肝炎患者HBV逆转录酶基因与核苷类似物耐药相关的12个位点上的突变情况及其临床意义。

It is believed that the overwhelming majority of mutations have no significant effect on an organism's fitness.

人们认为绝大多数的突变对生物体的适合度没有显著的影响。

"We advocate prophylactic oophorectomy to reduce the risk of ovarian and breast cancer in women with BRCA1 and BRCA2 mutations," write Timothy R.

我们提倡对携带BRCA1 与BRCA2突变体的女性进行预防性卵巢切除术，以降低卵巢癌与乳腺癌的危险，」费城宾夕法尼亚大学的Timothy R。

To investigate the AR mutants function, the four mutations were constructed respectively into an expression vector containing the human AR cDNA using pALTER II mutagenesis system in vitro.

首先，我们应用pALTER体外致突变系统成功地对这些突变位点进行了人工致突变，构建了这些突变的表达载体，然后应用Western blot分析，对转染入无内源性AR表达的COS-7细胞中的表达载体的表达进行了分析，结果表明，表达载体能有效表达AR，其大小与野生型AR一致。

Gly, and the most common mutations in parC were Asp????

95→Gly。 parC基因最多见的突变是Asp？？？？

Mutations of gyrA and parC genes had contributed to the development of Fluoroquinolone resistance.

淋病奈瑟菌的耐药与gyrA和parC基因突变有关。

ObjectiveTo study the relationship between fluoroquinolone resistance in Neisseria gonorrhoeae and mutations in gyrA and/or parC genes.

目的研究淋病奈瑟球菌耐氟喹诺酮类药物与gyrA和parC基因突变的相关性。

Mutations in gyrA and parC genes are mainly responsible for the gonococcal resistance to ciprofloxacin.

延安地区淋球菌gyrA和parC基因突变是形成淋球菌耐环丙沙星的主要原因。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。