查询词典 mutation

This also loosens the constraints against failure, so the earlier the mutation is in development, the less likely it will be workable.

这样也放松了对抗发育失败所需的束缚，因此，发育过程中来得越早的突变，越不可能是有用的。

Of course , natural selection lops off the rough edges , but mutation is the spark plug - the creative source for engineering new species .

当然，自然选择 lops 小康粗糙的边缘，但突变是火花塞-创意的来源为工程新种。

The effect of a cI mutation is to prevent lysogeny, so that the plaques contain only lysed cells.

一种CI变异的效果是阻碍溶源性，于是空斑只含有裂解的细胞。

Those who know they carry the mutation sometimes choose preventive mastectomies

这类人群有时选择了预防性的乳腺切除术。

Those who know they carry the mutation sometimes choose preventive mastectomies.

那些得知自己携带BRCA1变异的妇女有时会选择预防的乳房切除术。

On the discussion about mechanism of mutation of methylating, we explored thermodynamics and dynamic properties on base pairs, investigating the proton transfer on base pairs.

从甲基化对嘌呤碱基电荷的影响，到甲基化引起碱基配对的改变造成碱基配对的诱变等都作了较为详细的探讨；在对甲基化诱变的探讨中，我们进行了热力学和动力学方面的研究，同时对碱基之间的质子迁移的难易程度也作了探讨；并在充分考虑水分子存在的情况下研究了甲基化对碱基之间的氢键作用和堆积作用的影响。

For example, by mutating a protein and analyzing the effect of this mutation in the cell, we can learn a lot about the normal function of the protein.

例如，通过使一种蛋白质发生突变并分析该突变在细胞中造成的影响，我们可以获得许多关于该蛋白正常功能的知识。

Dysregulation of the protein kinase A system, caused by mutation of the protein kinase A regulatory subunit gene PRKAR1A, causes the inherited tumor syndrome Carney complex, which includes cardiac myxomas as one of its cardinal features.

蛋白激酶A调节亚基因PRKAR1A的变化引起蛋白激酶A系统失调，导致了遗传性卡尼复合肿瘤综合症，其中包括了心脏粘液瘤作为它的一个主要特征。

BACKGROUND: Protein kinase A signaling has long been known to play an important role in cardiac function. Dysregulation of the protein kinase A system, caused by mutation of the protein kinase A regulatory subunit gene PRKAR1A, causes the inherited tumor syndrome Carney complex, which includes cardiac myxomas as one of its cardinal features.

背景：长期以来，蛋白激酶A信号途径被认为在心功能中起着重要作用，蛋白激酶A调节亚单位基因PRKAR1A的突变导致蛋白激酶A系统失调，引起遗传性肿瘤综合征－Carney合成，其中心脏粘液瘤作为其主要特征。

Background— Protein kinase A signaling has long been known to play an important role in cardiac function. Dysregulation of the protein kinase A system, caused by mutation of the protein kinase A regulatory subunit gene PRKAR1A, causes the inherited tumor syndrome Carney complex, which includes cardiac myxomas as one of its cardinal features. Mouse models of this genetic defect have been unsatisfactory because homozygote null animals die early in development and heterozygotes do not exhibit a cardiac phenotype.

背景——蛋白激酶A信号传导在心功能中发挥了重要作用早已为人们所知蛋白激酶A调节亚基因PRKAR1A的变化引起蛋白激酶A系统失调，导致了遗传性卡尼复合肿瘤综合症，其中包括的心脏粘液瘤作为它的一个主要特征此种遗传缺陷的小鼠模式仍然不能令人满意，因其纯合体空白动物在发展中早期死亡，而杂合体不能显示心脏表型

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。