查询词典 mutation

They showed that the mutation definitely reduces the number of malaria-causing Plasmodium vivax parasites, lessening the severity of the disease.

他们发现，这种变异致病基因显著减少了疟原虫感染病例的数量，并有效缓解了疟疾病患的病情。

The limit genetic mutation of Pvs48 reinforces that the vivax transmission-blocking vaccine base on Pvs48 would promise a good prospect for a wide range application in China.

有限的基因突变再次提示以Pvs48为基础构建的传播阻断疫苗在我国具有广泛应用的可行性。

One possibility is that it's just this particular combination of the eight parts that makes it spread among people, Webby said. But a more logical explanation is that a small mutation within the individual genetic segments changed things.

有一种可能性是这八个部分恰好组合成了能够在人群中迅速传播的性能，Webby说，但是，一个更合乎逻辑的解释是，基因片段中有一个微小的突变改变了病毒的传播特征。

Base mutation at sites 1 044 and 1 062 also led to produce a stop condon.

另外，在1044与1062的碱基突变也导致终止密码子的产生。

Methods Polymerase chain reaction was used to detect HPV 16 DNA and point mutation at condon 12 of Ha-ras oncogene.

应用多聚酶链反应技术扩增HPV16 DNA和Ha-ras癌基因相关片段，分别采用2％琼脂糖凝胶电泳和限制性片段长度多态性分析，检测口腔癌中的HPV16 DNA和Ha-ras癌基因第12位密码子的点突变。

Objective To investigate the mutation and expression of tumor suppression gene phosphatase and tensin homolog deleted on chromosome ten in patients with nasopharyngeal carcinoma.

目的 探讨抑癌基因PTEN在鼻咽癌细胞株及组织中的基因突变和蛋白表达缺失情况。

Our results suggest that coden 12 of the H-ras oncogene may be a specific target for the mutagenic activation by tobacco smoke, and smoking is an important factor in the induction of H-ras oncogene mutation.

提示H-ras基因可能是被烟草激活的一个特殊位点，吸烟是导致H-ras基因突变的重要因素。

Methods The samples were collected from 55 consecutive patients with tissue diagnosed lung cancers by fiberoptic bronchoscopic brushing. Mutation in coden 12 of H-ras oncogene was detected in the exfoliated cells using PCR-RFLP method (polymerase chain reaction-restriction fragment length polymorphisms).

对33例吸烟肺癌和22例不吸烟肺癌患者采用纤维支气管镜毛刷刷取支气管脱落细胞，应用PCR-RFLP方法进行H-ras基因突变检测。

EMB-resistance in 18 isolates was caused by the mutation at coden 306 in embB gene with positive rate of 62.1%. The PCR result was negative in 20 specimen from pulmonary diseases without active TB and 5 negative control strains of no MTB. The data in this study showed high specificity of 100%. Only one specimen in 7 specimen with negative result in acid-fast stain and cultivation was shown alteration in coden 306 in embB gene.

结果：130例活动性肺结核患者痰标本抗酸染色阳性38例，阳性率为29.2%(38/130)；罗氏培养阳性为79例，阳性率为60.8%(79/130)。79例培养阳性痰标本中耐乙胺丁醇29例，其中有18例在embB基因met306ATG突变，基因突变率为62.1%。20例非结核肺部疾病患者痰标本和5株非结核分枝杆菌菌株经套式PCR扩增全部为阴性，特异性为100%。7例涂阴培阴PCR扩增阳性的序列中有1例在embB基因306位密码了发生突变。

The mutation of Raf can be detected in many human cancers, so it was important target for therapeutic intervention.

Raf突变在多种恶性肿瘤中被探测到，因此是肿瘤介入治疗的重要靶点。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。