查询词典 mutation

Objective This study was to investigate the roles of TATA or G71R mutation of the undine 5'-diposphate-glucuronosyl transferase 1A1(UGT1A1) gene, A388G mutation of the organic anion transporter 2(OATP2), glucose-6-phosphate dehydrogenase(G-6-PD) deficiency to the development of neonatal hyperbiliidbinemia.

目的 探讨葡萄糖醛酸转移酶UGT1A1 TATA盒或G71R突变、有机阴离子转运因子2(OATP2)A388G突变、葡萄糖-6-磷酸脱氢酶(G-6-PD)缺乏对新生儿高胆红素血症发病的作用。

Anti-cancer and anti-mutation: Many researches prove that the acacatechin in the tea can restrain the cancer cell and the cell mutation.

抗癌及抗突变：许多研究证实茶叶中的儿茶素对癌细胞和细胞突变有抑制作用。

Results The mutation incidence of LKG was 22.96%, while the mean incidence of GPG was 7.59%(The incidences of C20-OH group, glucoside group and aglucon group were 5.32%, 6.25% and 11.00% respectively). When treated with DMBA for 4 to 8 weeks, the mutation incidence of LKG ranged from 11.10% to 40.00%, while GPG ranged from 0 to 10.70%.

结果 白斑癌变模型组突变率达22.96%，绞股蓝处理组平均为7.59%；绞股蓝各组抗突变率效佳依次为C20-OH组、总甙组、甙元组，其突变率分别为5.32%、6.25%、11.00%；DMBA诱导癌变4～8周时白斑模型组突变率为11.10%～40.00%，绞股蓝处理组为0～10.70%。

Alpha-1 antitrypsin is the most abundant circulating protease inhibitor in the body, Dr. Lomas said. Its most common deficiency mutation is the Z allele, where the amino acid lysine is exchanged for glutamic acid at position 342 in the polypeptide chain (Glu342Lys). About 1 in 1700 whites of northern European descent are homozygotes for this mutation and thus have plasma antitrypsin levels that are 10% to 15% below normal, he said.

Lomas博士表示，甲一型抗胰蛋白酵素是身体内最充分的循环蛋白酶抑制剂，最常见的缺损突变在Z对偶基因，该处的胺基酸 lysine与麸氨酸在多胜肽链的第342位置交换(Glu342Lys)；北欧血统白人每1，700人有1人是此一突变的同合子，因此血浆抗胰蛋白酵素值比正常低10%到15%。

Methods PCR-SSCP and PCR product cloning, sequencing were performed to detect mutation of p16 gene exon 2 in peripheral blood of 60 patients with arseniasis caused by coal-burning pollution,at the same time,PCR-based methylation assay was performed to analyze the methylation of p16 gene exon 1. Results No p16 gene exon 2 mutation was found in 60 cases.

采用聚合酶链反应-单链构象多态性分析和PCR产物克隆测序技术对60例砷中毒患者外周血中p16基因第2外显子突变情况进行检测，同时采用甲基化敏感的限制性内切酶方法对p16基因第1外显子甲基化情况进行分析。

Objectives: The purpose of this study is to analyse the point mutation of DYS1 in azoospermic patient and to find the relationship between point mutation and azoospermia.

用聚合酶链反应方法检测了染色体核型正常的200例无精子症患者基因组DNA中的DYS1基因，发现8例有DYS1的缺失。

Sequencing and mutation detection in collaboration with Dr. Dunlap have localized prd-4 mutation.

和美国 Jay Dunlap合作进行了测序和突变分析，获得了生物钟prd-4基因。

Objective To investigate the FECH gene mutation in a Chinese family with erythropoietic protoporphyria, to explore the relationship between gene mutation and clinical manifestations so as to establish a basis for the genetic diagnosis and treatment of erythropoietic protoporphyria.

目的 对一红细胞生成性原卟啉病家系进行基因突变研究，探讨基因突变与临床表现的关系，为进一步开展基因诊断和基因治疗奠定基础。

A novel mutation in the donor splice site of intron 1 of FECH gene is first reported in a Chinese family with EPP; this mutation may lead to a deficiency of FECH gene and serve as a molecular basis of development of erythropoietic protoporphyria.

报道一FECH基因第1内含子供体剪接位点的新突变，该突变可能引发FECH基因缺陷，是EPP家系中患者发病的分子基础。

Chemical mutagenesis can effectively create many new peanut genotypes. And appropriateconditions of induced mutation can increase mutation efficiency and develop peanut germless resources well.

化学诱变能有效的创造各种突变体，确定诱变的适宜条件能提高诱变效率，更好地拓展花生种质资源。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。