查询词典 mutation

Primary hepatocellular carcinoma is one of the most common neoplasms in China. Most previous experimental researches were against tumor cells which had characters of unable transmissibility, high heterotype and high mutation rate, so satisfied curative effects could not be obtained.

原发性肝癌是我国常见的恶性肿瘤之一，以往的实验研究多数针对肿瘤细胞本身，但瘤细胞具有遗传不稳定性、高突变率和高异型性等特点，因此、未能取得满意的疗效。

Results The Val383Ile mutation was found in the heterozygous state in two diabetic subjects and none in control subjects.

结果 病例组中发现2例为GLUT4基因Val383Ile突变的杂合携带者，对照组中未发现GLUT4基因Val383Ile突变。

Out of all P16 gene changes,4 were dot mutation,2 were deletion and 1 was heterozygous.

结果16例胰腺组织标本中有7例检测出存在着P16基因的改变，4例标本为点突变，2例标本为缺失型改变，还有1例患者存在着野生型与缺失型同时存在的杂和状态。

This factor is highly conserved in mammalian animals and only one heterozygous LIF mutation was reported to cause the infertility of women.

LIF在所有的哺乳动物中都具有高度的保守性，某些氨基酸在不同物种中保持不变。 LIF中29位氨基酸在所有的哺乳动物中都是Q。

Objective To investigate the mutation characteristics of paired box homeotic gene 9(PAX9) and mus-cle segment homeobox gene 1(MSX1) of patients with congenital oligodontia.

目的 探讨多数牙先天缺失患者的人类成对盒基因(PAX9)和肌节同源盒基因(MSX1)突变位点，为该疾病的病因学研究提供依据。

Because homeotic gene mutation and floral organ variation is a direct relationship,therefore the mutant application is the current functional genomics study developmentdirection. We discovered one mutant ah from line 458, which was a line ofthe twin-seedling strain W2555.ln this study, we have investigated the morphogenesisprogress, genetic analysis of mutant traits and molecular tagging of related gene.

目前，由于在水稻中发现的花器官突变体很少，所以对水稻花发育的研究主要是利用双子叶植物MAS-box基因的保守序列设计引物，在水稻基因组或者cDNA文库中筛选与双子叶植物花器官发育相对应的MADS基因，因为同源异型基因的突变与花器官的变异是直接对应的关系，所以突变体的应用是当前功能基因组学的发展方向。

High copies and the homoplasmic mutation in tumor, mtDNA mutations may be attractive diagnostic markers for some cancers.

由于肿瘤中mtDNA的高拷贝、同质性突变等特点，有人提出mtDNA突变有希望成为肿瘤早期诊断的分子标记。

Although Fan et al. observed that the milder COI mutation was retained through successive generations, it was always homoplasmic, so the ability to filter it out was never put to the test.

尽管Fan等人认为COI温和突变仍然在后代中保留下来，，由于它总是同质的，所以从不去筛选它们突变的能力。

In the current study, we have detected the mtDNA mutation in lung cancer, investigated the correlation between the mtDNA mutations and carcinogenesis, and explored the possibility of mtDNA mutations as a biomarker. We also analyzed the reasons for the homoplasmic mutations of mtDNA.

为了探讨mtDNA突变在肺癌发生中的意义、mtDNA突变在肺癌早期诊断中作为分子标记的可能性以及mtDNA多态性与肺癌易感性的关系，我们检测了肺癌mtDNA突变，分析了肿瘤中mtDNA同质性突变的形成原因。

Of other variants, the novel homoplasmic A4435G mutation absent in 164 Chinese controls is localized at 3' end adjacent to the anticodon, at conventional position 37 (A37), of tRNAMet.

实际上在A4435G和G11778A都有突变的细胞中可观察到tRNAMet稳态水平的有效降低，而在仅有G11778A突变的细胞中则不能。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。