查询词典 mutation

Subsequent molecular studies discovered that this mutation led to gain-of-function of GATA 2, partly blocking myelo-monocytic differentiation and resulted to acute transformation of CML.

随后的分子生物学研究结果提示该突变导致获得性GATA-2功能增强，部分阻滞了CML髓系祖细胞的分化，为慢粒发生恶性转化提供了重要的分子学证据。

However, the mutation of GATA site at -2948bp remarkably reduced the reporter gene activity driven by SV40 promoter, but not by ε-globin gene proximal promoter. To test whether those sites act synergistically, we mutated 2 of these three binding sites with different combinations.

然而，GATAb（在-2948bp的GATA位点）的突变明显地降低了SV40启动子介导的报告基因转录活性，但是对ε-珠蛋白基因启动子介导的报告基因表达却影响不大。

Objective To study G6PD gene mutation diversity in Yao and Han people in Guangxi and compare the genotypic frequencies.

目的 研究广西瑶族葡萄糖-6-磷酸脱氢酶(G6PD)基因突变特点，并与汉族作比较。

Ecological conditions in such a mutation has occurred has become a unique shape of the genetic characteristics of the bleaching with the law back to the green phenomenon and the characteristics of ammonia Glandless.

在这样的生态条件下发生的突变体形成了独有的遗传特性，具有规律性的白化返绿现象和高氨低酚的特征。

The results indicate that the material has no toxicity, no stimulation and mutation, and it does not cause hemolysis and hemopexis.

结果表明，HA/PDLLA材料无毒，无致突变性，不引起溶血和凝血。

To investigate the relationship between Arg778Leu mutation of ATPTB gene and clinical manifestation in hepatolenticular degeneration.

目的：探讨肝豆状核变性（Hepatolenticular Degeneration，HLD）患者ATP7B基因Arg778Leu突变型与临床表现之间的相关性。

The origin of the heterochromatic regions on the long arm of maize B chromosome was studied in two ways: the Southern signals of the CL-repeat; and its deletion, insertion, and mutation variants.

本研究分别以CL-repeat的南方杂合讯号以及因缺失、插入和突变造成的序列变异两个角度，来探讨玉米B染色体长臂远端异染色质(distal heterochromatin， DH)区的起源。

The origin of the heterochromatic regions on the long arm of maize B chromosome was studied in two ways: the Southern signals of the CL-repeat; and its deletion, insertion, and mutation variants.

中文摘要本研究分别以CL-repeat的南方杂合讯号以及因缺失、插入和突变造成的序列变异两个角度，来探讨玉米B染色体长臂远端异染色质(distal heterochromatin， DH)区的起源。

Analysis of double mutants between bro-1(bp133) and several heterochronic mutants showed that the proliferative seam cell division occurred at any stage was defective in bro-1 mutation background.

对bro-1和不同异时基因构成的双突变的细胞谱系分析表明在L2时期以外时期出现的增殖性分裂也可以因为bro-1基因的突变而缺失。

BACKGROUND: Retinitis pigmentosa is a group of commonest genetic blindness-inducing eyeground diseases, which have relative great heterogenicity in both heredity and phenotype. Pierce et al discovered a new retinal photoreceptor cell specific gene-RP1 in 1999, and also found in their following research that the mutation of this gene can induce autosomal dominant RP .

背景：视网膜色素变性(retinitis pigmentosa，RP)是一组最常见的遗传性致盲眼底病，在遗传和表型上均具有较大的异质性。1999年Pierce等发现了一个新的视网膜感光细胞特异基因--RP1，之后的研究发现该基因的突变可导致常染色体显性遗传RP(autosomal dominant RP，adRP)。

But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊！不用提了。提到肉，真是糟透了。