查询词典 mutation

Evolutionary models of senescence suggest that either a mutation deleteriously affecting older individuals will be selected against more weakly than one affecting younger individuals, or there are genes which benefit early reproduction which have deleterious effects later in the lifespan.

衰老的进化模型认为，或者一个影响较老个体的有害突变，比影响年轻个体的有害突变，受到更弱的选择对抗，或者对早期繁殖有益的基因在生命晚期有恶性影响。

ObjectiveAcute toxicity experiments and mutation experiments were conducted on mice with the flavonoids from the leaves of Dendrocalamus latiflorus.

目的利用麻竹叶黄酮进行了小鼠急性毒性实验和致突变实验。

The dermatic phenotype caused by R75W varied in extent among different nationalities, while this mutation consistently caused severe to profound bilateral sensorineural hearing loss.

在不同种族R75W导致的耳聋多为双侧重度到极重度感音神经性聋，而皮肤表型的严重程度有所不同。

objective to analyze the drug resistance of staphylococcus aureusand provide suggestion for clinical rational use of antibiotics.methods secretion of those neonates suffered primary skin soft tissue infection and admitted during june,2005 to december,2007 was cultured and 113 strains of staphylococcus aureus were detected.we used k-b diffusion methods to determine their susceptibility to the common used antibiotics.results resistance rates of staphylococcus aureus to ampicillin/sulbactam,penicillin-g and cefazolin were 14.2%,40.7%and 6.2% respectively; there was no vancomycin-resistant strain.conclusion the resistance of staphylococcus aureus is not a serious problem in neonatal dermatic soft tissue infection.local treatment is the major approach in clinic,while general anti-infection consisting mainly of penicillin and first generation cephalosporin is chosen to avoid resistance mutation of staphylococcus aureus resulted from abuse of antibiotics.

多重聚合酶链反应快速鉴别葡萄球菌及。。。乳腺脓肿分离到葡萄球菌的鉴定和药敏。。。目的探讨金黄色葡萄球菌的耐药性，指导临床合理用药。方法对我院2005年6月至2007年12月新生儿原发性皮肤软组织感染患儿的分泌物进行培养，共检出金黄色葡萄球菌113株，并采用kb纸片扩散法对其进行常用抗生素的药敏试验。结果金黄色葡萄球菌对氨苄西林/舒巴坦、青霉素g及头孢唑啉的耐药率分别为14.2%、40.7%和6.2%，未发现耐万古霉素金黄色葡萄球菌。结论在新生儿皮肤软组织感染中金黄色葡萄球菌的耐药问题并不十分严重，临床处理应以局部为主，全身抗感染治疗宜以青霉素及i代头孢类抗生素为主，避免过度使用抗生素加速金葡菌的耐药突变。

In this paper he pointed out:"One difference drawing most attention between the descendibility of humans and anthropoids is that humans have 46 (23 pairs) of chromosomes, and our close relative anthropoids have 48 chromosomes … Understanding if such recomposition of chromosomes is a prime cause of human evolution, or only is a secondary effect during mutation of descendibility, has great significance in biology".

遗憾的是， John Maddox 写这篇论文时他不知道中国的蒋春暄早在二十年前开创了该领域的研究已经获得重要的成果。

Chronic injury of Hepatic, immunologic response and the oxidized of DNA injury may cause gene mutation, carcinogenic gene;oncogene activated , tumor-suppressing gene devitalized, at last result in carcinogenesis.

本课题从基因及蛋白质两方面检测HDAC6在肝癌组织中的表达并探讨其与肝癌发生发展过程中相关的临床病理因素间的相关性，从而期望能够发现肝癌发病及发展和转移新的因素，为肝癌临床治疗提供理论依据。

The results of χ2 test showed that the frequencies of genotypes in different breeds were significantly different (P＜0.01).The frequencies of mutation genotypes in Yorkshire were significantly higher than Duroc and Landrace.According to the above results,we can speculate the difference of the frequencies of genotypes may be the results of long term choice pressure.

统计结果发现基因型频率分布与品种有关，大白猪突变基因型频率显著高于长白和杜洛克，本研究推测分布上的差异可能是由于长期的选择压力造成的。

It has been proved that TR mutation was related to dyskeratosis congenita, and TR could function as the template in telomere DNA synthesis.

并且对细胞分裂等细胞学事件必不可少，已证明TR 突变与先天性角化不良等疾病相关。

Ectodermal dysplasia ; DNA mutation analysis ; Sequence analysis ; DNA ; GJβ6gene

外胚层发育不良症； DNA突变分析；序列分析； DNA ； GJβ6基因

Objective: To identify EDA gene mutation in a pedigree of Han nationality in Xinjiang with X-linked hypohidrotic ectodermal dysplasia so as to provide a basis for gene and genetics diagnosis of this disorder.

目的：检测一新疆汉族X连锁少汗性外胚叶发育不全家系引起先天缺牙的EDA基因突变，为XLHED综合征的基因和遗传学研究提供理论依据。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。