查询词典 mutation

Objective: To detect the deletion and point mutation of WW domain containing oxidoreductase exons 6-8 in human primary cultured lung carcinoma cells and the relationship with clinical pathological indices thereof.

目的：探讨肺癌原代培养细胞中的抑癌基因WWOX第6~8外显子的缺失及点突变情况及其与临床病理指标的关系。

Objective To study the relationship between K-ras mutation in pancreatic juice accompanying by serum CA 199 level and recurrence of pancreatic carcinoma.

目的 探讨胰液中K-ras 12密码子点突变联合血清CA 199检测与胰腺癌病程的关系。

Objective To investigate the diagnostic significance of detecting p16 aberrant methylation and K-ras gene mutation in pancreatic juice for pancreatic cancer.

目的 探讨胰液中K-ras基因突变和p16基因启动子区5′CpG岛甲基化联合检测在胰腺癌诊断中的价值。

Objective To evaluate the value of pancreatic juice in cytologic examination and PCR-SSP in detecting K-ras gene mutation for diagnosis of pancreatic carcinoma.

目的 评价胰液细胞学检测与聚合酶链反应―顺序特异性引物检测K-ras基因点突变诊断胰腺癌的价值。

K-ras mutation in pancreatic juice and serum CA 199 level are effective in dictators for recurrence and prognosis of pancreatic carcinoma. The analysis of muliti-gene is more valuable than that of single.

联合胰液中K-ras 12密码子点突变及血清CA 199检测可作为判断胰腺癌术后复发的有效指标，多因素分析对胰腺癌术后复发的判断更有价值。

Objective: To analyze the BRCA1 mutation from the paraffin embeded tissue of 231 patients with breast cancer in southern China.

目的：研究中国妇女BRCA1基因突变与遗传性、家族性和早发性乳腺癌的关系。

P. denasta harbored the three chlorotypes, two of which were characteristic of its two parental species respectively. The third chlorotype was extensively distributed in seven of the ten P. densata populations analyzed, and might represent a mutation type or have been derived from an extinct parent. Population differentiation of P.

TT和GC分别是油松和云南松种特异性叶绿体单倍型，而在高山松群体里则三种单倍型均有分布，而且TC单倍型广泛地分布在7个杂种群体中，该单倍型很可能来源于点突变或第三个已灭绝的亲本。rbcL基因检测到的高山松群体分化系数很高（G〓=0.533）。

Domenstic and abroad academicians have disclosed the influence mechanism of these factors from different aspects, including the gene polymorphism and gene mutation in genetics, which are a susceptible factor for cardiovascular complication in type 2 diabetes patients; the dysfunction of endotheliocyte, the metabolic disorder of lipid, and dysfunction of vascular smooth muscle, which can lead to the formation of arteriosclerosis;the formation of immune complex,which can also accelerate the destruction of artery paries;the sctivation of protein kinase C and the dysfunction of platelet, which may ultimately result in the formation of thrombus and influence the function of cadiac muscle cells.

其中主要包括：遗传学方面的基因多态性和基因突变，二者均是2型糖尿病合并心血管疾病的一个易感因素，内皮细胞功能障碍、脂质代谢异常及血管平滑肌细胞功能异常均可导致动脉粥样硬化的形成；免疫复合物的形成可加速动脉壁的破坏；蛋白激酶C的激活及血小板功能受损最终导致血栓形成并影响心肌细胞的功能。

The mutation of Parkin gene is one of the pathogenesis of early-onset Parkinson's disease.

Parkin基因突变是早发性帕金森病患者发病原因之一。

To detect the mutation of PINK1 gene in Chinese patients with early onset Parkinsonism by using DHPLC.

应用DHPLC技术对100例EOP患者进行PINK1基因突变筛查，对DHPLC筛查发现异常的PCR扩增片段进行DNA直接测序和分析。

For a big chunk of credit-card losses; the number of filings (and thus charge-off rates) would be rising again, whether

年美国个人破产法的一个改动使得破产登记急速下降，而后引起了信用卡大规模的亏损。

Eph. 4:23 And that you be renewed in the spirit of your mind

弗四23 而在你们心思的灵里得以更新