查询词典 mutation

Deletion of exon 5, 8 was observed in cutis primary T cell lymphoma and no mutation was found. The abnormality may play a role in the pathogenesis of the cutis primary T cell lymphoma.

原发性皮肤T细胞淋巴瘤中存在FHIT基因外显子5和8的异常缺失，这种异常转录可能与该病的发生有关。

In the 1980s in the medicine circles of China, there was a blind spot in? Zhu Changqing' parents visited all the hospitals in Shanghai in order to find out the pathology. At last, they searched the cyclopedia for the information and found the brief explanation less than 100 words. It was said that the cause of this disease was still a mystery, maybe resulted from gene mutation, and till now there was no efficient means to treat it.

80年代的中国医学界，对神经性肌肉疾病的认识是一个盲点，朱常青的父母亲为了了解孩子的病因，跑遍了上海所有的医院，请教了众多的专家，最后还是仅仅百科全书里找到不足百字的词条介绍，大意是这种病的病因还不是很清楚，可能是由基因突变引起的，目前尚没有找到治疗的有效手段。

In contrast, cancer cells lacking functional P53 would be expected to be sensitive to viral replication and subsequent cytolysis. However P53 defections wildly exist in most of human cancer cell, deletion of E1B-55kD gene can make the adenovirus target at p53 mutation tumor cell.

以往的研究表明，大部分人类肿瘤中均存在p53基因突变，因此E1B55kD蛋白缺失的重组病毒只能在P53功能异常的肿瘤细胞中复制，而在正常细胞中该重组病毒由于缺乏对抗P53蛋白的病毒产物，不能有效复制，因此具有肿瘤靶向治疗的特点。

For example, this algorithm can be used to check the DAG in Genetic Algorithm when the mutation happened.

例如在利用遗传算法学习贝叶斯网结构的过程中，变异后的网络结构可使用增量式拓扑排序进行环路检测。

These skew reflect mainly those in protein coding sequences, which are driven by asymmetric mutation pressures during replication and transcription (notably asymmetric cytosine deamination) plus subsequent selection for preferred structures, signals, amino acid or codons.

这些不对称性主要反应在蛋白质编码序列上，并且主要是受到复制与转录期间复制双股之间的不对称突变压力加上之后为了偏好的结构、信号、胺基酸或转录子的筛选所驱使。

Uracil also can be introduced by hydrolytic deamination of cytosine which paired with guanine. Highly mutagenic dU:dG mispair may cause a C→T transition mutation upon replication if it was not repaired.

另一种可能则是由胞嘧啶(Cytosine； C)发生自发性或氧化脱胺反应而形成尿嘧啶与鸟粪嘌呤的配对错误。

The codingoperator expresses the genes with N-decimal system floating numbers, and then the genes are divided into integer part and decimal part. The two parts are encoded into chromosomes respectively. The corresponding selection, crossover and mutation operators are designed with the theory of symbol encoding and the properties of N-decimal system floating numbers.

该编码算子首先将每个基因值用N进制的浮点数表示，然后将其分为整数部分和小数部分，分别重新编码组成染色体；相应的选择、交叉、变异算子采用符号编码的思想，充分利用N进制浮点数的特点进行设计。

BRAF gene mutation has been confirmed to be closely related to the dedifferentiation of papillary thyroid carcinoma.

研究证实，BRAF基因突变与甲状腺乳头状癌的失分化现象密切相关。

September 15, Lehman Brothers filed for bankruptcy protection, sub-loan crisis of mutation into a financial tsunami, inflation may be reversed to deflation, the monetary policy shift, therefore, capital growth has become top priority.

9月15日，雷曼兄弟申请破产保护，次贷危机突变成金融海啸，通货膨胀可能逆转为通货紧缩，货币政策因此转向，保增长成为首要任务。

Also,a web server of RNA deleterious mutation analysis is implemented.

并实现了RNA有害突变预测与分析的Web计算。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。