查询词典 mutation

His concept is that you use the dugs which may induce mutation as early as several months or sometimes several weeks, that's why he has to check the DNA mutations, but there are now some drugs available who are OK for 5 years. If so, why you have to worry about mutation by performing expensive DNA frequency.

Keeffe教授的概念是指如果你所使用的药物是在用药几周或者几个月后就会引起突变的话，在这种情况下就需要检测HBV DNA，而对于5年耐药率都很低的药物来说，就没有必要如此频繁地进行昂贵的检测了。

The novel mutation Y271H is the disease-causing mutation in the hereditary multiple exostoses family.

EXT1基因的Y271H杂合突变是导致该家系发生多发性外生性骨疣的致病突变。

All 21 exons with flanking intronic sequences, as well as a 263 bp fragment of the 5" flanking region, of GARS-AIRS-GART gene, were screened in the same five populations, by the method of PCR-SSCP analysis, combined with sequencing reactions. We detected 10 SNPs, C-179T from 5" flanking region, A5669G form exon 3, C6545Afrom exon 4, A7777G from intron 4, G10854T, C10867T, G10898T from intron 6, A16197G from intron 11, C21228T from intron 14, and C29686T from exon 21. These ten polymorphic sites were nominated as GARS1, GARS2, GARS3, GARS4, GARS5, GARS6, GARS7, GARS8, GARS9, and GARS 10, respectively. The mutation of C D A at GARS3 was a non-synonymous mutation, wh

其中外显子4中的6545处的c~A突变导致对应的氨基酸序列中的第173位氨基酸发生变异：天冬氨酸一谷氨酸；10个SNP位点依次命名为：GARSI、GARSZ、GARS3、GARS4、GARSS、GARS6、GARS7、GARSS、GARSg、GARS 10；(2)10个SN'P位点在不同的鸡种中的基因型分布差异显著(P.05)，进一步的方差分析显示，GASRI位点以及GARS3位点与肌肉肌昔酸含量之间存在着显著的关联；(3)在所检测的5个群体中GARsl位

The check of mutation of video camera lens that offerred a kind to be based on BP nerve network newly calculates a standard, this algorithm chooses pattern plate to match poor cent and histogram 2 times 2 times to differ cent to serve as a feature, those who use nerve network from organization, self-study mutation of camera lens of implementation of ability of be used to detects, detect in order to flash next will raise detected dependability.

提出了一种新的基于BP神经网络的视频镜头突变检测算法，该算法选取模板匹配二次差分和直方图二次差分作为特征，利用神经网络的自组织、自学习能力实现镜头突变检测，然后以闪光检测来提高检测的可靠性。

The group uses Big Blue transgenic animals and cell lines to study the mutagenic effects of mutagens, the relation between DNA damage and mutation, the effects of aging and diet on mutation.

该集团使用大蓝鼠转基因动物和细胞系来研究诱变剂的诱变效应，脱氧核糖核酸损伤和突变的关系，生物突变中年龄与饮食的影响。

Objective To study the effects of 20/21 bp partial deletion mutation (from nt 1 748 or nt 1 747 to nt 1 767) in the core promoter region of hepatitis B virus genome complicated by precore stop condon mutation at nt 1 896 on the expression of the viral antigens.

目的为研究乙型肝炎病毒核心启动子20/21bp部分缺失(nt1748/1747至nt1767)及同时存在的A1896点变异对病毒抗原表达的影响。方法利用前期构建的HBV全基因的重组载体转染HepG2细胞后，对病毒抗原进行ELISA检测及Western-blotting分析。

The aim of this study was to investigate the risk of cirrhosis associated with genotype, precore stop codon G1896A mutation and A1762T/G1764A double mutation in the basal core promoter of hepatitis B virus.

本研究乃以前瞻性世代研究法探讨B 型肝炎病毒B、C基因型、precore stop codon G1896A 突变和basal core promoter A1762T/G1764A 双突变对於发生肝硬化的影响。

Male sibs who inherit the mutation will be affected ; female sibs who inherit the mutation will be carriers and will usually not be affected .

继承突变的同胞兄弟将成为患者；继承突变的同胞姐妹将成为携带者，通常不会发病。

There were two genotypesin China Merino fecundity sheep,the BB and B+ mutation genotype was superior in Chinese merino fecundity sheep,the ewes with genotype BB and B+had 4.0 and 3.5 ovulations,genotype ++ had 1.56 ovulations averagely,The BB and B+ mutation genotypes were 2.44(P.01)and 1.94(P.01)ovulations more than with genotype ++ in the Chinese merino sheep.

绵羊的多胎是绵羊业多产、高产的基础。一般来说，家畜的繁殖性状是受多基因控制的数量性状，传统的选择方法对其遗传进展的改良是很慢的，世代间隔长。分子标记辅助选择为解决这一问题提供了新的方向和契机。

But when his group stratified the cohort by mutation status, they observed differences in risk reduction."These results also generate the hypothesis that the protection conferred by risk-reducing salpingo-oophorectomy against specific cancers may differ between carriers of BRCA1 and BRCA2 mutations," Dr. Kauff told attendees."We found that it is highly protective against BRCA -associated gynecologic cancer in both 1- and 2-mutation carriers." And in breast cancer, his team observed a protective effect in BCRA 2 mutations.

当他的团队统计研究对象的突变状态时，他们观察到风险降低的差异性；Kauff医师向与会听众表示，这些结果也产生了藉由风险降低的输卵管卵巢成形术，对特定癌症所提供的保护效果或许会因BRCA1和BRCA2载体突变而有差异的假设；我们发现对这两种载体突变可以高度有效地对抗BRCA有关的妇科癌症；至于乳癌，他的团队观察到在BCRA2突变有保护效果。

In the days of sailing vessels the crew were afraid they would be becalmed on the ocean.

在使用帆船的时代，船员们担心他们会因为无风而无法在海洋上航行。

As long as foreign donors pay the PA's salary bill, few expect a new intifada.

只要外国继续为巴权力机构的薪水买单，希望发动新暴动的人便寥寥无几。