查询词典 mutagenic

The fungchi ingredient that was used mistakenly in the dietary regimen was thought to be the main cause of the nephropathies. It contained aristolochic acid that was believed to be strongly nephrotoxic, mutagenic and carcinogenic.

在事发之瘦身诊所减肥处方中所误用的防己中药被认为是引起肾病变的主因，其含有具强烈肾毒性、致突变性与致癌性的马兜铃酸。

According to the results of agronomic traits and isoenzyme analysis, 20Gywas screened as the suitable dose for two varieties of Polianthes mutagenic L.

经农艺性状及同工酶分析，初步筛选出2个晚香玉品种的适宜辐照剂量为20Gy。

The screening of high tannase producer and mutagenic effects of Aspergillus niger 9701 with low N + ions implantation were studied.

研究了单宁酸酶高产菌株的选育以及低能N+离子注入黑曲霉 970 1 (Aspergillusniger 970 1 )的诱变效应。

For long-term use of large dose,it still need further research such as the chronic toxicity tests 、 mutagenic tests (Ames test, micronuclei test and spermatozoon teratism test).Key words: Xin xiebai powder, acute respiratory distress syndrome, experimental study, therapeutic effects, Acute toxicity test

新泻白散的急性毒性实验证实了其安全性，但长期大剂量的使用，还有待于通过长期毒性实验、三致实验等毒理方法的进一步研究。

Above results showed that minced Cr-containing fish meat has no mutagenic effect and is save for feeding genetic- toxicologically .

上述三项检测结果表明：铬对鱼无致突变作用，从遗传毒理学角度认为食用是安全的。

Reactive oxygen species causing DNA oxidative damage comes from two kinds of ways:one is from cellular normal physiological metabolism;the other is from outer environment.Redox-sensitive green fluorescent protein was expressed in Saccharomyces cerevisiae.Recombinant cells were evaluated in monitoring the changes in the redox state of living cells when challenged with toxicologically relevant metal ions NaAsO_2 or Pb(NO_3)_2 by measuring emission intensity at 510 nm with a Hitachi F6500 fluorescence spectrophotometer,roGFP expressed in yeast responded not only to typical membrane-permeant oxidants H_2O_2 and reductants DTT,but also to toxicological metal ion-induced intracellular redox changes in a dose-dependent manner.Moreover,exposure of yeast cells to NaAsO_2 or Pb(NO_3)_2 at concentrations that induced redox changes reported by roGFP caused up to 2～3 fold increases in DNA mutation frequency.This mutagenic effect was largely caused by oxidative stress since blocking the production of hydryl radicals with thiourea significantly reduced the mutation rate as well as delayed the cell death.

本文将对氧化还原状态变化敏感的绿色荧光蛋白roGFP1-R12，在酵母细胞中实现了多拷贝强表达；荧光扫描经强氧化剂H_2O_2和还原剂DTT以及环境中重金属NaAsO_2或Pb(NO_3)_2处理后的酵母细胞悬液，测定510 nm处的荧光发射强度结果显示，表达的绿色荧光蛋白对氧化还原水平敏感，且在510 nm处的荧光强度与一定的重金属浓度呈正相关，即roGFP1-R12在510nm处的荧光发射值随重金属浓度的增高而增强，从而说明重金属对细胞的毒性在一定程度上很可能是通过破坏细胞内的氧化还原平衡发生作用；同时通过该绿色荧光蛋白对胞内氧化还原状态变化的响应情况可以来实时检测环境中的重金属；遗传学的点突变频率及致死率实验数据表明，重金属能导致菌体的点突变频率和致死率升高，且活性氧的清除剂巯基脲能明显降低这种点突变和致死率，说明由重金属引发的这种点突变和致死效应在很大程度上是依赖于重金属对细胞诱导产生的氧化胁迫。

Animals in each group growth were good. No abnormal phenomenon was observed. ConclusionThe Trollius Beverrage's MTD of mice and rats was greater than 20000mg/. It was concluded that the product had no toxicity. The result of mutagenic test was negative and no abnormal phenomenon was observed after feeding for 30 days.

结论金莲花露对两种性别的大、小鼠的MTD均大于20 000 mg/，说明该产品属实际无毒物；三项致突变实验结果阴性；大鼠30 d喂养实验各项指标均无明显异常。

Mutagenic and antimutagenic effects of NaHSeO3 were investigatcd with Oda'sSOS/Umu chromotest,a few alterations were noticed.

亚硒酸氢钠（NaHSeO3）的致突变和抗突变作用尚无定论，本文应用稍加修改的SOS／Umu显色试验对其这方面的作用作了研究。

Our results suggest that coden 12 of the H-ras oncogene may be a specific target for the mutagenic activation by tobacco smoke, and smoking is an important factor in the induction of H-ras oncogene mutation.

提示H-ras基因可能是被烟草激活的一个特殊位点，吸烟是导致H-ras基因突变的重要因素。

According to the invention, the natural substances in question are selected from: hydroxy-cinnamic acids and the esters and depsides thereof; plant phenols which can be derived from hydroxy-cinnamic acids; polymers of hydroxy-cinnamic alcohols; other natural substances of plant origin which have anti-mutagenic and aromatising properties and are combined with anti-oxydant vitamins or with the precursors and/or derivatives thereof; and other anti-oxidant vitamins which are made to form complexes with eucaryotic cell cultures.

按照本发明，这些天然物质选自羟基肉桂酸及其酯和缩酚酸、可以由羟基肉桂酸衍生得到的植物酚、羟基肉桂醇的聚合物、具有抗诱变性和芳化性质的并且与维生素合用的其他植物源天然物质、以及与真核细胞培养物络合的其他抗氧化性维生素。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。