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Cerebrovascular diseases,characterized by high incidence and mortality,represent one of the most frequently occurred neurological diseases clinically,so it is of vital importance to instruct catechumen to precisely and systematically grasp related knowledge ranging from its pathogenetic mechanisms,clinical manifestations to treatment and prognosis in a short period.

者已从教学手段、教学内容和教学管理体制等方面做了一定的探索和尝试【，但由于多数脑血管病从发病到预后有其内在的特点，且由于我国现有医疗状况的制约，临床初学者尚难在短时间内充分、系统掌握脑血管病的病理发生机制、临床表现、治疗及预后。

Glutathioneis a special derivant of amino acid,presents in most plants,animals and microbes,plays a vital role in organisms.

谷胱甘肽是一种非常特殊的氨基酸衍生物，广泛存在于动、植物细胞，在生物体内有许多重要的生理作用。

As the most important inhibitory neurotransmitters in the central nervous system, the concentration change of GABA plays a vital role in neuronal excitory changes and abnormal discharge.

GABA作为中枢神经系统最具代表性的抑制性神经递质，其浓度的变化在神经元兴奋性的改变、异常放电的过程中起着举足轻重的作用。

Glioma is still one of refractory disease in the neurosurgical field; the development of new primary and adjuvant treatment is vital. Recently, the gene therapy of glioma is developed rapidly and there are many methods about the gene therapy that include: suicide gene therapy, immunologic gene therapy, drug resistangce gene therapy, angiostatin gene therapy and so on. The sucide gene therapy is the most potential approach of antitumer, these nonmammalian genes encode enzyme that convert nontoxic prodrugs into highly toxic metablites. Cells transfected with suicide genes are targeted for specific negative selection, witch can be induced by administrtion of the corresponding produg. Among the enzyme/produg combinations, two of the best characterized system are herpes simplex virus thymidine kinase /ganciclovir and Escherichia coli cytosine deaminase /5-flourocytosine (5-FC). The formor can convert the antiviral nucleoside analogs acyclovir , ganciclovir to their nucleoside monophosphate derivatives, the monophosphate forms are subsequently phosphorylated by endogenus cellular kinases to triphosphates, these molecules are potent inhibitors of DNA synthesis.

近年来脑胶质瘤的基因治疗发展迅速，应运而生的方法有自杀基因、免疫基因、多药耐药基因以及抗血管生成基因等，其中自杀基因被认为是最有前景的基因治疗方法，它又称病毒介导的酶／药物前体疗法，是利用转基因技术将哺乳动物细胞中所不含有的自杀基因转入到哺乳动物肿瘤细胞中，该基因表达的产物可将无毒的药物前体转化为毒性药物，从而选择性杀伤该肿瘤细胞，常用的自杀基因有单纯疱疹病毒-胸苷激酶基因和大肠杆菌胞嘧啶脱氨酶基因，前者催化无毒性抗病毒核苷类似物如丙氧鸟苷、无环鸟苷等成为单磷酸核苷衍生物，然后在内源性细胞激酶作用下转化为具有明显毒性的三磷酸核苷，作为DNA合成链的终止剂和DNA合成酶的抑制剂，干扰细胞DNA的合成；后者编码的胞嘧啶脱氨酶可催化5-氟胞嘧啶（5-FC）脱氨成为5-氟尿嘧啶（5-FU），然后代谢为有毒性的5-氟尿嘧啶-5′三磷酸（5-FUTP）和5-氟-2′脱氧尿嘧啶-5′磷酸（5-FdUTP），5-FUTP通过与UTP竞争性结合而抑制mRNA和tRNA的合成，5-FdUTP则作用于胸苷合成酶，导致TMP衰竭而阻止DNA的合成，最终诱导肿瘤细胞凋亡。

Under the distinguish environment it is vital for CEIEC to re-carve out the business by making out the development strategy resulted from the re-location with an eye to temporizing the trend, which is the most important and urgent question and subject for discussion.

因此，重新定位，制定发展战略，参与国际竞争，迎接挑战，是摆在 CEIEC 面前须刻不容缓予以解答解决的重大问题和课题。

I've written before that approximately 2/3 of the earth's tillable soil is completely devoid of Selenium, a vital trace element and power mineral required not only for the production of SOD but also one that is a powerful immune booster, cancer fighter and longevity mineral too, that most people have virtually no selenium in their diet which is another great reason to make sure that you're taking the true RDA of 200mcg per day.

我写此之前，大约有2 / 3地球的耕地土壤是完全缺乏硒，一个重要的微量元素和矿物质的权力，不仅需要为生产的SOD ，而且还一说是一个功能强大的免疫强心针，癌症战斗机和长寿的矿产太，大部分人都几乎没有硒在他们的饮食，这是另一个重要原因，以确保您以真正的推荐的每天

The home education accepts the education as the life most early, affects the time longest one fundamental mode, is playing the very vital role in younger generation's development process, is the school edition is unreplaceable....

家庭教育作为人生接受教育最早，影响时间最长的一种基本形式，在年轻一代的成长过程中起着非常重要的作用，是学校教育不可替代的。。。。

Corporate opportunity doctrine is one of the most important rules in corporation law of common law countries, and it purports to protect the interest of the corporations, by imposing the directors and managers the duty of not usurping corporate opportunity, and safeguarding the business opportunities belonging to the corporation and vital to its development.

摘要公司机会原则是英美国家公司法中一项重要的法律制度，它通过确立公司董事和管理者篡夺公司机会的禁止性义务，保护公司赖以生存和发展的商业机会，达到维护公司利益的目的。

Most of our urgencies relate to small things in our life, but they eat away our vital living.

我们最迫切与我们生活的小东西，但我们切身生活蚕食。

Between criterion and freedom, the vital moral education emphasizes the life state which is the interdependent of individual life and colony life, and the suitable between body and spirit, and expects to go off the predicament that criterion as the most important thing arrogates freedon life.

在规范与自由之间，生命化德育强调的是群己相依、身心相宜的生命状态，以期从规范至上对生命自由的僭越中走出。

Plunder melds and run with this jewel!

掠夺melds和运行与此宝石！

My dream is to be a crazy growing tree and extend at the edge between the city and the forest.

此刻，也许正是在通往天国的路上，我体验着这白色的晕旋。