查询词典 monozygotic twins

We investigated the characteristics of visual evoked potentialsof the eyes with normal visual acuity in 84 children of whom 20 were normal,28 of anisometropic amblyopia,8 of ani-sometropic amblyopia already cured, 8 pairs of monozygotic and 6 pairs of dizygotic twins with ambly-opia.

对84例儿童正常视力限的视觉诱发电位（visualevokedpotential，VEP）进行了分析，其中正常儿童20人，屈光参差性弱视儿童28人，治愈的屈光参差性弱视儿童8人，单卵双生子8对，双卵双生子6对。

In pairs of monozygotic and dizygotic twins.

相关的对单卵和双卵孪。。

RESULTS: Of those recruited, 1114 twins were identified in the analysis, including 355 monozygotic and 202 dizygotic twin pairs.

结果：在选取的研究对象中，对1114名双生子的结果进行了分析，包括355对单合子双生儿和202对双合子双生儿。

The difference of concordance between monozygotic and dizygotic twins suggested that the susceptibility of MS was affected by genetic factors.

单卵双生子与异卵双生子的患病一致性差异表明，遗传因素在MS发病中起一定作用。

Objective: It was the aim of this study to assess the role of birth weight in the development of myopia using a large cohort of Caucasian monozygotic and dizygotic twins that took part in the Genes in Myopia twin study.

目的：近视眼基因双生子研究通过大样本的高加索人种单卵和双卵双胞胎对出生体重在近视发生中的作用进行评估。

RESULTS. A total of 1224 twins (690 monozygotic and 534 dizygotic ) between 18 and 86 years of age were recruited into the GEM study. A total of 96 twins (96/347 = 27.7%) comprising 50 MZ and 46 DZ twins were first prescribed optical correction for myopia at the age of 18 years or older.

结果 18至86岁的1224对孪生子（单卵双生690对和双卵双生534对）参与了这项近视基因研究。96对孪生子（96/347 = 27.7%）包括50对单卵双生和46对双卵双生子在18岁以后第一次进行了近视视力矫正。

Studies comparing concordance rates for major depression between monozygotic and dizygotic twins suggest a heritability of about 37%, 5 which is much lower than the heritability of bipolar disorder or schizophrenia.

在单合子卵双生和双卵双生之间的严重抑郁的研究比较一致率，提示大约有 37%的遗传可能性，明显低于双阳性精神障碍或精神分裂症的遗传率。

While the effect of IGF on the ovaries likely involves fraternal, or dizygotic, twins, they were not distinguished from identical, or monozygotic, pregnancies in this study.

在本研究中，虽然IGF作用于卵巢可以引起异卵或双合子双胞胎妊娠，但是这种妊娠不能和同卵或单合子双胞胎妊娠相区别。

Majority of acute leukemias in infant, either acute lymphoblastic leukemia or acute myeloblastic leukemia, posses a chromosomal translocation affecting the 11q23 chromosome region which specifically inoles the mixed-lineage leukemia gene.1-3 Most pediatric leukemias with MLL rearrangement clearly hae a remarkably short latency.1,4 MLL gene rearrangement is also associated with secondary leukemias of patients preiously treated with the topoisomerase II inhibitors.4 The latency of these secondary leukemias is similarly ery short.4 Of note, the concordance rate of leukemia with MLL rearrangement in infant monozygotic twins approximates to 100%,1,4 and identical breakpoint in the MLL gene was shared in these pairs of identical twin infants with concordant ALL.1,4 Moreoer, the unique and clonotypic MLL fusion gene was detectable in neonatal blood spots for Guthrie cards from non-twined indiiduals who subsequently deeloped ALL.1,4 These obserations indicate not only that MLL fusion is generated in utero but also that MLL fusion proteins could be capable of inducing leukemic transformation with few, if any, secondary mutations.2,3,4 Greaes et al speculate that an MLL fusion protein somehow promotes rapid transition to full-blown disease in patients ia ery rapid clonal expansion, genetic instability, or inhibition of DNA damage repair.4 In general, for clonal expansion of malignancies, tumor cells often hae acquired strategies that escape immune sureillance of the hosts.5,6 Immune escape mechanisms also contribute to the failure of graft-ersus-leukemia effect after allogeneic hematopoietic stem cell transplantation.7 Therefore, leukemia cells could acquire some immune escape mechanisms during leukemogenesis.

绪论 绝大多数的婴儿白血病，不管是急性淋巴性白血病或是急性骨髓性白血病，在染色体11q23部位有染色体易位的情况；这个部位的染色体易位牵连了混合谱系白血病基因。大多数具有MLL基因重排的儿童白血病潜伏期明显短很多。MLL基因重排也和经拓扑异构酶II抑制剂治疗后的继发性白血病有关。这些继发性白血病的潜伏期类似地都非常的短。很重要的是，单卵双胞胎婴儿同时患有或同时免于MLL基因重排阳性的白血病的一致性接近100%；并且同样患有ALL的同卵双胞胎的MLL基因的断裂点是一致的。而且，这种独特的克隆特异性的MLL融合基因能够从那些得ALL的非双生个体出生时的血斑标本中检测到。这些发现表明MLL融合基因产生在胎儿还在子宫的是后，而且MLL融合蛋白能过和其他的基因突变一起诱导白血病的产生。Greaes 等推测MLL融合蛋白在某种情况下同过快速克隆增殖，遗传的不稳定性或是DNA损伤修复的抑制促使疾病迅速地全面爆发。恶性肿瘤细胞的克隆增殖通常已经获得了逃避机体免疫监视的能力。免疫逃避机制也归因于异体外周血干细胞移植后移植物抗白血病作用的失效。所以，白血病细胞在白血病的产生过程中可能获得了某些免疫逃脱机制。

Preious chromatographic analysis of colonic mucins from monozygotic twins with inflammatory bowel disease suggested a genetic mucin alteration in ulceratie colitis.

先前对患有炎症性肠病的单卵双生患者结肠粘蛋白的色谱分析表明溃疡性结肠炎存在有粘蛋白的遗传性改变。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。