查询词典 mononuclear cells

Keywords: bone marrow mesenchyme stem cells,bone marrow mononuclear cells,autoplastic transplantation,coronary heart disease,hepatic injury

中文关键词：骨髓间质干细胞；骨髓单个核细胞；自体移植；冠心病；肝损伤

Objective: To research the effects of traditional Chinese medicine and autoplastic transplantation of bone marrow mononuclear cells or bone marrow mesenchyme stem cells on the serious disease, such as myocardial infarction , hepatic injury and hepatic fibrosis, etc. Methods and Results:(1) MI was induced in a percutaneous swine by embolization in coronary artery.

为了探索中药和干细胞移植对心肌梗死、肝损伤及肝纤维化等重大疾病的治疗作用，进行了如下研究：（1）利用心导管技术，建立了冠状动脉栓塞中国小型猪心肌梗塞模型，利用此模型，观察中药复方双龙方与自体骨髓单个核细胞对心肌梗塞的治疗作用及对心功能的影响。

bone marrow mononuclear cells composite bone xenograft can restore caput femoris necrosis, and nearly have the same effects as bone marrow stromal cells.

骨髓单个核细胞确有修复坏死股骨头的效果，且与骨髓基质干细胞修复效果相似。

AIM: Peripheral blood mononuclear cells were cultured in vitro to study the effect of gossypol, a polyphenolic antifertility agent, on the activation of normal human T cells.

目的：以体外培养的人外周血单个核细胞为材料，研究多酚类抗生育药物棉酚对正常人外周血T淋巴细胞体外活化作用的影响。

By retrovirus vector the foreign mdr1 gene could be efficiently transferred into bone marrow mononuclear cells of mouse in vitro, and it was confirmed that mdr1 gene was expressing stably and effectively in cells; in short terms there is no significant influence on the bone marrow MNC by transfection of mdr1 gene,but in the long run(in our study we had surveyed 2 months),there is a decline in the expression of apoptosis factor Bax in the MNC which transfected by mdr1 gene,in favour of the recovery of the receptor mouse;on the other hand it also poses a blance problem between multiplication and apoptosis in the process of receptor hematopoiesis after transplanting HSC which was transfected with mdr1 gene.

通过逆转录病毒载体可在体外将外源性mdr1基因转入小鼠骨髓单个核细胞中，转染的mdr1基因能整合到骨髓单个核细胞基因组中并有功能性表达；mdr1基因转入小鼠骨髓单个核细胞在移植后短期内对受体造血细胞没有显著影响，但从长期看来(本研究观察2个月)转染了mdr1基因的造血干细胞的凋亡因子Bax表达降低，更有利于受体鼠造血的恢复；另一个方面它也同时提出一个问题，即mdr1基因转染造血干细胞在回输受体后造血过程的增殖凋亡平衡。

Results In the subendocardium of the left ventricle,apical part and interventricular septum,the pathologic changes of degeneration and necrosis were found out in some bigger size of point or rope type separately,in which the filtration of lymphocyte and mononuclear cells were seen in great quantities.The myocardial cells presented granular denaturation and myofibril lysis.

结果 实验组大鼠心肌在左室壁内膜下、心尖、室中隔部位出现明显坏死等改变，病变呈灶状或条索状分布，涉及范围较大，有淋巴细胞和单核细胞浸润，心肌细胞呈颗粒变性，肌原纤维凝聚、崩解，部分肌纤维溶解。

Further characterization of perfusate mononuclear cells showed an increased proportion of CD4CD25CTLA4 T cells compared with healthy control blood.

灌流液单核细胞的更多特征表明与健康个体的对照血液相比CD4CD25CTLA4 T细胞比例增加。

Results After induction by VEGF or PDGF for 1 week,most of adherent mononuclear cells became round and small, while few grew into spindle-shaped cells.

结果新鲜脐血分离单个核细胞培养1周后贴壁细胞的EPCs特异的Dil标记乙酰化低密度脂蛋白鉴定为80％阳性。

As an ultima ratio , the patient underwent an intravitreal injection of autologous bone marrow-derived stem cells obtained by isolating mononuclear cells from 100 ml of bone marrow.

该患者接受了玻璃体内自体骨髓源性干细胞移植，结果显示，玻璃体内自体骨髓干细胞移植技术上是可行的，且治疗没有显示任何副作用。

Endothelial progenitors cells were derived from mononuclear cells of peripheral blood, which can be induced into endothelial cells at specific conditions.

成人外周血中的内皮祖细胞来源於单个核细胞，在一定条件下可以诱导分化为内皮细胞。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。