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Result The parasites synchronized with sorbitol in vitro was treated by daphnetin and daphnetin-Fe complex.

经瑞香素(100μmol/L)作用1、2、3和4h后RNR活性分别被抑制7%、51%、69%和75%;在瑞香素浓度为0.1、1、100和1000μmol/L,作用6h后,RNR活性分别被抑制3%、31%、58%和93%;而瑞香素-Fe复合物作用6h后RNR活性分别被抑制8%、6%、11%和9%。

The effect of daphnetin and daphnetin-Fe complex on COX and RNR activity of P.falciparum was tested by ultraviolet spectrophotometer and electron spin resonance respectively.

结果 体外同步培养的恶性疟原虫经瑞香素(100μmol/L)作用2、4、8和12h后,COX活性分别被抑制了0、6%、73%和80%;在瑞香素浓度为0.1、1、100和1000μmol/L,作用6h后,COX活性分别被抑制3%、31%、53%和84%;而瑞香素-Fe复合物对COX的影响几乎消失。

The effect of different factors was investigated and the main process conditions were obtained: addition temperature120~140℃,esterify temperature:160~175℃,n:n=3~4:1mol:mol),n(DCPD:n =0.6~0.8:1mol:mol),the amount of catalyst is

双环戊二烯的含量低于80%,研究了各种影响因素,得出主要工艺条件:加成温度为120~140℃,酯化温度为160~175℃,n:n=3~4:1,n:n=0.6~0.8:1,催化剂用量为0.1~0.2%,树脂收率达

Ea for the concerted mechanism was 167.24 kJ/mol, while it was 155.20 kJ/mol for the formation of ethoxide intermediate in the stepwise mechanism.

比较苯与乙醇和乙烯发生烷基化反应的机理可以看出,二者作为烷基化试剂对烷基化反应性能影响不大。

METHODS: The third passage of BMSCs and AMSCs at a density of 5×10^7 L^(-1) were divided into two groups. Cells in the induction group were incubated in 1.5 mL of osteoinductive medium, supplemented with 10^8 mol/L dexamethasone, 10 mol/L β-glycerophosphoric acid, and 50 mg/L vitamin C. Cells in the non-induction group were not treated with osteoinductive medium.

选取第3代骨髓间充质干细胞和脂肪间充质干细胞,按5×10^7L^(-1)接种后各分为2组:诱导组加入含10^8mol/L地塞米松、10mol/L β-甘油磷酸、50mg/L维生素C的成骨诱导培养基1.5mL,未诱导组不加入成骨诱导培养基。

Then two star-shaped oligomers with designed molecular weights 5000 g mol-1 and 10000 g mol-1, respectively, were synthesized from D, L-lactide and glycolide as raw materials and pentaerythritol as initiator under catalysis of dibutyltin oxide.

以合成的丙交酯和乙交酯为原料,季戊四醇为引发剂,氧化二丁基锡为催化剂合成出设计分子量为5000和10000两种预聚物。

The results of absorption spectra, KI fluorescence quenching studies, competitive binding studies and thermal denaturation experiments suggested that the interaction between AQS and DNA be intercalative.

在CT DNA存在下,KI对AQS光化学反应产物的荧光猝灭常数K〓比没有CT DNA存在情况下的要小。2.5×10〓mol/L的溴化乙锭即可将3.2×10〓mol/L的AQS从AQS与DNA的结合物中完全置换出来。

The data of element analysis,melting point,IR and NMR for the product are consistent with the standard data,the purity exceeds 98%.3-methyl-2-oxobutanoic acid sodium ; sodium methoxide ; isobutyraldehyde ; diethyl oxalate

WSR-1熔点仪;Vario EL元素分析仪(德国E le-mentar公司);Nexus 870型傅立叶变换红外光谱仪;aV500核磁共振仪。1.2 3-甲基-2-氧代丁酸钠的制备将15.4 g(0.28 mol)甲醇钠与60 mL(1.5 mol)甲醇装入500 m

Result 1 Magnetic nanoparticles, magnetic nanoparticles modified with antisense oligodeoxynucleotide of human telomerase reverse transcriptase induced HL-60 tumor cells to apoptosis, we could see typical morphologic change of apoptosis cells: karyopyknosis, chromation"s condensing and aggregation in nuclear, forming crescent-shaped or annulus structures to lean on edge of cell nucleus"s membrane and posing apoptosis body by Atomic Force Microscope, Fluorescence microscope, transmission electron Microscope 2 There was a significant difference compared with control group(p.01), inhibition ratio had significant positive correlation with medication dosage and time ;during 0.8-8μM dosage amplitude, inhibition ratio accrescenced by dosages increasing. However, the inhibition ratio would decrease when dosage over 8-80μM.

结果 1 磁性纳米粒子、修饰有端粒酶反义寡核苷酸的磁性纳米粒子诱导HL-60细胞发生凋亡,原子力显微镜、光学显微镜、荧光显微镜和透射电镜下均观察到HL-60细胞呈现典型的凋亡细胞的形态变化:细胞核固缩,核内染色质浓缩、凝聚、形成新月形或环状结构紧靠在细胞核膜边缘,并形成凋亡小体。2 磁性纳米粒子、修饰有端粒酶反义寡聚脱氧核苷酸的磁性纳米粒子对HL-60肿瘤细胞的生长和增殖有明显的抑制作用,与对照组相比有显著性差异(p<0.01),在剂量为0.8-8μmol/L范围内,抑制率随剂量的增加而增加,当剂量超过8μmol/L时,抑制率反而下降;3 磁性纳米粒子、修饰有端粒酶反义寡聚脱氧核苷酸的磁性纳米粒子可增强p53基因的表达活性,引起DNA降解损伤,反向调节细胞周期活动,促使细胞从G0期进入G1期,抑制肿瘤细胞的生长。4 修饰有端粒酶反义寡聚脱氧核苷酸的量子点能通过内吞作用进入HL-60肿瘤细胞的细胞核,可以在细胞内进行定位和促进HL-60肿瘤细胞的凋亡。

Results Semen leucocytic density and nitric oxide l...

结果 白细胞精子症不育组白细胞的密度为(1.4 8± 0 。90 )× 10 9/L ,NO水平为(10 3.5± 2 。0 )μmol/L ,显著高于正常生育组的(0 。73± 0 。2 8)× 10 9/L和(41.6± 1.8)μmol/L (P分别为。0 5和。0 0 1)。

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What would he tell Judith and the children?

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