查询词典 modulation

GABA-ergic neuron may involve in the modulation of acetylcholine releasing in spinal cord and in the thermoregulation in preoptic area and anterior hypothalamus,which may lead to the TPM related hypohidrosis.

4GABA能神经元可能参与节前胆碱能神经元调节、GABA能神经元参与丘脑下部对高温的反应。这种参与活动可能与TPM泌汗障碍相关。

Results are as followed:1 Exposure of HELF cells to BP caused c-Jun activation,and increased the activity of MAPK,PI-3K,p53 and cyclin D1 pathway.2 BP-induced c-Jun activation was inhibited by dominant negative mutants of extracellular signal-regulated protein kinase or c-Jun NH_2-terminal kinase,but not by p38,impling that JNK and ERK pathways medicate c-Jun activation induced by BP.3 Overexpression of dominant-negative mutants PI-3K and Akt potently blocked phosphorylations of c-Jun and ERK,but not JNK in response to BP,suggesting that PI-3K/Akt pathway positively regulates BP-induced c-Jun activation through ERK.4 Inhibition of p53 by its chemical or molecular inhibitor markedly increased the phosphorylation levels of c-Jun,Akt and ERK upon BP stimulation,indicating that p53 negatively medicates BP-induced c-Jun activation through PI-3K/Akt/ERK pathway.5 The cell lines expressed TAM67 exhibits no significant affecting normal cell growth properties.6 TAM67 was able to significantly block G_1-S transition and subsequent cell proliferation,suggesting that c-Jun is essential for cell cycle alternations elicited by BP.7 Overexpression of TAM67 impaired BP-induced cyclin D1 activation,decreasing expression of E2F1 and pRb,indicating that c-Jun participates in the modulation of BP-induced activation of cyclin D1/pRb/E2F1 pathway.8 Stably expression of TAM67 led to the increases in the expression levels of p53 and p21,elevating phosphorylation level of p53,clearly indicating that c-Jun regulates p53/p21 pathway activation induced by BRCollectively,PI3K/Akt/ERK pathway mediated BP-induced c-Jun activation through p53-dependent mechanism.

结果显示：1BP刺激细胞可促进c-Jun活化，并伴随着MAPK、PI-3K、p53和cyclinD1通路各组成成分的活性增强。2利用MAPK通路的显性失活突变体分别阻断细胞外信号调节激酶和c-Jun氨基末端激酶活性，均可明显抑制BP诱导的c-Jun活化，但阻断p38活性对BP引起的c-Jun活化无明显影响，提示JNK和ERK通路参与调控BP诱导的c-Jun活化。3过表达PI-3K和Akt的显性失活突变体也可显著抑制BP诱导的c-Jun活化，并降低磷酸化ERK的表达水平，但对磷酸化JNK的表达水平无明显影响，说明PI-3K/Akt通路通过ERK正性调控了BP诱导的c-Jun活化。4p53的化学/分子抑制剂能使BP作用的细胞内c-Jun活性明显增加，并同时诱导Akt和ERK的磷酸化水平的升高，表明p53可通过PI-3K/Akt/ERK通路对BP诱导的c-Jun活化进行负性调控。5随后观察转染细胞的生长情况，发现TAM67对细胞正常生长和形态无明显影响。6稳定表达TAM67可有效抑制BP诱导的S期细胞数的增加，提示c-Jun在BP致细胞周期改变的过程中发挥了重要作用。7TAM67过表达能够抑制BP诱导的cyclin D1活化，降低磷酸化Rb以及E2F1蛋白表达水平，表明c-Jun参与调控BP诱导的cyclin D1/Rb/E2F1通路的活化。8过表达TAM67可使BP刺激的细胞中p53、p21总蛋白以及p53磷酸化的表达水平明显升高，可见c-Jun也参与调控BP诱导的p53/p21通路活化。

In the application of the OFDM system, combined with the adaptive modulation, adaptive coding and the receive diversity based on the accurate estimation of the characteristic of the subchannels, we can increase the spectrum usage, reduce the transmission power, the intercarrier interference and the peak-to-average power rate. So the system performance is optimized.

在OFDM系统的应用中，在对各子信道特性的准确快速估计的基础上，通过对各子载波进行自适应调制，自适应信道编码，以及和接收端的分集接收相结合，能够提高频谱利用率，降低发射功率，抑制子载波间干扰和降低功率峰均比，从而能够使系统的性能达到最优。

Single-phase Sinusoidal Pulse Width Modulation Inverter Power Supply in this paper belongs to AC power supply (AC-DC-AC convert). Control mode adopts feedback of voltage control. The methods of intermitting power flux and changing duty-cycle can change pulse width of drive voltage that adjust and rectify output voltage ultimately.

本文设计的单相脉宽调制逆变电源属于交流电源，采用电压反馈控制，通过中断功率通量和调节占空比的方法来改变驱动电压脉冲宽度来调整和稳定输出电压。

Of them 25 cases of oral cancer (G1-2) were randomly divided into trail and control group . The remained 11 cases of nasopharyngeal and maxillary sinus cancer (NPC-MSC, mainly G3-4) were attributed to a third group (1st course: sBRM, then 2nd course: IAC). The order of drug-use of sBRM is: pre-immunomodulation of the reactivity of patient low-dose CTX and PolyI∶C, then in- juring tumor and thereby modulation of its immunogeneity (DDP-PYM regimen , thereafter, reaction enhancement modu- lation [low-dose rhuIL-2, Cimetidine and Indomethacin ] . All drugs, except for CTX, PolyI∶C and Indo, were fractionally delivered in a manner of continously infution in 8-10 hours via a retaining intra-external carotid artery catheter CAVAFIX 335 SPLITTOCAN G14, B.

将其中25例晚期口腔高、中分化鳞癌病人随机分为实验治疗（12例）和对照治疗（13例）两组，实验组采用sBRM疗法，具体用药为：先用小剂量环磷酰胺和聚肌胞对机体反应性作预调变，然后用低剂量DDP-PYM化疗杀伤&致创&癌细胞，使其免疫原性增强并借之诱导肿瘤浸润淋巴细胞，化疗结束后续用小剂量rhuIL-2激活和扩增TIL，特别是其中的T细胞，并借助小剂量西咪替丁、消炎痛调节机体以原发灶为中心的癌受创相关反应。

Adolescents have a lower, general evaluation on Internet environment and they are not satisfied with it;Adolescents have positive behaviors rather than negative behaviors on Internet; Adolescents have a higher self-evaluation on Internet;The commonly and frequently negative Internet be}viors are cheating, legpulling and adventuring, etc; The Internet use motivations are Chat on-line, amusement reception, correspondance, emotional modulation,etc. negative influence on a few numbers of the adolescents;, Internet use information only has a

1青少年对互联网环境的总体评价较低；在互联网中积极的行为多于消极的行为；对自我互联网行为的评价高于对他人的行为评价；常见的消极互联网行为依次是欺骗、恶作剧与冒险，且对他人构成的消极影响较小；互联网使用动机依次是在线聊天、娱乐休闲、获得信息、与亲朋好友联系和调节情绪；互联网使用只对少数青少年个体造成负面影响

Analyze the gain spectrum of modulation instability under specific nonlinear responds. We take logarithmically nonlinear medium as an example to discuss MI gain spectrum of coherent and incoherent beams both.

一、我们在微扰近似下，分析了介质的非线性响应形式对调制非稳增益的影响，以对数型非线性介质为例分别讨论了相干光束和非相干光束的调制非稳性。

Objective To observe the modulation by Blood-cooling and Blood Flow-promoting Herbs to expressions of tumor necrosis factor u and basic fibroblast growth factors in radiation-induced lung injury of rats at different radiation times, and explore the mechanism of prevention and curative effect of the herbs on radsation lurg injury.

目的 通过观察凉血活血中药对剂量分割重复照射下大鼠肺组织肿瘤坏死因子-α、碱性成纤维生长因子在不同时相动态表达的影响，探讨其防治放射性肺损伤的作用机制。

First, the relation between the phase modulation and the LUT value was measured with the linear LUT curve.

研究了液晶波前校正器位相调制曲线非线性的校正以及液晶自适应闭环对畸变波前的校正。

Objective:To explore the action of immuno-modulation of lycium barbarum polysaccharides on mouse splenocyte and it ' s possible mechanism in vitro.

摘 要 目的：探讨枸杞多糖对免疫细胞功能的直接作用及其机理。

For a big chunk of credit-card losses; the number of filings (and thus charge-off rates) would be rising again, whether

年美国个人破产法的一个改动使得破产登记急速下降，而后引起了信用卡大规模的亏损。

Eph. 4:23 And that you be renewed in the spirit of your mind

弗四23 而在你们心思的灵里得以更新