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The cerebral mitochondrial impairment model provides a new method to investigate the pathologies and medicines of AD.

NaN3造成的脑线粒体损伤模型为AD机理和治疗药物的研究提供了新的途径。

They are synthesized in the cytoplasm, then translocated to mitochondrial and located in the inner membrane by specific transport mechanism.

该家族成员由细胞质合成，经特定的转运机制，运输入线粒体，并定位于线粒体内膜，负责小分子物质跨线粒体内膜的转运。

In heathlty cells, AIF protein is normally confined to mitochondrial intermembrane space. However, after apoptosis is induced, AIF protein can be released from mitochondria and translocates into nucleus leading by its nuclear localization signal.

正常情况下，AIF蛋白定位于细胞线粒体膜间隙，当有凋亡信号刺激时，AIF分子从线粒体释放到细胞浆，再通过其核定位信号转位到细胞核中，直接引起染色体凝集和DNA的大片段(~50kb)断裂，导致细胞凋亡。

Endo G is a mitochondrial DNA enzyme which translocates to nucleus after releasing from mitochondrion and cuts chromatin DNA into nucleosome fragments in a caspase-independent manner.

Endo G是一种线粒体DNA酶，当其从线粒体释放出来之后，可以转位到细胞核，并且以caspase非依赖性方式将染色质DNA剪切为核小体碎片。

In order to establish the simple extraction method of wheat mitochondrial DNA, this study investigated the effects of triturating material, exacting mitochondria and exacting and purifying mtDNA from yellow seedling of wheat, respectively.

为了建立小麦线粒体DNA快速提取体系，以小麦黄化苗为材料，分别研究了材料的研磨、线粗体的抽提和mtDNA的提取及纯化过程中众因素的影响。

It uncouples oxidative phosphorylation but, unlike the aflatoxins, does not induce mitochondrial swelling or hinder Ca2+-induced swelling of mitochondria.

它解开氧化磷酸化但不像黄曲霉毒素类，不能诱导线粒体肿胀或阻止Ca2+诱导的线粒体肿胀。

The recent researches show that effect of 'mild uncoupling' of respiratory chain is involved in mitochondrial anti-oxidation event.

目前的研究表明，线粒体呼吸链&温和解偶联&机制也参与了线粒体内的抗氧化防御过程。

The observed effects appear to result from mitochondrial uncoupling, uptake of the drugs, biliary secretion of their metabolites, and from inhibition of potassium channels.

这些观察到的变化是由于线粒体的脱耦联、药物的吸收、代谢产物的胆道分泌及对钾离子通道的抑制造成的。

The injured gill cells had a different ultrastructure, with endoplasmic reticulum dilated and vesiculated, mitochondrial cristaes partially disintegrated, gill fibre cuticles denatured and dropped. The ultrastructural damages to hepatopancreatic cells were characterized by the decrease of microvilli, swelling and breaking up of mitochondria, expansion of endoplasmic reticulum, disruption and vacuolization of nucleus, tumefaction of nuclear membrane and increase of lipid droplets. As for the toxicological changes of myocardial cells, the mitochondria were swelling, having a lot of vacuolus and disintegrating, while the myofibrils were irregular with endoplasmic reticulum dissolved.

鳃细胞的损害表现为鳃丝水肿，细胞器溶解，角质层变薄，线粒体、内质网的肿胀、解体；肝胰脏细胞的主要损害特征为肝管微绒毛减少，线粒体水肿解体，内质网扩张，细胞核空泡化，核膜水肿和脂肪滴增加；心脏细胞的毒理变化为线粒体内嵴肿胀、瓦解，肌原纤维不规则，内质网溶解。

Control group was also set up.Then the AO/EB fluorescence double-dye technique,immunocytochemistry staining,Fluo-3 staining and Rhodamine 123 uptake assay approaches were adopted to observe the apoptotic rate,expression levels of Bcl-2 and Bax proteins,concentration of cytoplasmic free Ca2+ and mitochondrial transmembrane potential of NCI-H460 cells.

采用AO/EB荧光双染、免疫细胞化学染色、Rhodamine 123摄取法及Fluo-3/AM染色分别观察NCI-H460细胞的凋亡、Bcl-2及Bax蛋白的表达量、线粒体跨膜电位及细胞内游离钙离子浓度。

The concept of equivalent rotationally rigidity is offered and the formula of rotationally rigidity is obtained.

主要做了如下几个方面的工作：对伸臂位于顶部的单层框架—筒体模型进行分析，提出了等效转动约束的概念和转动约束刚度的表达式。

Male cats normally do not need aftercare with the exception of the night after the anesthetic.

男猫通常不需要善后除了晚上的麻醉。