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A single point mutation in intervening sequence 2 (IVS2) of human mitochondrial arginyl-tRNA synthetase gene causes abnormal cleavage of its transcript, resulting in pontocerebellar hypoplasia.

人线粒体精氨酰-tRNA合成酶基因2号内含子中的一个单点突变导致该基因的转录本被异常剪接，造成脑桥小脑发育不全。

Mitochondrial 16S rRNA gene and COⅠ gene fragments were amplified and sequenced from 4 wild populations of Portunus trituberculatus. Respectively, 524bp and 658bp long partial gene fragments of the 16S rRNA gene and the COⅠ gene were obtained. A high percentage of A+T base composition in the two sequences was observed, which was similar to the results of studies on drosophila, shrimp, crab and other invertebrates.

对分别采自辽东湾、莱州湾、海州湾和舟山的三疣梭子蟹4个野生群体的线粒体16S rRNA和COⅠ基因片段进行了扩增和测序，分别得到长度为524bp和658bp的片段。2段序列的碱基组成均显示较高的A+T比例（16S rRNA基因70.8%，COⅠ基因63%），这与果蝇、虾类、蟹类等无脊椎动物的16S rRNA和COⅠ基因片段研究结果相似。

The prolyl hydroxylase inhibitor DMOG inhibited apoptosis and cell death induced by serum deprivation in MSCs concurrent with HIF-1αstabilization, mitochondrial protection,and activation of the PI3K/Akt pathway.

实验结论：1、DMOG能够降低MSCs内HIF-1α的降解和上调下游Glut-1的表达，在作用浓度下对MSCs没有明显的毒性作用；2、DMOG能够降低缺血清状况下MSCs的凋亡和死亡；3、caspase-3依赖的和非依赖的线粒体通路可能在DMOG对MSCs保护中发挥了一定的作用；4、PI3K/Akt通路在DMOG对MSCs的保护中发挥了重要的作用。

MSG could insult the functions and structures of specific brain areas of adult mice through blood-brain barrier. The ability of discrimination learning in Y-maze was affected markedly, especially in 4. 0g/kg MSG group, meanwhile, dark pyknotic and loss of neurons were shown in arcuate nucleus of hypothalamus, but not in hippocampus. Consistent changes occured in mitochondrial membrane protein bound 〓 by 〓-fluoresent probe, i.

MSG可以透过成年小鼠血脑屏障产生神经毒性作用。4.0g/kg MSG对小鼠空间分辨学习能力的损伤程度较2.5g/kg MSG更为明显，同时下丘脑弓状核神经元出现核固缩及神经元数目明显减少，相同处理未引起海马神经元的明显变化。

Phylogenetic relationships of brown frogs with 24 chromosomes from Far East Russia and Hokkaido assessed by mitochondrial cytochrome b gene sequences ( Rana : Ranidae).

亲缘关系的布朗与24个染色体青蛙从俄罗斯远东地区和北海道进行评估，线粒体细胞色素b基因序列。

O-GlcNAc signaling represents a unique endogenously recruitable mechanism of cardioprotection that may involve direct modification of mitochondrial proteins critical for survival such as voltage-dependent anion channel.

O-链β-N-乙酰氨基葡萄糖信号代表一种独特的内源性的的心脏保护修复机制，其包括残存的线粒体蛋白直接修复，如电压依靠性阴离子通道

Previous study showed that over-expression of PICK1 in human leukemia REH cells rendered a higher resistance to etoposide-induced apoptosis through a recruitment of PKC alpha which resulted in maintenance of mitochondrial membrane potential, an enhanced phosphorylation of the anti-apoptotic Bcl-2 protein at Ser70, and inhibition of Bax dimerization.

在本实验室先前的研究，於人类血癌REH细胞中过度表现PICK1蛋白质，PICK1能够藉由招揽蛋白激酶C alpha至粒线体上，引起Bcl-2磷酸化程度提高，抑制Bax蛋白二聚体的形成，进而稳定粒线体的膜电位，以至於细胞对於化疗药物etoposide引起的程式凋亡具有抗药性。

The primary culture chondrocytes were round or polygonal shape, half of the 4th generation turned to spindle shape, most of the 6th passage were long spindle shape; The rough endoplasmic reticula and the mitochondrial were rich and well developed, the ability of proliferation of the 3th generation were stronger than the first one, while the 5th generation was weaker.

原代软骨细胞呈圆形或多角形，第4代有一半变成梭形，第5代绝大部分变为长梭形；原代软骨细胞胞浆内粗面内质网和线粒体丰富，第3代软骨细胞生长增殖能力强于原代，第5代增殖能力明显减弱。

In electron microscopy endothelial cell of capillary and mitochondrial was edematous obviously, the basement membranes were thickened. RGCs were vacuolated, chromatin of nucleus aggregated marginally decreased and densification. Some of RGCs were necrosis, nucleus were dissolved, mitochondria was edematous, the rough endoplasmic reticula decreased obviously.

电镜下视网膜毛细血管内皮细胞明显肿胀，胞体变圆，突向管腔，线粒体肿胀，空泡化，基底膜增厚，视网膜神经节细胞胞体变形，核明显固缩，核膜消失，胞浆空泡化，线粒体肿胀，细胞表面突起减少，多聚核糖体及粗面内质网显著减少。

The mechanisms by which rottlerin inhibited PDT with aloe-emodin-induced H460 cell anoikis probably involved the changes in mitochondrial functions, the expression of cytoskeleton regulatory proteins and the translocation of PKCα,δ and ε.

我们证实rottlerin对於芦荟大黄素配合光动力疗法引发H460细胞失巢凋亡的抑制应与粒线体功能、PKC家族成员的蛋白分布及细胞骨架调控蛋白的表现有关。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。