查询词典 mitochondria

PartⅢEffect of DM on release of cytochrome C in neurocyte mitochondria Objectivity: To study the effect of DM on release of cytochrome C in neurocyte mitochondria.

第三部分溴氰菊酯对神经细胞线粒体细胞色素C释放的影响目的：探讨溴氰菊酯对神经细胞线粒体细胞色素C释放的影响。

Western Blot indicated that AIF was selectively released before cytochrome C from the intermembrane space of mitochondria to cytosol, and that release needed Bax relocation to mitochondria. Results above suggest that caspase-independent cell death maybe occurred earlier than caspase-dependent cell death in staurosporine induced T lymphocytes apoptosis. Caspase-independent cell death is an alternative pathway of cell death which could guarantee the safe and noninflammatory removal of corpses when caspase was mutented or blocked in the cell, it plays an important role in maintaining the number of T lymphocytes and ensuring the proper function of immune system.

细胞caspase非依赖死亡方式可能是Caspase依赖性死亡方式的替代途径，它可以保证在Caspase发生突变或通路受阻时，T细胞仍然能够正常死亡，这对于维持T细胞的数量和保证免疫系统正常功能的发挥具有十分重要的意义。

Light microscope and transmission electron microscopy showed that SMMC-7721 cells induced by SAHA had undergone the restorational alteration in morphology and ultrastructure, which were different from those of nontreated cells but were similar to those of normal cells, and the changes were as follows: the cells turned to be flat and spread; the nucleo-cytoplasmic ratio lessened and nuclear shape became rather regular; the number of nucleolus reduced and its volume lessened; euchromatin increased while heterochromatin decreased in nucleus; in the cytoplasm, mitochondria grew in number with relatively consistent structure and well-developed mitochondria cristae; Golgi complex turned to be well-developed and typical; rough endoplasmic reticulum increased. Immunocytochemistry assay showed that the expression of AFP and PCNA were declined significantly. FCM analysis showed SAHA could arrest SMMC-7721 cells in G0/G1 phase, with an accumulation of the cells in G0/G1 phase while a decrease of cells in S phase. Semi-quantitative RT-PCR detection revealed that the expression of p21WAFl mRNA was upregulated remarkably in the cells treated with SAHA.

结果：倒置显微镜和透射电镜观察显示，经SAHA处理的细胞增殖速度显著减慢，细胞体积增大，细胞核较小，形状较为规则，核仁数量减少、体积变小，核内常染色质增多而异染色质减少，核质比例减小，细胞质内线粒体数量增多、线粒体嵴发达，高尔基体较为典型，粗糙型内质网增多，呈现出与正常上皮细胞相似的形态变化；MTT比色法测定结果显示不同浓度(2.5、5.0、7.5、10.0uM)SAHA对SMMC-7721细胞的增殖均有抑制作用，并有明显的剂量依赖和时间依赖关系；免疫细胞化学检测显示SAHA能显著降低PCNA和AFP在SMMC-7721细胞中的表达；流式细胞仪检测结果显示，SMMC-7721细胞经SAHA处理后，G0/G1期细胞明显增加，S期细胞则明显减少，细胞被阻滞于G0/G1期；RT-PCR检测结果表明，SAHA作用12h后SMMC-7721细胞中p21WAF1 mRNA的表达即有增加，24h后更为明显。

It was observed by means of electronic microscope that toxinresulted in the apparent change in ultrastructure of rapeseed leafincluding the damage of chloroplast membrane,dilated,disorderedgrana lamellae;the damage of mitochondria membrance andeventually vacuolated mitochondria;the contract of cell nuclein.

电镜观察发现：菌核菌产生的毒素引起油菜叶片超显微结构显著变化，主要包括叶绿体膜破坏，基质片层肿胀，排列紊乱，形成空腔，最终叶绿体解体；线粒体膜破坏，最后空泡化；细胞核质凝缩。

Analysis of mitochondrial DNA composition of the panda-rabit cloned embryos found that mitochondria from both panda somatic cells and rabbit ooplasm co-existed in early blastocyst, but mitochondria from rabbit ooplasm decreased and those from panda donor cells dominated in early fetuses after implantation.

结果显示，应用卵裂球电融合方法可以制作一系列的多倍体胚胎；小鼠囊胚的形成与胚胎中的细胞数目无直接关系，卵裂球的电融合和染色体数目的增加不会改变胚胎的发育进程；而胚胎细胞中的核／质比可能是控制胚胎囊胚化的一个重要因素。

The transmission electron microscope revealed endoplasmic reticula were dilated, the matrix of mitochondria became pale and the cristae of mitochondria shorter in stromal cells from irradiation mice compared with those of controls.

提示：放射复合伤骨髓基质细胞的细胞周期比例、DNA含量和形态的改变可能是导致放射复合伤造血微环境损伤的重要原因之一。

It is tentative investigated the transferring of mitochondria by microinjection. It is found that the key of the success of transferring of mitochondria by microinjection is not the microinjected from pollen grain trema, but the cultivated of the microinjected pollen grain.

对显微注射转移植物线粒体的技术进行了探索性研究，结果表明，该技术的难点不在通过花粉粒萌发孔进行mtDNA的显微注射，而在注射后花粉粒的培养。

In conclusion, plateau zokor and plateau pika adapt better to hypoxia than SD rat by increasing the SV of mitochondria, MVD and content of Mb in the cardiac muscle. However, the parameters of mitochondria in the two high-altitude animals are different possibly because of the differences of habitats and habits.

以上结果提示，高原鼢鼠和高原鼠兔通过增加心肌线粒体SV、MVD以及Mb含量提高其在低氧环境获取氧的能力；同时，由于生境和习性上的不同，两者线粒体指标又表现出差异性。

This study demonstrated that cytotoxicity of adrenoco rtical cells induced by lead acetate is probably attributed to mitochondria oxid ative stress. Mitochondria damage might be the early cellular and molecular even t in toxic effect of lead on adrenal cortex.

线粒体氧化应激介导肾上腺皮质细胞毒性可能是PbAc毒作用机制之一，线粒体损伤是铅致肾上腺皮质毒作用的早期细胞和分子事件。

Ultrastructural examination revealed swelling and disorganization of cristae in myocardial mitochondria in traumatic group, and only slight swelling of mitochondria was found in intervention group.

电镜观察显示，创伤组心肌线粒体肿胀、嵴断裂，可见较大的线粒体，而干预组线粒体仅轻度肿胀。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。