查询词典 mismatch

For maintain the genome integrity and fidelity. DNA repair processes are classified into pathways responsible for repairing specific classes of DNA damage, although recent data indicated that some proteins function in multiple pathways. Base excision repair occurs through excision of a damaged region, followed by fill-in repair synthesis using the opposite strand as a template. Mismatch repair operates on base mismatched and small loop-outs that arising during replication by misincorporation or slippage on the template strand. Nucleotide excision repair removes photoproducts from u.v. radiaton and bulky adducts from a multiple of chemicals. DNA double-strand breaks may be rectified by either homologous recombination repair and nonhomologous end joining pathways where both strands of the DNA duplex are damaged.

DNA修补基因可藉由不同的机制对不同程度的DNA损害进行修复，虽然近来已有文献指出，一些DNA修复蛋白可能参与多种DNA修复机制，不过一般可分为下列四种DNA修复机制：碱基删除修复(Base Excision Repair； BER)，即对较小的DNA损伤，进行修复；核苷酸错误配对删除修复，即对复制时所产生的核苷酸配对错误或模板滑动造成的DNA损害进行修复；核苷酸删除修复(Nucleotide Excision Repair； NER)，即对因紫外线或有机化合物所造成的较大损伤进行修复；以及双股DNA断裂修复(Double-Strand Breaks； DSBs)，即对双股DNA断裂进行修复，此机制又可分为同源染色体的重组与末端接合两种主要路径，对受损的DNA进行修复。

I didn't watch TV last night, because it .

昨晚我没有看电视，因为电视机坏了。

Since this year, in a lot of villages of Beijing, TV of elevator liquid crystal was removed.

今年以来，在北京的很多小区里，电梯液晶电视被撤了下来。