查询词典 microsomal

On the other hand, the hepatic microsomal aminopyrine demethylase activity was obviously inhibited 2 hours after administration of the same dose of SY-801 and SY-640, while the content of hepatic cytochrome P-450 was not affected.

体外实验表明，SY-801和SY-640对正常小鼠、3-甲基胆蒽（3-MC）处理小鼠及苯巴比妥处理小鼠小鼠肝微粒体氨基比林脱甲基酶活性都具有明显的抑制作用，其中对3-MC处理小鼠肝微粒体氨基比林脱甲基酶活性抑制作用最显著。

In order to study the relation of cytochrome P-450 with the protective action of SY-801 and SY-640 against 〓-induced UDS and 3H-BP binding to nuclear DNA, the effects of SY-801 and SY-640 on liver microsomal cytochrome P-450 were studied in mice. The results indicated that the liver microsomal cytochrome P-450 concentration and aminopyrine demethylase activity were significantly increased in mice pretreated with SY-801 150mg/kg or SY-640 150 mg/kg once daily for three days.

本实验进而观察了SY-801对小鼠肝微粒体细胞色素P-450酶系的影响，结果表明SY-801和SY-640体内连续给药3天，可诱导小鼠肝微粒体细胞色素P-450含量明显增加，同时氨基比林脱甲基酶活性亦明显增加；给药1次2小时内二者均可抑制氨基比林脱甲基酶活性，而对肝微粒体细胞色素P-450含量则无明显影响。

Methods The activities of liver microsomal erythromycin N-demethylaseand aminopyrine N-demethylase were measured by spectrophotometry. The levels of mRNA expressions of CYP3A1, CYP1A2, CYP2E1, mdrla and mdrlb in hepatic microsome were determined with RT-PCR method.

用分光光度法测定大鼠肝微粒体红霉素N-脱甲基酶、氨基比林N-脱甲基酶的活性，用逆转录聚合酶链反应技术测定大鼠肝脏CYP3A1、CYP1A2、CYP2E1、mdr la和mdr lb基因的水平。

Mehtod: animals were given intraperitoneally normal saline(10ml/kg.d), phenobarbital (40mg/kg.d) and puerarin (100, 200mg/kg.d) respectively for seven days. Then the levels of hepatic microsomal CYP and cytochrome b5(Cytb5), and the activities of aniline hydroxylase and aminopyrine N-demethylase were determined by spectrophotography.

实验动物分别腹腔注射生理盐水、苯巴比妥（40mg/kg.d）、葛根素（100和200 mg/kg.d），给药7d后，用分光光度法测定肝微粒体CYP和细胞色素b5(Cytb5)的含量，以及苯胺羟化酶和氨基比林N-脱甲基酶的活性。

Mehtod: The animals were given intraperitoneally normal saline(10ml/kg.d), phenobarbital (40mg/kg.d) and puerarin (100, 200mg/kg.d) respectively for seven days. Then the levels of hepatic microsomal CYP and cytochrome b5(Cytb5), and the activities of aniline hydroxylase and aminopyrine N-demethylase were determined by spectrophotography.

实验动物分别腹腔注射生理盐水、苯巴比妥（40mg/kg.d）、葛根素（100和200 mg/kg.d），给药7d后，用分光光度法测定肝微粒体CYP和细胞色素b5(Cytb5)的含量，以及苯胺羟化酶和氨基比林N-脱甲基酶的活性。

Mitochondrial fatty acid oxidation is decreased, and peroxisomal and microsomal oxidation is complementally upregulated to decrease fatty acid accumulation.

线粒体脂肪酸氧化作用减少，过氧化物和微粒体氧化作用代偿性上调以减少脂肪酸的累积。

Heme oxygenaseis one of the important component of microsomal enzyme system,which can catalyze degradation of haemoglobin into bilirubin,ferri ion,and carbon monoxide.

血红素加氧酶是组成微粒体酶系统的重要组分之一，它能催化降解血红素生成胆红素、游离铁离子和一氧化碳。

An example of a flavoprotein undergoing a one-electron transfer is with the microsomal NADPH-cytochrome P450 reductase.

的一个经历一个单电子转移黄素蛋白的例子是与微粒NADPH -细胞色素P450还原酶。

They act as electron-transport agents and play an important role in the electron-transport chains of respiration, photosynthesis, and the microsomal system responsible for the desaturation of fatty acids in heterotroph ic bacteria.

它们作为电子传递物在呼吸电子迁移链、光合作用及微粒体系统中起重要作用，它还负责异养细菌中脂肪酸的去饱和作用。你知道它的英文吗？

At concentration of 2% PEG8000, 30% microsomal protein containing 10% of total P450 was precipitated. At concentration of 5% PEG8000, 55% microsomal protein containing 20% of total P450 was precipitated. At concentration of 8% PEG8000, 78% microsomal protein containing 30% of total P450 was precipitated. At concentration of 11% PEG8000, 85% microsomal protein containing 70% of total P450 was precipitated.

当PEG的浓度为2％时，约30％的微粒体蛋白和10％的P450被沉淀；PEG为5％时，约55％的微粒体蛋白和20％的P450被沉淀；PEG为8％时，约78％的微粒体蛋白和30％的P450被沉淀；PEG为11％时，约85％的微粒体蛋白和70％的P450被沉淀。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。