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The HL60 cells were inoculatedsubcutaneously to nude mice and after the dimeter of tumorreached 5mm,the NIH3T3-IFN-〓 cells were implanted i.p.intothe tumor-bearing mice or DOX was injected i.p.into the tumor-bearing mice.

将HL60细胞皮下接种BALB/C裸鼠体内，至皮下肿瘤长至直径达5mm时，给荷瘤小鼠腹腔内埋植〓细胞或腹腔注射阿霉素，结果发现其皮下肿瘤生长被显著抑制，特别是当NIH 3T3-IFN-〓细胞与阿霉素联合应用时，肿瘤生长抑制作用最明显。

The effect of Jiusuyu on ebriety rate, ebriety time of acute alcoholism mice observed after preventing treatment 80 healthy mice, bisexual and each half, were randomly divided into 4 groups, 20 mice every group, namely model group (equal volume physiological saline were given through the means of watering stomach), low-dose group of Jiusuyu (called low-dose group, 1.62g/100g avoirdupois Jiusuyu drank through the means of watering stomach), high-dose group of Jiusuyu (called high-dose group, 3.24g/100g avoirdupois Jiusuyu drank through the means of watering stomach), and Gehuaji-echeng liquid control group (called control group, 1.31g/100g avoirdupois) Gehuajiecheng liquid were drunk through the mea

酒速愈预防性给药对急性酒精中毒小鼠醉酒时间、醉酒率的影响健康昆明种小鼠，雌雄各半，随机分为4组：模型组、酒速愈低剂量组(灌服酒速愈1.62g生药/100g体重)、酒速愈高剂量组(灌服酒速愈3.24g生药/100g体重)、葛花解酲汤组(灌服葛花解酲汤1.31g生药/100g体重)，每组20只。各组小鼠禁食12hs，各治疗组均一次性给药，模型组灌服生理盐水，30mins后均以56°红星二锅头酒灌胃(1.4ml/100g体重)。观察记录小鼠醉酒时间(从清醒到翻正反射消失的时间)，小鼠醉酒与否以翻正反射是否消失为标准：小鼠灌酒后将其背向下轻轻放入鼠笼，若小鼠背

Another 72 mice were randomly divided into control group,egg yolk model group,Expellant and Cleanning Fat Capsule 0.4 g·kg-1 group,CFB 10.0,5.0,2.5 mL·kg-1 groups (n=12).Mice in each group were exhibited once a day for 10 d.16 h before the last administration,except control group,the mice in other groups were injected with 75% yolk physiological salt solution 0.5mL through the abdominal cavity,and began to starve,1 h after the last administration, the contents of serum TCHO and TG were determined,and liver MDA level was measured.

另取小鼠72只随机分为空白对照组、蛋黄模型组、排毒清脂胶囊0.4 g·kg-1组及CFB 10.0、5.0和2.5 mL·kg-13个剂量组( n=12)，每天给药1次，连续 10 d，末次给药前16 h 除空白对照组外，所有各组小鼠每只均腹腔注射75％蛋黄生理盐水溶液0.5 mL，并且开始饥饿；末次给药后1 h测定血清TCHO及TG含量，取肝脏测MDA含量。

Methods anti-tumor activity of Phellinus linteus was estimated by the longevity of EAC mice,the immune effect of tumorous mice was tested by the experiment of carbon particle expurgation and the IL-2 concentration in serum of tumorous mice was determined by ELISA.

以小鼠艾氏腹水癌的生命延长率评价桑黄的抗肿瘤作用，以炭末廓清实验观察荷瘤小鼠非特异性免疫功能，以ELISA法测定荷瘤小鼠血清IL-2浓度。

Methods The anti-tumor activity of Phellinus linteus was estimated by the longevity of EAC mice,the immune effect of tumorous mice was tested by the experiment of carbon particle expurgation and the IL-2 concentration in serum of tumorous mice was determined by ELISA.

目的 观察桑黄对肿瘤的抑制作用及对机体免疫功能的影响方法以小鼠艾氏腹水癌的生命延长率评价桑黄的抗肿瘤作用，以炭末廓清实验观察荷瘤小鼠非特异性免疫功能，以ELISA法测定荷瘤小鼠血清IL-2浓度。

Methods The anti-tumor activity ofPhellinus linteus was estimated by the longevity of EAC mice,theimmune effect of tumorous mice was tested by the experiment ofcarbon particle expurgation and the IL-2 concentration in serum oftumorous mice was determined by ELISA.

以小鼠艾氏腹水癌的生命延长率评价桑黄的抗肿瘤作用，以炭末廓清实验观察荷瘤小鼠非特异性免疫功能，以ELISA法测定荷瘤小鼠血清IL-2浓度。

Methods: The lead-poisoned mice were prepared by drinking water containing lead acetate, and the administration of Yinling Ⅰ or EDTANa2Ca to lead-poisoned mice was performed for 3 weeks. The number of white blood cell, the rate of carbon expurgation, the index of immune organ of mice were detected to evaluate the non-special immune function.

小鼠自由饮用醋酸铅溶液造模，分别予银苓Ⅰ号或依地酸钠钙治疗3周；观察外周血弊细胞计数、碳粒廓清指数K及校正指数α、免疫脏器指数等非特异性免疫功能指标的变化。

Two kinds of tumor models, C57BL/6 mice bearing B16 melanoma and BALB/c mice bearing S180 fibrosarcoma were successfully established in the left leg of mice by subdermal injection of tumor cells.

在B16肿瘤模型中，小鼠左后肢皮下接种2×10〓/鼠B16细胞，于接种后第2、15、25天肿瘤局部注射NDV2×10〓PFU，同时设荷瘤对照组。

Because snails were eliminated when we poisoned fish in brooks and mice in houses or fields(mice are the final or transfer hosts of Paragonimus ) and mammals such as cats and dogs died by eating poison or poisoned fish or mice, the infection rate of P.

卫生并殖吸虫疫区感染率下降主要与溪河毒鱼时殃及螺蟹，房屋与田野毒鼠（并殖吸虫终末宿主或转续宿主）及致猫犬科动物误食毒鼠药饵或中毒的鱼、鼠致死所致。

Can accelerate the bone marrow cell from G1 phase into S phase when we measure it's Cell cycle, it make S phase rate was increased .thus it promoted DNA synthesize and repaired. Mice irradiated at dose of 5.5 Gy gamma-irradiation showed timed-related decreases and restores in peripheral blood picture at day 1 through day 21, the counts of WBC of these group had taken drug has various degree to increase than irradiation control group in day 1. Grugs failed to protected the peripheral blood cell at lowest point, but seems promote their rescovery.9803 treated group was distinct. At 7days after mice were radiated in 3.5 Gy. we observed drug can Significantly hold back the decreased number of hematopoietic progenitors colony forming radiation induced. These findings indicated 9803 have a certain radioprotective activity against gammer irradiation in mice.

给药组的 CFU-S 数量较照射对照组明显增加，3.5Gy 照后第七天观察给药9803组对小鼠骨髓造血组细胞集落生成能力的影响，给药组的造血祖细胞集落的形成能力强于照射对照组，并且9803组明显优于523组。5.5Gy 照射引起的小鼠的外周血细胞数量的降低以 WBC 发生最早，照后24小时给药组的 WBC 数量均比照射对照组有不同程度的升高，以9803各给药组最为明显，药物未能使照射引起的外周血细胞最低值升高，而有降低的趋势，但给药对照射后期外周血象的总体恢复有较好的促进作用。7.5Gy 照射后第七天测定小鼠骨髓细胞周期的测定中发现9803具有促进骨髓细胞由 G1期进入 S 期的效应，致使 G0/G1期细胞显著减少， S 期细胞比率显著增加，这利于促进 DNA 合成修复，即促进骨髓细胞增殖，骨髓细胞 DNA 含量给药组显著高于照射对照组。

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