查询词典 mice

objective to compare the anti-aging effects of lycium barbarum polysaccharides and tanshinone on the skin of d-galactose-induced mice aging model.methods 60 female mice were randomly divided into 4 groups (n=15):mice in normal control group received subcutaneous injection of normal saline and mice in the other 3 groups received cervicodorsal injection of d-galactose［1000 mg/(kg1·d)］ for 42 d to establish subacute aging model.the experimental groups included agingmodel group,lycium barbarum polysaccharides ［200 mg／group,tanshinone ［1 500 mg／］ group.forty two days later,the dorsal skin samples were collected to determine sod activities、mda and hydroxyproline contents.

60只雌性昆明种小鼠，随机分为4组(n=15)：正常对照组皮下注射生理盐水；其余3组每日颈背部皮下注射 d-半乳糖［1000 mg/］造成小鼠衰老模型，同时各组分别灌胃生理盐水、枸杞多糖［200 mg/］、丹参酮［1 500 mg/］。42 d后，测定小鼠背部皮肤组织匀浆中超氧化物歧化酶活力、过氧化脂质代谢产物丙二醛含量和皮肤羟脯氨酸含量。

Methods The mice were treated by ig FBD with the doses of 35, 70 and 140mg/kg for one week continuously. Effect of FBD on dysmnesia of acquired learning of mice induced by scopolamine, dysmnesia of memory retention of mice induced by NaNO2, and dysmnesia of reappearance of memory of mice induced by 45% ethanol were studied.

小鼠ig给予35、70、140mg/kg FBD，连续1周，观察FBD对东莨、莨菪碱所致小鼠记忆获得障碍、亚硝酸钠所致小鼠记忆巩固不良和45%乙醇致小鼠记忆再现障碍的影响，并观察FBD对大鼠双侧颈总动脉结扎所致的慢性脑部供血不足而产生的记忆障碍的改善作用。

Under inhibit tumor fall increment andalert confession The objective of this experiment is to prove the antitumor effect and its mechanism in vivo of Erysimum cheiranthoides. In this study we observe the ratio of inhibitory of mice bearing S180 and the effect of prolonging lives of mice bearing H22;the effect on immune function of mice bearing S180;the phagocytosis of MO cells; measuring serum TNF of mice bearing S180 with ELISA; the expression level of p53 in tumor tissue with ICH and the change of tumor cells shape with pathology test.

实验采用S_(180)、H_(22)两种瘤株，以昆明利，小鼠为研究对象，对体内的抑瘤作用、生命延长作用进行研究；对S_(180)荷瘤小鼠免疫功能影响的研究；采用碳粒廓清法研究该药对巨噬细胞吞噬功能影响的研究；采用ELISA法检测S_(180)荷瘤小鼠外周血TNF含量；采用免疫组化法测定S_(180)小鼠瘤组织中p53蛋白的含量并观察瘤细胞的病理形态。

One day 3 brother touch mice together, the old says: Present mice medicine also is used without giving thought to, I ate 3 packets to also do not have what thing yesterday, the second says grouchily: You eat medicine of 3 packets of mice what to calculate, should true kongfu just cries fierce, I now is the body with not bad King Kong, present mice clincher is right a bit action is done not have for me, like placing me to put a fart on my body just like mosquito.

有一天老鼠三兄弟碰在一起了，老大说：现在的老鼠药也不管用啊，昨天我吃了3包也没有什么事，老二不高兴的说：你吃3包老鼠药算什么啊，要有真功夫才叫厉害，我现在是金刚不坏之身，现在的老鼠夹子对我来说一点作用都没有，夹我一下就象蚊子在我身上放了个屁一样。

Methods: 100KunMing mice were divided into four groups randomly, each group included 25 mice inoculated EAC cells. The mice were treatedby celiac injection with saline solution , L-Arg , 5-Fu, L-Arg + 5-Fu respectively in each group . The natural survival time andthe average hydroperitoneum capacity were recorded for each group before the mice were killed.

将100只昆明小鼠随机分成4组，接种EAC细胞，依照分组向腹腔注射生理盐水、L-Arg、5-Fu、L-Arg+5-Fu，同时记录各组小鼠自然存活时间、处死时平均腹水量。

Results: a In the negative control group, spontaneous chromosome aberration and micronucleus rated the mice's were very low; in the positive control group, chromosome aberration and micronucleus rate of the mice's were highest. b Before cyclophosphamide intoxation, when the four kinds of vegetables and hilts juice were preventively irrigated into the mice's stomachs respectively, the chromosome aberration and micronucleus rate in the negative control group were lower than these in the positive control group (P.05); but after intoxation, when the four kinds of vegetables and fruits juice were therapeutically irrigated into the mice's stomachs respectively, the chromosome aberration and micronucleus rate were similar with the result above mentioned . c Acing the four kinds of vegetables and fruits, sea-buckthorn lad the best preventive and curative effects.

结果：a在阴性对照组中，小鼠自发的染色体畸变率和微核率极低；在阳性对照组中，小鼠染色体畸变率和微核率最高。b在环磷酰胺染毒之前，分别将4种蔬菜水果汁给小鼠进行预防性灌胃，其染色体畸变率和微核率均比阳性对照组低(P.05)；在染毒之后，分别将4种蔬菜水果给小鼠治疗性灌胃，其结果与上述实验结果相似。c在4种蔬菜水果中，以沙棘的预防和治疗效果为最好。

Animal models were worked out by injecting granule solution into the lung of mice through trachea to study pulmonary lesions in mice. All mice were intratracheally instilled every three days. At the tenth day, mice were sacrificed and. Lung organ coefficient, albumin, total protein, acid phosphatase and Alkaline phosphatase were measured.

为研究纳米二氧化钛对小鼠肺部的损伤，将小鼠采用非暴露式气管内注入法注入颗粒悬液建立动物模型，每隔2d染毒一次，在第10d处死小鼠，测定肺脏器系数及肺部组织中白蛋白、总蛋白、酸性磷酸酶和碱性磷酸酶的含量。

Methods Pregnancy mice were divided into four groups randomly. From the beginning of pregnance,the mice in experimental groups were given BPA with 30,120,360 mg·kg-1·d-1 until the new mice were born. The mice in control group were given the same volume of corn oil.

妊娠小鼠随机分成4组，从受孕第1天起实验组分别以30、120和360 mg·kg-1·d-1剂量溶于玉米油中的双酚A染毒至仔鼠出生，对照组用相同体积玉米油灌胃。

Passive transfer of sera from mice immunized with expressed G1 and G2 conferred partial protection or prolongation of time to death from fatal hantaan virus infection in infant mice which challenged with hantaan virus at 10LD50. The spleen cells from mice immunized with G1, G2and NP can protect or prolongate the lifetime of infant mice infected with lethal dose (10LD50 or 40LD50) hantaan virus.

将重组G1、G2和NP免疫小鼠的血清和脾细胞注入汉滩病毒致死性感染的乳小鼠体内，发现G1、G2的免疫血清和G1、G2及NP免疫脾细胞对乳鼠有保护作用，同时在一组试验中观察到G1的脾细胞可显著缩短乳鼠的存活时间。

It was found that during all three stages, the expression levels of Dnmt1 mRNA in the epithelial cells of the pregnant mice were significantly lower than those in the pseudopregnant mice (P.05), and the level of Dnmt1 protein expression in the pregnant mice was significantly decreased as compared with that in pseudopregnant mice at the 4-cell stage.

结果 Dnmt1蛋白主要表达于上皮层；妊娠组小鼠各期Dnmt1 mRNA表达水平均显著性低于同期假孕组(P.05)，妊娠组4细胞期Dnmt1蛋白表达水平显著性低于同期假孕组(P.05)。

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