查询词典 mice

Methods By intratracheally instillation, two strains of mice (C57BL/6 and C3H/He mice) were exposed to PM2.5 once time per day, for continuously two days.

采用气管滴注的染毒方法，两种品系的小鼠（C57BL/6小鼠和C3H/He小鼠）均予PM2.5染毒，连续染毒2d，最后一次染毒24h后，处死小鼠，取肺组织，并且立即置于液氮中保存。

Methods Forty C57BL/6 mice (female, 8 wk of age, 17 to 20 g body weight) were randomly divided into two groups (20 mice in each group): in the group V, bleomycin was injected intravenously once in a dose of 150 mg/kg, and in the group I, bleomycin was instilled intratracheally in a dose of 5 mg/kg, respectively.

8周龄雌性C57BL/6小鼠40只，随机分为静脉注射组20只、气管内滴入组20只，分别经尾静脉一次性注射BLM150 mg/kg和气管内滴入BLM5 mg/kg。

Finally,Tumorigenecity of KB-Neo,KB-PF4 and KBp17-70 cells wasassayed with xenograft tumor growth in isogenous nude mice by examiningthe growth speed of xenograft,survival span,and histochemistry ofxenograft nude mice.

最后，对重组的PF4和p17-70基因进行体内实验，建立裸鼠移植瘤模型，观察移植瘤的生长速度、移植瘤的体积、荷瘤鼠的生存时间、移植瘤瘤体组织中的血管密度。

Methods: According to the mechanism of cough reflex, the c-fibres's role in the respiratory system, and the principle of isosterism. Here, a peripheral antitussive LD was regarded as a lead compound. Amino functional groups, as substituents at the 1-hydroxy group of the racemate of LD, were introduced into the structure of the molecule. These novel compounds were confirmed by 1H-NMR, MS spectrum. Their antitussive activities were studied on mice in sequential method. The EDT50, the stimulating time that caused cough by NH3 on half of mice, were measured. Then could caculated the ratio R between the EDT50 of the treated groups and control group.

根据咳嗽反射的机制及C-纤维在呼吸系统的作用，以外周镇咳药左羟丙哌嗪为先导化合物，依据电子等排原理，在其结构中引入氨基以取代羟丙哌嗪分子中1位的羟基，设计一系列未见报道的化合物（01-15）；并采用了一条适宜的路线进行合成，通过1H-NMR、MS确证结构；采用&序贯法&实验进行新化合物的镇咳活性研究，动物模型采用氨水引咳小鼠，获得引致半数小鼠咳嗽的氨水刺激时间（EDT50）及给药组EDT50与对照组的比值R。

Considering the merits of in vivo studies in biotransformation i. e. activation or inactivation, protein-binding such as sex hormone binding protein , toxicokinetics, and more evaluative in hazard identification and risk assessment, we selected a battery of short-term and long-term in vivo studies, including uterotrophic assay in weaning mice and ovariectomized adult mice, an in vivo multiple endpoints assay, and a gestational and lactational exposure assay to identify the estrogenic effects of endosulfan on the offspring.

考虑到体内试验在代谢转化、血浆蛋白如性激素结合蛋白的结合、代谢动力学等方面比体外试验优越，在危害鉴定和危险度评定中更有价值，我们选择了多项体内试验，包括对幼年小鼠和卵巢切除成年小鼠的子宫增殖作用、对成年去势小鼠的体内多终点观察以及大鼠孕期和哺乳期接触对雄性子代生殖系统结构和功能的改变，即去雄性化或雌性化作用等，来验证硫丹的体内雌激素样作用。

Objective: To observe the changes of pathologic morphous and ultrastucture in the vastus lateralis of mice exposed to chronic hypoxia-hypercapnia. Methods: C57BL/6 mice were assigned randomly into control group and experiment group.

目的：观察慢性低氧高二氧化碳小鼠股外侧肌显微、超微结构的变化，探讨慢性低氧高二氧化碳对小鼠骨骼肌形态的影响。

AIM: To investigate the effects of goat placenta immunoregulating factor on the expression of costimulatory molecules lineaged T cells in BALB/c mice. METHODS: Animal model for immunodeficiency made from BALB/c mice with whole-body irradiation by 5 Gy 60Coγ-ray was applied for research.

目的：分析羊胎盘免疫调节因子对BALB/c小鼠T淋巴细胞共刺激表面抗原分子表达及其细胞因子分泌的影响，探讨羊胎盘免疫调节因子免疫促进作用机理。

To study the transcription expression law of Musclin gene and Lipogenic gene in muscle of the cadmium poisoning mice regulated by Vc. The experiment adopted RT-PCR detection method to study the variety of expression level of mice Musclin gene and Lipogenic gene (FAS, PPARγ, TGH).

为探讨维生素C调控Cd中毒小鼠骨骼肌中Musclin基因及生脂基因的转录表达规律，用RT-PCR方法研究小鼠Musclin基因及生脂基因(FAS、PPARγ、TGH)表达水平的变化。

Methods The experimental mouse was injected with high, middle, and low dosages of marasmius androsaceus po1ysaccharide 5, 10, 20 mg kg^(-1d^(-1) in the abdomen, and the comparison group was given the same volume of saline water i. p. once a day. After treatment for 14 consecutive days, the blood cell count instrument was used to measure the mice hemogram, the phagocytic function of peritoneal macrophage and the ability of carbon granular clearance were observed., the ability of the spleen lymphocytes proliferation was tested by MTT, and the hemolysin production test was used to evaluate the influence of MA polysaccharide on specific humoral immunity in mice.

小鼠腹腔注射不同剂量的鬼毛针多糖5， 10， 20 mgkg^(-1d^(-1)，对照组给予等量生理盐水，每天给药1次，连续14d后，用血细胞计数仪检测小鼠血象；用腹腔巨噬细胞吞噬鸡红细胞实验、碳粒廓清实验观察小鼠吞噬细胞的吞噬能力；采用MTT法测定小鼠脾T淋巴细胞增殖能力；采用血清溶血素形成实验观察鬼毛针多糖对小鼠特异性体液免疫功能的影响。

If it is true that the male mice are producing songs, it raises questions about how their sounds develop and whether mice - like birds - are able to learn new sounds, said animal communication expert Peter Marler, a behavioral neurobiologist at University of California, Davis.

如果雄性老鼠真的会&唱歌&的话，那么问题就是它们的声音是怎么发出来的，还有老鼠是不是也像小鸟一样能够学一些新的声音，动物沟通专家彼得·马勒说，他是美国加州大学戴维斯分校行为神经生物学家。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。