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The thesis chooses Dalian as the disquisitive object, which has all-important status in MICE economy in northeast region. then discussed the mode of development and strategies of Dalian′s MICE Tourism.

因而笔者选定了处于东北会展经济带龙头地位的大连作为研究对象，探讨了大连会展旅游的发展模式和发展策略。

ResultsResina Draconis had no obvious effects of decreasing the serum glucose level in normal mice, but could decrease the serum glucose level in alloxaninduced diabetic mice.

结果龙血竭提取物对正常小鼠空腹血糖无明显降低作用，能降低四氧嘧啶糖尿病模型小鼠的空腹血糖水平，能改善小鼠对蔗糖的耐受力，增加正常小鼠的胰岛素分泌，血清样本中有药物成分检出。

Results: the results showed that extracts of Artemsia dracunculus L. at the dose of 7.5%,3.75%,1.875% 20 ml/kg.w, can cause a signficant increase of WBC (P.05), thymus index, spleen index,(P.05) phagocytic rate and phagocytic index of phagocyte,(P.05) the transformation rate of the spleen lymphocytes,(P.05) and the serum IL-2(P.05),serum hemolysin concentration 50%( P.05)in immunodepressed mice. Conclusions: extracts oil from Artemsia dracunculus L. can significantly enhance the non-specific, cell-mediated and humoral immunological function in immunodepressed mice.

结果：与模型组比较，椒蒿挥发油各组均能升高小鼠外周血白细胞数(P＜0.05)；均能升高胸腺指数(P＜0.05)、脾指数(P＜0.05)；均能提高免疫受抑小鼠腹腔巨噬细胞的吞噬率，吞噬指数(P＜0.05)；均能升高脾淋巴细胞转化率(P＜0.05)；椒蒿挥发油各组血清IL-2值明显高于环磷酰胺对照组(P＜0.05)；椒蒿挥发油各组均可升高小鼠的血清半数溶血值(P＜0.05)。

MethodsThe behavior changes of learning and memory disorder induced by dysmnesia were observed on mice, related indexes were detected as well.Mice were divided into five groups randomly:normal group, control group, piracetam group, prepared Radix Rehmanniae high-dose group, PRR low-dose group.

方法对化学药品所致记忆障碍模型小鼠进行学习记忆行为实验并检测相关指标，实验动物随机分为5组，分别为：正常对照组、模型组、脑复康组(500 mg/kg)、熟地高剂量组(9 g/kg)、熟地低剂量组(4.5 g/kg)。

Methods The SPF mice were treated with MED or optimized MED in dose of 29.3 g/kg and 18.6 g/kg per day respectively by intragastric administration for five days continuously. And then, the various dysmnesia mouse models were prepared respectively with Scopolamine (3 mg/kg), Cycloheximide (120 mg/kg) by intraperitoneal injection and 40% alcohol (0.1 mL/10 g body weight) by intrag astric administration on the sixth day. Next day, memory result was estimated by using Step-down Test and Dark-avoiding Test after the mice were administered for half or an hour.

将强记汤及天然脑活素分别以 29.3 g/kg和 18.6 g/kg 的量每日经口灌胃给予 SPF 级小鼠，连续 5 d，第 6 天给药 1 h 后制备成记忆障碍模型，第 7 天给药 0.5~1 h 后分别用跳台法和避暗法测试记忆成绩；另用不同剂量（50 g/mL 和 150 g/mL）天然脑活素水煎液处理大鼠大脑 B104 CNS 神经细胞，以荧光素酶方法检测 CREB 表达水平。

Inductive interactions mediated by the Msx genes are essential for normal craniofacial, limb and ectodermal organ morphogenesis, and are also essential to survival in mice, as manifested by the phenotypic abnormalities shown in knockout mice and in humans.

基因敲除鼠和人类的畸形表现型的研究显示，Msx基因介导的诱导组织间的相互作用，对正常颅颌面、肢体和外胚层器官的形态发生至关重要。

METHODS: To construct recombinant expression plasmid subtype H1 of SIV HA gene of A/Swine/Guangdong/LM/2004(H1N1).BALB/c mice of 6-8 weeks old were immunized endemically with the recombinant plasmid.The splenocytes from the immunized mice were fused with Sp2/0 myeloma cells after the last immunization.

构建 H1 亚型猪流感病毒A/Swine/Guangdong/LM/2004(H1N1)HA基因表达质粒，基因免疫6～8周龄雌性BALB/c小鼠，加强免疫后取其脾细胞与骨髓瘤细胞 Sp2/0进行融合。

The mice inoculated with Coxiella burnetii intrana- sally developed interstitial pneumonia,while the primary pathological changes of mice inoculated intraperitoneally are granulomas in spleen and liver.2.The pathological changes became more severe followed the dosage increasing.3.Coxiella burnetii can be detected in spleen and liver at day 2 after inoculation.the lesion became more and more serious from day 2 to day 12.The characteristic changes were observed at day 7,and recovered at day 14. 4.The reticuloendothelial system are main target of Coxiella burnetii.The pathogen was detected in cytoplasm of monocyte -macrophages of spleen, liver, lung, and endothelioid cells of blood vessel. 5. Coxiella burnetii can be found in macrophages lysosomes by electron microscopy. Most of them are round or rod, and polymorphic shape can also be observed in different size.

结果：1、通过不同感染途径的实验证实，滴鼻感染的小鼠主要表现为间质性肺炎，而腹腔注射感染小鼠则以脾脏、肝脏肉芽肿为主要病变。2、通过不同剂量的感染实验发现，随着感染Q热立克次体剂量的加大，动物病变愈加严重。3、通过感染后不同时间的动态病理学观察发现，在腹腔注射后第2d的脾和肝脏即可发现病原体，主要脏器的病理变化从第2d到第12d逐渐加重，第7d动物的病变最典型，至感染后14d动物的受损器官已开始出现修复性变化。4、 Q热立克次体主要侵害机体的网状内皮系统，在感染小鼠的肝、脾、肺和外周血管单核巨噬细胞以及血管内皮细胞胞浆中查见病原体。5、透射电镜观察可见Q热立克次体主要位于巨噬细胞吞噬溶酶体内，呈多形性，多见圆形和杆状，大小不一。

Compared with control,①the mean tumor weight of H22 of SXKA Granules three dose groups were decreased significantly(P.01,P.05),and the mean inhibition rates of SXKA Granules 20、10 g/kg dose groups were above 30%;②the mean tumor weight of S180 of SXKA Granules three dose groups were decreased significantly(P.01),and the mean inhibition rates of SXKA Granules 20、10 g/kg dose groups were above 32%;③the mean tumor weight of EAC of SXKA Granules three dose groups were decreased significantly ( P.01, P.05),and the mean inhibition rates of SXKA Granules 20 g/kg dose groups were above 38%;④the mean tumor weight of Lewis carcinoma of SXKA Granules three dose groups were decreased significantly(P.01, P.05),and the mean inhibition rates of SXKA Granules 20、10、5 g/kg dose groups were above 36%;⑤the mean tumor weight of W256 of SXKA Granules three dose groups were decreased significantly ( P.01, P.05),and the mean inhibition rates of SXKA Granules 20、10 g/kg dose groups were above 32%;⑵Compared with control,SXKA Granules 20、10 g/kg dose groups had extended the survial time of the P388-bearing mice respectively(P.01),and the mean prolong rates of SXKA Granules 20、10 g/kg dose groups were above 50%;⑶Compared with S180-bearing group, SXKA Granules 20、10 g/kg dose groups could increase the weight of thymus and spleen, Spleen index and thymus index were increased, SXKA Granules 5 g/kg dose group could increase thymus index(P.05);⑷As Compared with control group, SXKA Granules 20、10 g/kg dose groups could improve mouse serum half hemolysis value depressed by transplanted tumor dramatically(P.01), which revealed the SXKA granules could improve the mouse humoral immunity system;⑸SXKA Granules 20 g/kg dose group could increase of englobe indexαon S180-bearing mice remarkably(P.01), which indicated the SXKA Granules could improve their cellular immunity system.

对荷W256大鼠，生兴克癌冲剂20、10、5 g / kg三组的平均瘤重明显低于对照组(P.01，P.05)，生兴克癌冲剂20、10 g / kg组的平均肿瘤抑制率均大于32 %；⑵与空白对照组相比，生兴克癌冲剂20、10 g/ kg能显著地延长移植小鼠白血病P388小鼠的存活天数(P.01)，生兴克癌冲剂20、10 g/ kg对荷白血病P388小鼠生命延长率均在50%以上；⑶与S180荷瘤组相比，生兴克癌冲剂对荷瘤鼠的免疫器官重量、胸腺指数和脾指数有一定的提高趋势，其中生兴克癌冲剂5 g / kg组对荷瘤小鼠的胸腺指数有一定的提高作用(P.05)；⑷与S180荷瘤组相比，生兴克癌冲剂20、10 g /kg组可提高由荷瘤引起的小鼠血清半数溶血素值的降低(P.01)，表明其可提高荷瘤小鼠体液免疫功能；⑸与对照组相比，生兴克癌冲剂20 g /kg组可提高荷S180肉瘤小鼠的免疫吞噬系数α值(P.01)，表明其可提高荷瘤小鼠细胞免疫功能。

Methods BALB/c mice were treated intragastrically by gavage with ST 3000?μm/kg.The mice were killed 1 hour,2 hours,4 hours,8 hours,16 hours after oral administration respectively for observing ependymal cells,neurons and endothelial cells of blood vessel of the lateral recess with transmission electron microscopy.

BALB/c小鼠，ST单次灌胃，分别于灌胃后1、2、4、8、16 h处死动物，用透射电镜观察外侧隐窝室管膜细胞、神经元、神经纤维和血管内皮细胞的结构变化。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。