查询词典 mice

Here, we show that mice genetically deficient in Toll-like receptor 5 (TLR5), a component of the innate immune system that is expressed in the gut mucosa and that helps defend against infection, exhibit hyperphagia and develop hallmark features of metabolic syndrome, including hyperlipidemia, hypertension, insulin resistance, and increased adiposity.

但美国Emory University的Matam Vijay-Kumar和Gewirtz等人在前人研究的基础上，意外的发现TLR5（Toll样受体-5）缺陷的小鼠较正常小鼠重20%，而且血甘油三酯、血胆固醇、血压及血糖偏高。TLR5缺陷的小鼠比正常小鼠进食多10%，经限制饮食后前者体重下降，但同时对胰岛素的反应下降；在经高脂饮食后前者体重快速增加并表现出&糖尿病&和&代谢综合征&表现。

The subsequent demonstration that the profound hyperphagia and obesity of ob/ob mice results from autosomal recessive mutation of the gene encoding leptin11, a hormone secreted by adipocytes, provided compelling evidence of a second adiposity signal.

ob/ob老鼠深刻hyperphagia和肥胖病起因于基因内码leptin11的autosomal隐性变化的随后示范， adipocytes藏匿的激素，假设第二个肥胖信号的确凿的证据。

Treatment with the mTOR inhibitor, rapamycin, ameliorated the hyperphagia, obesity, and the altered Pomc neuronal morphology in developing or adult Pomc-Tsc1cKO mice, and cessation oftreatment reinstated these phenotypes.

研究结果表明，mTOR信号会影响Pomc 神经元，过度活跃的mTOR信号会阻断机体的代谢异化功能，加上过度的摄取营养导致生物体产生肥胖症。

I was in a rock ruin, where rattlesnakes like to go because mice live there.

我去了一个废弃的石屋，那是响尾蛇爱去的地方，因为那里可能有老鼠之类猎物。

Results : We successful make MLL gene rearrangements construct by BAC engineering and finally had the transgenic mice.

结果：我们成功藉由BAC技术制造出MLL 基因重组架构。

Don at a high concentration（300 mg/kg） can significantly enhance the content of haemolysin in mice body.

在实验浓度范围内，半枝莲多糖对免疫抑制小鼠腹腔巨噬细胞吞噬功能未见明显增强效果；大剂量（300 mg/kg）半枝莲多糖能显著提高血清溶血素抗体水平，与是否脱蛋白无关。

Pedal swelling induced by 1% agar in mice, dermal c apillary hyper-permeability induced by histamine in rats were used to evaluate the anti-inflammatory of Kangning granules, and the clearance rate of intraveno us ch arcoal particles was used to study its effect on non-specific immunologic funct i ons. Serum haemolysin level and the number of antibody secretory cells in spleen were determined to assess its effects of specific immunologic functions.

运用小鼠足跖肿胀和大鼠皮肤毛细血管通透性实验观察其对炎症反应的影响；用碳粒廓清实验评价其对非特异性免疫功能的影响、测定免疫小鼠血清抗体水平和脾细胞抗体分泌细胞数量以评价感冒康宁颗粒对特异性体液免疫功能的影响。

The polysaccharides in Scutellaria barbata D.Don at a high concentration (300 mg/kg) can significantly enhance the content of haemolysin in mice body. Conclusion: The optimal process was applicable to the extraction of polysaccharides from Scutellaria barbata D.

在实验浓度范围内，半枝莲多糖对免疫抑制小鼠腹腔巨噬细胞吞噬功能未见明显增强效果；大剂量（300 mg/kg）半枝莲多糖能显著提高血清溶血素抗体水平，与是否脱蛋白无关。

METHODS:Observe the effect of SKR on immunity function in mice,the phagocytotic rate and phagocytotic index,haemolysin in serum,plaque forming cell,and the proliferation of splenocyte following administration SKR for 15 days.

以SK初乳素R-1连续灌胃给药15 d，测定小鼠增强小鼠炭末廓清能力、小鼠血清溶血素抗体水平、血清IL-2含量、抗体生成细胞数、脾淋巴细胞增殖能力等。结果：SK初乳素R-1各剂量组能增强小鼠炭末廓清率和廓清指数，各剂量组均能明显升高小鼠血清溶血素抗体水平(P.01)，提高小鼠血清IL-2含量(P.01)，促进小鼠抗体细胞形成(P.01)，增强ConA诱导的脾淋巴细胞增殖能力(P.01)。

ResultsIn the immune deficit mice ,1.33g/kg Naoshu capsule could enhance the phagocytic activity of monocytes, 0.67g/kg and 1.33g/kg Naoshu capsule could increase content of haemolysin antibody,and decrease footpad swelling induced by cyclophosphamide.

结果1.33g/kg脑舒胶囊能提高免疫低下小鼠单核巨噬细胞吞噬功能；0.67g/kg和1.33g/kg脑舒胶囊能增加免疫低下小鼠溶血素抗体生成，并拮抗环磷酰胺诱导的免疫低下小鼠足垫肿胀度减轻。

We are in a good position to meet your requirements.

我们完全可以满足你方的需求。

We are all pervade d with a sense of disaster.

我们普遍有大祸降临的感觉。