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Methods Eighty NIH mice were randomly divided into 8 groups, with 10 mice in each group.

80只NIH种小白鼠随机分为8组，每组10只。

Objective To explore the ageand gender of mice, the optimal dose of the dexamethasone phosphate and the optimal time of immunosuppression in the mice model applied for C.parvum oocyst infectivity and reproduce.

目的 探索适合隐孢子虫卵囊传代和扩增模型小鼠的性别、日龄、免疫抑制时间和免疫抑制剂地塞米松磷酸钠的最佳剂量。

The upward mice were inoculated with 2.0×105 oocysts, which were kept at the same time and with the same methods, in 4 ℃, 2.5 % potassium dichromate. 2 days after infection, mice feces were collected and oocyst were isolated and purified used saturated sucrose flotation.

以上各组每只小鼠感染保存时间和方法均相同的微小隐孢子虫卵囊的剂量均为2.0×105个，感染后第3天开始收集鼠粪，收集的鼠粪均用饱和蔗糖漂浮法分离纯化卵囊。

KM strain mice immunosuppressed with 7. 5～10mg/L DEX in drinking water had the higher oocysts output and fewer dead than other groups.(4) There was no significant difference infection rate between groups inoculated with different number CSO and groups inoculated CSO with conserved different time. Trial were divided into control, groups of 50mg/kg /d, 100 mg/kg /d and 200 mg/kg /d dose of the drug to study the anticryptosporidial activities of nitazoxanide in an immunosuppressed mice model. The experimental results showed the treatment with 200mg/kg bw /day was significant inhibition of oocyst excretion. To detect the two cryptosporidiums strain C.

实验结果表明：C.parvum虫种能够感染上本实验所采用的BALB／c和昆明小白鼠两种小鼠，而C.andersoni没有能够感染本次实验小鼠；且从小鼠感染后的排卵囊量和小鼠的生存状态来看，采用5～6周龄的KM鼠能获得最大量的隐孢子虫卵囊，小鼠的死亡数最少；每升饮水中地塞米松量为7.5mg～10mg组比12.5mg以上组小鼠死亡数量少，比5mg／L以下组排卵囊数量多；接种不同卵囊数和卵囊的保存时间这两个参数均对小鼠受感染后的排卵囊情况影响不大。

Objective: To study the relationship between donor blood derived allogeneic chimerism and levels of tolerance induced in the host mice, parabiosis between adult mice with H-2 complete difference was established.

摘 要：目的：探讨供体源的异基因血细胞嵌合体与受体耐受状态的关系，在不同品系的成年小鼠之间成功地建立了联体模型。

Department of Immunology, Beijing Medical University,Beijing 100083）Abstract:Objective: To study the relationship between donor blood derived allogeneic chimerism and levels of tolerance induced in the host mice, parabiosis between adult mice with H-2 complete difference was established.

摘 要：目的：探讨供体源的异基因血细胞孩子嵌合体与受体耐受状态的关系，在不同品系的成年小鼠之间成功地建立了联体模型。

The maintenance of parabiosis was observed in the other 6 pairs of parabiosis mice were observed. Mixed lymphocyte reaction and delayed-type hypersensitivity were observed and studied in the separated mice.

观察联体维持时间，并分别检测其混合淋巴细胞反应和诱导迟发型超敏反应。

When the parabiosis continued for 7 days, the parabiosised mice were separated and the level of transplantation tolerance was surveyed. Results : When the parabiosis continued for 7 days, the parabiosised mice were separated and their skins were transplanted from one to the other.

结果：联体小鼠在联体1 w后分开，同时进行相互间的植皮，发现Balb/c 小鼠对B6 小鼠的皮肤耐受期明显可以延长（MST＝25.7 d），而B6 小鼠对Balb/c 小鼠的皮肤耐受期无明显可以延长（MST＝11.9 d）。

To examine the influence of systemic factors on aged progenitor cells from these tissues, we established parabiotic pairings (that is, a shared circulatory system) between young and old mice, exposing old mice to factors present in young serum. Notably, heterochronic parabiosis restored the activation of Notch signalling as well as the proliferation and regenerative capacity of aged satellite cells.

为了查明系统因子对来自这些组织的衰老祖细胞的影响，我们在幼鼠和老鼠之间建立了共生态配对试验（即：一种共享的循环系统），给老鼠输入含有年轻因子的血浆，奇怪的是，异时性共生态细胞Notch信号重新激活，同时恢复了衰老干细胞增生和再生能力。

Evansi/HGPRT- could proliferate in the medium without HT and its pathogenicity to mice declined with the parasitemia and death of the inoculated mice to be delayed double than the control group.

生物学试验表明，HGPRT缺陷株在无HT的培养液中生长良好，对小鼠致病力有下隆的趋势，虫血症和小鼠死亡时间比对照组延长1倍多。

London based fashion photographer Matt Irwin might be is the next big thing in fashion photography.

总部位于伦敦的时装摄影师马特欧文可能会是下一件大事的时装摄影。

Based on IMC system,the response would be better if the model matched more satisfactorily.

由于系统基于内模控制设计，故模型匹配度越高，系统响应越好。