查询词典 mice

Methods Observation on the anti-inflammatory effects of 11-sodium deoxyglycyrrhetinic acid in three models i.e. induced mice's ear swelling, chronic granuloma by filter paper and air sac synovitis. The NOS activity and contents of PGE2 in mice serum and inflammatory humour were measured.

通过二甲苯致小鼠耳片肿胀、纸片致小鼠慢性肉芽肿及气囊性滑膜炎3个模型观察11-脱氧甘草次酸钠的抗炎作用，并测定小鼠血清和炎症液中前列腺素E2(PGE2)的含量和一氧化氮合酶活性。

Ex -cept the normal group, the mice in other three groups received sensitizat -ion by intraperitoneal injection of ovalbuminand challenge by inh -alation of OVA to induce bronchial asthma, The mice models of asthmaerwent with different therapy.

干预完成后，采用ELISA方法检测血清中IFN-γ水平，黄嘌呤氧化酶法检测肺组织中SOD活性，硫代巴比妥酸法测定肺组织中MDA含量。并对各组小鼠肺组织进行病理形态学观察。

OBJECTIVE:To observe hypoglycemic effect of Konjac Four in normal mice and alloxan diabetic mice.

目的：研究魔芋精粉的降糖作用。

ABSTRACT OBJECTIVE:To observe hypoglycemic effect of Konjac Four in normal mice and alloxan diabetic mice.

目的：研究魔芋精粉的降糖作用。

Objective To explore the effects of the dose and the way and times of administration of alloxan and body weight of mice in diabetic mice model.

目的 探讨四氧嘧啶剂量、给药途径、次数和小鼠体重对四氧嘧啶致小鼠糖尿病模型的影响。

The blood glucose level in normal mice and alloxan induced mice were significantly reduced.

用该品100mg/kg和400mg/kg给正常及糖尿病小鼠灌胃，测不同时间的血糖。

Purpose:In order to investigate the effect of pumpkin polysaccharide on normal mice and alloxan induced diabetic mice.

蒋滢 ，王彦英，孔庆胜目的：研究南瓜多糖对正常及糖尿病模型小鼠血脂的影响。

In order to study the relation of cytochrome P-450 with the protective action of SY-801 and SY-640 against 〓-induced UDS and 3H-BP binding to nuclear DNA, the effects of SY-801 and SY-640 on liver microsomal cytochrome P-450 were studied in mice. The results indicated that the liver microsomal cytochrome P-450 concentration and aminopyrine demethylase activity were significantly increased in mice pretreated with SY-801 150mg/kg or SY-640 150 mg/kg once daily for three days.

本实验进而观察了SY-801对小鼠肝微粒体细胞色素P-450酶系的影响，结果表明SY-801和SY-640体内连续给药3天，可诱导小鼠肝微粒体细胞色素P-450含量明显增加，同时氨基比林脱甲基酶活性亦明显增加；给药1次2小时内二者均可抑制氨基比林脱甲基酶活性，而对肝微粒体细胞色素P-450含量则无明显影响。

Unbeknownst to Amory, pharmaceutical giant Schering was simultaneously testing miglustat in rabbits and another strain of mice, and found the same results--contraception in the first strain of mice, but no effect in the other strain or other species.

Amory并不知道，制药界巨人Schering同时也对兔子及其他品系的小鼠进行了美格鲁特试验，而且得出了同样的结果――第一个品系的小鼠成功避孕，而在其他品系或种属则没有效果。

In summary, our results indicate that hypohidrosis is a frequent adverse effect in children with topiramate therapy. Younger age and hot weather rather than drug dosage are independent risk factors for topiramate-associated hypohidrosis. The resultes also rule out the possibility that topiramate act on its known mechanisms of action, such as potentiating GABA activity at GABAA receptors and antagonizing the AMPA/KA subtype of glutamate receptor in the secretory cells of sweat glands to inhibit sweat secretion. Our data also suggest that topiramate impairs sudomotor function in mice and leads to a significant reduction in AQP5 expression in sweat glands of anhidrotic mice, thus raising the possibility that dysregulation of AQP5 may contribute to topiramate related hypohidrosis.

综合全部实验结果，本研究提示：夏季和低龄是托吡酯引起泌汗障碍的主要危险因素，而托吡酯剂量对泌汗(来源：A44B8787C论文网www.abclunwen.com)功能的影响较小；托吡酯可以抑制小鼠汗液的分泌，小鼠的年龄并不影响这种抑制作用，但托吡酯对小鼠体温无明显影响；托吡酯并不是通过对GABAA受体及AMPA和KA两种谷氨酸受体亚型的作用而在汗腺分泌细胞抑制泌汗；托吡酯不影响汗腺形态及Na，K-ATP酶活性；汗腺分泌细胞的AQP5功能失调可能与托吡酯引起的泌汗障碍密切相关，而碳酸酐酶抑制作用并不是泌汗功能损害的主要原因。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。