查询词典 mice

The results showed that GP (320 mg/kg) combined with ADM (2 mg/kg) could significantly prolong survival Lime of mice bearing SF763 tumor, the life-prolonging rate was 88%(P40 mg/kg) significantly had a inhibition no A549 (P.05), the optium dosage of GP was 80 mg/kg, which had an inhibition of 82.2%(P.01) after an inoculation of 11 days; GP had a negative relation on prolonging survival time of mice bearing EC tumors between dosage of GP and the effect. The optimum dosage was 5-10 mg/kg, which had optimum prolonging rate of 32.77%(P.05). Thus GP could significantly prolong survival time of mice bearing SF763, A549 and EC tumors.

结果表明：生药剂量320 mg/kg GP联合2 mg/kg阿霉素，其生命延长率为88%(P01)，GP能明显延长荷人脑瘤SF763裸鼠生命；GP在大于40 mg/kg时对人肺腺瘤A549裸鼠具有明显的抑制作用(P.05)，最佳剂量为GP 80 mg/kg，接种时间11d，抑瘤率为82.2%(P.01)；GP对艾氏腹水瘤EC小鼠的生存期呈现负量效关系，GP最佳剂量范围在5~10 mg/kg，最高生命延长率为32.77%(P.05)。

The result showed HSV seropositive mice was really induced to produce tumor special or non-special factors, possibly included natural killer cell and lymphokine activated killer cell, which cooperated with mtHSV to kill tumor cells in course of mtHSV mediated tumor therapy. The effect in wtHSV seropositive mice was better than in mtHSV seropositive mice.

实验证明HSV免疫小鼠确实诱导产生了肿瘤特异性或非特异性因子，可能包括NK细胞和LAK细胞(lymphokine activated killer cell)，这些肿瘤特异性或非特异性因子在mtHSV介导的肿瘤治疗中与mtHSV一起协同杀死了肿瘤细胞，HSV-1F免疫小鼠的这种作用强于mtHSV免疫小鼠。

The experiment of BALB/c mice immunized with the DNA vaccines showed that pA and pEA could induce simultaneously specific antibodies against serotypes A, Asia1, and O FMDV, and the highest antibody titres were found in the pEA and inactivated vaccine groups compared to pA vaccinating mice. Compared with the control, the levels of IL-2, IFN-γ, IL-4, and IL-10 expression by splenic lymphocytes from mice immunized with pA and pEA were significantly increased.

小鼠免疫实验表明， pA和pEA免疫组的血清抗体均能分别与O型、A型和AsiaI抗原反应，与对照组相比差异较显著，且pEA免疫组和灭活疫苗免疫组抗体水平均显著高于pA免疫组；同时pA和pEA免疫小鼠细胞因子IL-2、IFN-g、IL-4和IL-10较对照组显著提高，且pEA免疫组的IL-2、IFN- g和IL-4水平明显高于pA免疫组。

Chapter Three. The Studies on Gene Therapy for Retinal Degeneration of the Mice and It's Mechanism Objective: To evaluate the abilities of adeno-associated virtus carrying the basic fibroblast growth factor gene as a therapy for retinal photoreceptors in slow retinal degerneration mice on the basis of the experiment results as mentioned above. Methods: On the born day of rds mice, IPE cells were isolated with enzyme-assisted microdissection from pigs and were cultured.

第三章 视网膜色素变性小鼠的基因治疗及其机制目的：在体外实验证明AAV载体可以高效安全转染IPE细胞并且可以表达具有生物活性的bFGF的基础上，应用AAV载体携带bFGF基因以先体外，后体内法和体内法两种方式进行视网膜色素变性鼠(retinal degemeration slow，rds)的基因治疗，在分子生物学、形态学和功能学上进行基因治疗的初步观察方法：在rds鼠出生的当天取眼球，采用酶辅助的显微分离方法分离培养IPE细胞。

Methods 16 female mice with alcoholic liver fibrosis were randomly divided into group A and B. The mice in group A(n=8) received syngeneic male bone marrow CD117+Lin- cell transplantation. The mice in group B(n=8) received isovolumetric Buffer 2 solutions infusion.

16只酒精性肝纤维化雌性小鼠随机分为移植组和对照组，移植组小鼠（n=8）接受同基因型雄性小鼠的骨髓CD117+Lin-细胞移植，对照组小鼠（n=8）接受等体积的Buffer2液输注。

Methods: nutmeg volatile oil gavage route of administration used to observe and calculate the value of LD50 in mice was observed in mice dose of pentobarbital sodium Excellency the hypnotic synergy strychnine convulsion convulsion caused by mice and the percentage of the incubation period, The incubation period the percentage of death and survival, as well as on coronary artery ligation in rats with acute myocardial infarction confrontation role.

肉豆蔻挥发油采用灌胃给药途径，观察并计算小鼠LD50值，观察对小鼠阁下剂量戊巴比妥钠的催眠协同作用，对士的宁引起小鼠惊厥的惊厥潜伏期及百分率、死亡潜伏期及存活百分率的影响，以及对冠脉结扎所致大鼠急性心肌梗死的对抗作用。

To understand the infectivity by porcine endogenous retrovirus with porcine skin fibroblast cell in vitro and in vivo, porcine skin fibroblast cell established by our laboratory were co-cultured with neo/HEK293 cell for the infection of RERV in vitro, and were subcutaneously transplantated to SCID (severe combined immuno-deficiency) mice for the infection of PERV in vivo, laying the foundation for valuation of biologic safety of xenotrans-plantation. The event of neo/HEK293 cells infected by PERV occurred during co-culture of porcine skin fibroblast cells with neo/HEK293 cells, expanding the rang of the infection of porcine endogenous retrovirus. Afterpig cells transplantated subcutaneously in SCID mice, the microchimerism (78.57%) of pig cells occurred widel, and there was phenomena of integration of PERV provirus (85.71%) in several organs or tissues remote from the injected sites, indicating infection of PERV in SCID mice in vivo. yet, there is no evidence of active viral replication in analysis of PERV env RNA of these tissues or organs.

为了解猪皮肤成纤维细胞PERV在体外和体内的感染性，通过建立猪皮肤成纤维细胞系，将所建细胞系与人胚胎肾293细胞体外共培养，并移植于严重联合免疫缺陷鼠皮下进行猪皮肤成纤维细胞PERV的体外和体内感染性实验，结果表明，猪皮肤成纤维细胞与人胚胎肾细胞共培养过程中，猪内源性逆转录病霉感染人胚胎肾细胞，进一步证实和拓宽了猪细胞PERV感染人细胞的范畴；猪皮肤成纤维细胞移植SCID鼠皮下后，导致SCID鼠发生猪细胞微嵌合(78.57%)和PERV在体内感染(85.71%)并且波及远离移植部位的多种组织或器官，但是并未检测出SCID鼠组织中表达PERV env RNA。

Construction of heavy chain transgenic mice and genome type analysis Linearized transgene plasmids were microinjected into pronuclei of zygotes from CBA×C57BL/6 mice, and transplamted into oviduct of pseudo-pregnant mice.

二、抗体重链转基因小鼠建立及基因型分析将线性化的质粒显微注射入CBA×C57BL/6小鼠的受精卵细胞的雄前核内，然后导入假孕雌鼠的输卵管。

To investigate the effect of EPO on hepcidin mRNA expression in normal mice,acute inflammatory mice and ACD mice,the acute phase model and ACD model of mouse was produced by subcutaneous injection of turpentine oil.

本研究探讨红细胞生成素在正常小鼠、急性炎症小鼠和慢性病性贫血小鼠模型中对hepcidin mRNA表达的影响。通过小鼠背部皮下双肩胛骨间脂肪垫内注射松节油的方法建立急性炎症模型和ACD模型。

The mice were randomly divided into two groups ( n =24 per group): the experimental group, the cultured cells were injected into the mice through the tail vein; the control group, the equivalent serum-free medium was injected. Six mice from each group were killed at 7, 14, 21, and 28 days after operation to receive HE staining, PCR gel electrophoresis, immunohistochemistry staining, and hepatic function detection.

将小鼠随机分为实验组和对照组（ n =24），实验组将诱导后细胞（1.6 × 105 个/只，含CD34+细胞1× 104 个）通过尾静脉注射入肝损伤小鼠体内，对照组注射等量无血清培养基，术后7、14、21、28 d 两组分别处死6 只小鼠，行HE 染色、PCR 凝胶电泳、免疫组织化学染色及肝功能检测。

Neither the killing of Mr Zarqawi nor any breakthrough on the political front will stop the insurgency and the fratricidal murders in their tracks.

在对危险的南部地区访问时，他斥责什叶派民兵领导人对中央集权的挑衅行为。

In fact,I've got him on the satellite mobile right now.

实际上 我们已接通卫星可视电话了