查询词典 mice

to investigate the effect of epo on hepcidin mrna expression in normal mice,acute inflammatory mice and acd mice,the acute phase model and acd model of mouse was produced by subcutaneous injection of turpentine oil.

本研究探讨红细胞生成素在正常小鼠、急性炎症小鼠和慢性病性贫血小鼠模型中对hepcidin mrna表达的影响。

The levels of nitric oxide and interferon-γ in spleen cell cultured supcrnatants of 3 kinds of infected mice were measured by using ELISA kit and Griess reaction. Results: On the 3rd day after infection, the parasitemia of DBA/2 mice was much lower than that of BALB/c and C57BL/6 mice.

结果：感染第3d之后，DBA／2小鼠的虫体血症水平显著低于BALB／c和C57BL／6小鼠；将疟原虫寄生的红细胞和脂多糖或IFN-γ分别与3种感染第3d小鼠脾细胞共同培养后，DBA／2小鼠脾细胞培养上清中的IFN-γ和NO水平明显高于BALB／c和C57BL／6小鼠。

RESULT: The activity and drinking of mice who had proceeded bone marrow transplantation after 60Co total body homogeneous radiation was no significantly different with normal mice, but their pelage became grey, blood samples detection were also same with normal mice after five weeks of bone marrow transplantation, the proportion of GFP positive cells in bone marrow cells achieved 59.62±13.21% proved by laser confocal microscopy, all these evidence proved the bone marrow reconstitution had been finished in the recipients.

结果： 60Co全身均匀照射后进行骨髓细胞移植的骨髓移植组小鼠的活动与饮食与正常小鼠无明显差别，只是毛发渐变灰白，五周后其血常规与正常鼠相较无明显差异，流式细胞仪检测显示其骨髓细胞中GFP阳性细胞的比例也达到59.62±13.21%，提示骨髓重建成功。

Recombinant expression vector k14/c-myc-paav was constructed bearing the mouse c-Myc cDNA derived by the skin specific human keratin 14 promoter, then the linear vector was microinjected into the two pronucleus of the C57BL/6 fertilized eggs to produce transgenic mice.256 microinjected eggs were transferred, 6 of the foster mothers were pregnant and 44 adult mice were produced, two of them were positive transgenic mice confirmed by PCR and Southern blot analysis, transgenic rate was about 4%.

以CMV-PAAV载体为基础载体，以皮肤特异人K14（人角蛋白14）基因启动子替换原质粒中的CMV启动子后，在其多克隆位点区依次插入鼠c-Myc基因的cDNA序列和gfp基因的编码序列，构建了高效表达c-Myc基因的真核表达载体。通过双原核显微注射技术，将线性化的载体DNA注入到C57BL/6小鼠受精卵的两个原核中，然后将注射后状态良好的胚胎移植到代孕鼠的输卵管中，共移植了256枚受精卵，6只受体怀孕，最终获得44只成年小鼠。

Firstly, normal mice was given orally by SM(qd×2d), and the dysbacteriosis were caused in them ,and then they were given orally by STM,these mice were formed experimental salmonellosis models ,finally these salmonellosis models were treated by bifidobacterium ,and count respectively the cfu/g of STM number in the mice excrement during different time of therapy,detect the index numbers of liver and spleen respectively, detect content of TNF-a in blood and in spleen respectively.

先用硫酸链霉素给正常小鼠灌胃2d，出现菌群失调症状，再用STM灌胃造成小鼠STM感染，使用两岐双岐杆菌液干预治疗STM感染小鼠，检测不同治疗时间各组小鼠粪便STM菌落数、肝脾指数、血及脾中TNF-a的含量。采用SPSS12.0统计软件包进行数据处理分析，统计学方法采用双因素重复测量资料的方差分析、单因素随机化设计的方差分析、卡方检验、多组均数比较的非参数秩和检验。结果：随着治疗天数的增加，STM菌落数逐渐减少，未干预组、生理盐水组及双歧杆菌组比较结果均为P＜0.01；组间比较，双歧杆菌组STM数下降最快。

Methods: Adult mice of Kunming variety were used as experiment animals. After judgement of oestrus, the oestrus period and oestrus stage were determined, and then those mouse were grouped depending on oestrus stage. The mice were dealed with diferrent dosage of PMSG and HCG to make them superovulation, afterwords were mated individually with the male mouse together at same cage. The embryoes were rinsed out and evaluated after 3.5 days when the plug had been seen. The transplant mice were born after the high-quality embryoes were transferred into the receptors mouse uterus at the same oestrus stage which was stimulated by mating with the male mouse which spermaduct had been ligated previously.

以昆明系小白鼠为实验动物，取性成熟个体，先进行发情鉴定，确定其发情周期及不同的阶段，然后按发情阶段分组，分别用不同剂量的孕马血清促性腺激素和人绒毛膜促性腺激素进行超排处理并与公鼠合笼，在见栓后的第3.5天冲胚，对所得胚胎进行鉴定；将质量较好的胚胎选出，移入同期发情并经结扎公鼠交配刺激后见栓的受体小鼠子宫内，得到移植小鼠。

Part three:Cochlear on Hair Cell Like Cells Regeneration in Presbycusis C57BL/6 Mice after Math1 Gene Inner Ear TransfectionIn order to test the probability of Mathl gene induces hair cell like cells regeneration in cochlea of presbycusis C57BL/6 mice,8 mounths old C57BL/6 mice were used for this study and were microinjected with Ad-MathlorAd-EGFP in the scala tympani by ventral approach.

第三部分老年性聋模型小鼠C57BL/6耳蜗鼓阶外源基因Math1导入后出现毛细胞样细胞现象的观察为了观察老年性聋C57BL/6小鼠(8月龄)耳蜗鼓阶外源基因Math1导入后能否在老年性聋的耳蜗微环境诱导出新生的毛细胞样细胞，为Math1基因治疗老年性聋进行探索性研究。

objective to study gastrodia elata blume to effect tau protein,sod,mda expression in gyrus hippocampi and cerebral cortex of experimental mice.methods to inject okadaic acid to mice ventriculus lateralis and to measure tau protein level,sod activity and lipid superoxide mda content of sod control group,oa injection group,oa and gastiodia elata injection solution group.results tau protein of experimental group(p＜0.05/p＞0.05),sod was lower than model group(p＜0.001) and was higher than control group(p＜0.05).conclusion gastrodia elata blume can increase sod activity and reduce tau protein expression and superoxide lipid forming in brain tissue of experimental dementia mice caused by oa.it can prevent and treat ad.

目的 观察天麻对痴呆模型大鼠海马、皮质神经元微管相关蛋白、超氧化物歧化酶和脂质过氧化物丙二醛表达的影响，探讨其治疗阿尔茨海默病(alzheimer disease，ad)的作用机制。方法用冈田酸(okadaic acid，oa)注射大鼠侧脑室造模，测定模型组、实验组、对照组海马和皮质tau蛋白、sod、mda的含量。结果实验组tau蛋白低于模型组(p＜0.001)，高于对照组(p＜0.05)；sod高于模型组(p＜0.001)和对照组(p＜0.05)；mda低于模型组(p＜0.001)，高于对照组(p＜0.05)。结论天麻可增强oa致实验性痴呆大鼠脑组织sod活性，降低mda蓄积和tau蛋白生成，具有防治阿尔茨海默病的作用。

To establish anaplasma artificial infection model in experimental animals which treated with dexamethasone to investigate the transmission route of the pathogen, mice were infected via intra-abdominal and subcutaneous inoculation with the blood from infected cattle, the homogenate of infected gadflies and viscera of infected mice, contacting infected mice, respectively, while rabbits were infected through co-feeding with affected cattle.

采用地塞米松注射液长期抑制试验动物的免疫力，通过小鼠腹腔、皮下接种含有无浆体病原的奶牛血液、阳性厩蝇内容物、脏器悬液，并进行阳性小鼠接触感染和兔子临床同层感染等试验，研究奶牛无浆体的感染和传播及在试验动物体内的消长规律，建立起无浆体人工感染模型，调查临床中病原体的实际传播途径。

R. ChinaAbstract:Objective To study antiradiation and antifatigue effects of a soft capsule mainly composed of cistanche,acanthopanax senticosus and jujube. Methods The mice were divided into four groups and then orally given soft capsule at doses of 0 .0g/kg.bw, 0.18g/kg.bw, 0.36g/kg.bw, 1.08g/kg.bw for a successive period of 30 days.The burden-swimming time , hepatic glycogen, serum urea nitrogen, lactic dehydrogenase of mice were observed. The mice were divided into four groups and then was orally given soft capsule at doses of 0 .0g/kg.bw, 0.18g/kg.bw, 0.36g/kg.bw, 1.08g/kg.bw for a succession of 21 days.

设立3个实验组，每天分别以0.18、0.36和1.08g/kg·bw剂量的软胶囊给小鼠灌胃一次，同时设立空白对照组，连续灌胃30d后，测定小鼠的负重游泳时间、肝糖原含量、运动后血清尿素水平、血乳酸曲线下面积等指标，以测定其抗疲劳作用；每天以上述剂量给小鼠灌胃，同时设立一个辐射对照组，连续灌胃21d后，不同指标选择不同的照射剂量，各组均以同一剂量γ射线全身照射一次，照射后继续给予样品。

Given the language of section 102(2), the Supreme Court's rejection of substantive review under NEPA seems unjustifiable in principle

按照第102条的规定，最高法院否决《国家环境政策法》所规定的实质性复审在原则上似乎是不正当的。

ObjectiveTo explore the effect of variable hip abduction orthosis on children spastic cerebral palsy.

目的探讨髋关节矫形器在儿童痉挛型脑性瘫痪康复中的作用。