查询词典 mice

Prepare 131I-labbelled anti-CD20 monoclonal antibody using lodogen iodine labelling;(2)Measure the immunity activation of labbelled antibody by means of both cell combine analysis and LDH cytotoxicity detection kit;(3)Evaluate the injury rate of tumor exposed to 131I-chimeric anti-CD20 monoclonal antibody in vitro. The MTT method and the experiment of cell growth control are used;(4)Record the apotosis of Daudi cell using gelose electrophoresis;(5)Learn the inhibition effect of radioactive medication on the marrow. Radiohnmunoimages are taken on various intervals after injection of the labeled antibodies to the nude mice. The distribution of radioactive medication, I31l-labeled antibodies, in the marrow tissue indicates the inhibition effect. Here a B cell non-hodgkin lymphoma model in nude mice is established by us;(6)28-day observation are done in 3 groups of nude mice model.

(1) 用lodogen标记法制备131I-国产人鼠嵌合抗CD20单抗；(2)采用细胞结合分析法和乳酸脱氢酶法细胞杀伤性实验测定131I标记后国产人鼠嵌合抗CD20单抗与靶细胞的免疫活和利结合能力；(3) MTT法和细胞生长抑制实验测定131I-国产人鼠嵌合抗CD20单抗的体外杀瘤活性；(4)用琼脂糖凝胶电泳法研究131I-国产人鼠嵌合抗CD20单抗致Daudi细胞凋亡；(5)建立荷人B细胞淋巴瘤移植瘤裸鼠模型，应用γ计数法检测注射到荷瘤裸鼠体内的131I-国产人鼠嵌合抗CD20单抗的组织分布情况，明确其靶向性；(6)将荷瘤裸鼠分3组进行放射免疫治疗，分别为阴性对照组、131I-国产人鼠嵌合抗CD20单抗组、国产人鼠嵌合抗CD20单抗组。

Compared the effects of anti-inflammatory and analgesia by testing small mice with the hot-plate procedure and the writhing test and the auricular intumesce of tested small mice as well as the toe intumesce of tested big mice.

结果：二者对热板法小鼠的痛阈值均无提高，均能减少酒石酸钾所致小鼠扭体次数，对二甲苯所致小鼠耳廓肿胀和角叉菜胶所致大鼠足趾肿胀具有抑制作用，但二者之间比较差异无显著性。

Methods Kunming mice and C57BL/6 mice were adopted. The irritative train offootplate shock was combined with a tone signal for check the difference of fear memoryformation in different shock intensity and in different species mice, in identical condition training.

方法选用昆明种和C57BL／6小鼠，将足底电击刺激的训练与声音相结合，观察同一品种小鼠用不同电击强度以及不同品种小鼠用相同条件训练时，恐惧性记忆建立的差异。

Cholesterol gallstones formed in C57L mice and fatty livers developed in AKR mice. Conclusions Biliary cholesterol hypersecretion is the key pathophysiological defect of gallstone formation, lith genes have effects on biliary cholesterol hypersecretion and susceptibility to cholesterol gallstone formation in C57L mice. Lithogenic bile is formed at the canalicular membrane and precedes the development of cholesterol gallstones. It is most likely that cholesterol and bile acid hyposecretion make the AKR strain susceptible to the development of fatty livers and resistant to gallstone formation.

结论胆道胆固醇的高分泌是胆囊胆固醇结石形成的主要病理生理基础，结石基因决定了C57L鼠肝内胆汁中胆固醇的高分泌和胆囊胆固醇结石的易患性，成石胆汁形成在肝内胆管，先于胆囊结石的形成；肝内胆汁中胆固醇和胆酸的低分泌可能与AKR鼠脂肪肝的发生和胆囊结石的免患性有关。

Methods and Results— To test this hypothesis, we generated transgenic mice with cardiac-specific oerexpression of DGK . There were no differences in heart size and heart weight between DGK -TG and wild-type littermate mice. The left entricular function was normal in DGK -TG mice.

方法和结果：为验证此假说，实验采用过表达心肌特异DGK的转基因小鼠，其心脏大小及重量与野生型同窝别小鼠无差异，左室功能亦正常。

Candida colonisation did not enhance oalbumin permeation in mast cell deficient W/W mice but did in congenic littermate control +/+ mice. Reconstitution of mast cells in W/W mice by transplantation of bone marrow deried mast cells restored the ability to increase oalbumin permeation in response to Candida colonisation.

念珠菌定植不加强肥大细胞缺陷W/W小鼠的蛋白通透性，而其同系同窝对照+/+小鼠则有加强，W/W小鼠通过骨髓肥大细胞移植重建肥大细胞功能可恢复念珠菌定植后对卵白蛋白通透性的增强作用。

Using ST1KO mice, we have demonstrated that early B lymphopoiesis is impaired in the absence of STAT1, including reduced numbers of pro-B, pre-B, immature-B, and mature-B cells in BM. Interestingly, B220+CD138+ cells of ST1KO mice are also significantly decreased in BM as apposed to WT mice.

在本论文中，我们发现STAT1基因剔除小鼠的早期B淋巴球发育，不论在pro-B， pre-B， immature-B，或mature-B时期皆有明显的缺陷；特别的是，STAT1基因剔除小鼠的骨髓细胞(B220+CD138+)则有明显减少的现象。

In order to develop a safe and effective immunoadjuvant to enhance the immunity and resistance of animals against infection, a novel CpG Oligodeoxynucleotides containing 11 CpG motifs was synthesized and inserted into the VR1012 plasmid, designated as VR1C. Then the recombinant VR1C was entrapped with Chitosan nanoparticles prepared by the method of ionic cross linkage, and employed to inject muscularly 3-weeks old Kunming mice; the blank VR1012 packed with CNP and saline were used to inoculate mice as the control groups. 28 days after inoculation, all mice were orally fed with 0.4ml 2x108CFU/ per mouse virulent hemorrhagic enteritis E. coli to challenge the resistance against infection.

为研制安全高效免疫调节剂增强动物免疫抗病能力，本实验设计合成含11个C pG基序的寡聚核苷酸，重组构建含CpG的VR1012质粒(VR1C)；制备壳聚糖纳米颗粒包裹重组质粒(CNP-VR1C)，肌注接种3周龄昆明小白鼠，设壳聚糖包裹空质粒和生理盐水对照组；接种后28天口服大肠杆菌攻毒观察小鼠天然免疫的变化和对强毒感染的抵抗力，Sandwich ELISA测定血清免疫球蛋白和白细胞介素含量。

Experiments were performed in three groups of mice,20 minutes later ,mice in control group were treated with 2ml PBS by ultrasonic nebulization for 20 minutes, mice in treatment group were treated with rhIL-10(10ng) by ultrasonic nebulization for 20 minutes.

结果：经DNA测序证实，克隆的hIL-10cDNA与文献报道的一致，应用ELISA方法检测证明在大肠杆菌中成功表达出了hIL-10，含量＞400pg/ml，检测其生物学活性与标准品无明显差异。

Lucidum spore were given orally to CsA immunosuppression model mice, and the phagocytic function of macrophage and neutrophile, total hemolytic complement, weight of immune organs of the experimental mice were detected on the 2nd and 20th days after the withdrawal. Results: In mice of high, middle, and low dosage subgroups of G.

用不同剂量赤灵芝孢子粉对环孢素A模型小鼠灌胃，于停药后第2、20天分别检测小鼠腹腔巨噬细胞和中性粒细胞的吞噬功能、免疫器官重量及血清总补体活性(CH50)。

According to my definition, the Manchurian Candidate is an experimentally created dissociative identity disorder that meets the following four criteria

根据我的定义，满州候选人是一个创造分离身份混乱的实验，它符合下述的4条标准

I'd be chuffed to play at a World Cup, but I have many years ahead of me in the game so I hope to have more opportunities.

我会chuffed发挥在世界杯，但我有很多年的比赛在我前面，所以我希望有更多的机会。