查询词典 methylglycine

To date, there have been a few clinical trials exploring the efficacy of NMDA enhancers as adjuvant therapy. For instance, D-serine (an endogenous agonist of the NMDA-glycine site) and sarcosine (N-methylglycine, an endogenous glycine transporter I inhibitor) are not only well-tolerated but also synergistic in improving positive, negative symptoms and cognitive function in chronic patients receiving typical or atypical antipsychotics. We just completed the first trial applying NMDA enhancers in acutely exacerbated schizophrenia patients with collaboration with Harvard University, and the results showed that sarcosine was superior to D-serine in efficacy.

目前已有将NMDA促进剂作为辅助用药的临床研究，例如，D-serine (一种内生性NMDA-glycine site致效剂)、sarcosine (即N-methylglycine，一种内生性glycine transporter I 抑制剂)等，结果显示它们不但安全，且能加强传统及新一代抗精神病剂对慢性患者活性、负性症状及认知功能的疗效；我们日前与哈佛大学合作完成目前唯一将NMDA促进剂用於急性患者的研究，结果发现，sarcosine的疗效又优於D-serine。

Different from the Prato reaction of C〓, the direct reaction between C〓 and N-methylglycine only provided two positional isomers at the expense of the third.

和液相反应相比，在C〓和N-甲基甘氨酸的反应中，加成只发生在C〓的1，2-和5，6-位置。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。