查询词典 methylation

To establish time-efficient and sensitive method for detection of the methylation of FMR1 and XIST genes,genomic DNA was deaminated by sodium bisulfite.

建立一种快速、灵敏的检测脆性X智障基因（fragile X mental retardation，FMR1）、X染色体失活基因（X chromosome inactivation，XIST）甲基化的方法。

During this study, the researchers measured the degrees of methylation in tissue remoed from 47 patients who had undergone mastectomies for a form of breast cancer called inasie ductal carcinoma.

此研究中，研究者测定了47个患浸润性导管癌而作乳房切除术病人的切除组织的甲基化程度。

Recent progress of dimethyl carbonate which acted as methylating reagent in methylation reaction s that took place on carbon, oxygen, nitrogen and sulfur atoms was reviewed.

综述了碳酸二甲酯作甲基化试剂在碳、氧、氮和硫原子上进行甲基化反应的研究进展，提出了今后研究工作的发展方向。

cDNA microarray was an effective and useful method to survey gene expression profiles in pancreatic carcinoma. MBD1、EDG1 and its hyper methylating modulation may play an important role in the pathogenesis of pancreatic cancer, among which the high expression of MBD1 in pancreatic cancer would be the key modulating point in the down regulation of multiple methylation related suppression genes transcription.

cDNA微列阵技术为胰腺癌相关基因表达谱的分析提供了有力的工具，MBD1、EDG1等基因过甲基化表达调控可能在胰腺癌发病机制中起着关键作用，而MBD1在胰腺癌中高表达可能是多个甲基化相关抑癌基因转录表达下降的关键调控点。

MBD1、EDG1 and its hyper methylating modulation may play an important role in the pathogenesis of pancreatic cancer,among which the high expression of MBD1 in pancreatic cancer would be the key modulating point in the down regulation of multiple methylation related suppression genes transcription.

cDNA 微列阵技术为胰腺癌相关基因表达谱的分析提供了有力的工具，MBD1、EDG1等基因过甲基化表达调控可能在胰腺癌发病机制中起着关键作用，而MBD1在胰腺癌中高表达可能是多个甲基化相关抑癌基因转录表达下降的关键调控点。

The specific inhibitor of DNA methylation that is available currently is 5-Aza-2'-deoxycytidine (5Aza-dc), which forms a covalent bond with the DNA methyltransferase, thus, limiting the number of free DMT molecules for methylating DNA and then decreasing its biology activity.

目前研究较多的甲基化抑制剂是胞苷类似物5-氮杂-2'-脱氧胞苷(5-Aza-2'-deoxycytidine， 5Aza-dc)。5Aza-dc的作用机制是与DNA甲基转移酶共价结合，降低酶的生物活性。

It is known that one of the important mechanisms for epigenetic reprogramming is DNA methylation.

目前的研究认为这些异常是由于体细胞核在去核卵母细胞中重编程错误造成的，导致克隆牛胚胎的发育潜能降低。

Results The 5'CpG island methylation in the core promotor of ING1b gene was detected in HT29 human colon cell line, and tunned to demethylation after treatment with Aza and TSA.

结果 HT29人结肠癌细胞株ING1b基因核心启动子区域存在CpG岛半甲基化，且乙酰化水平低，mRNA表达水平低。

In this experiment, we associated themethylation-sensitive single-strand conformation polymorphism analysis withlaser-induced fluorescence capillary electrophoresis to set up a new method which isfast separation, high sensitivity, and automated for detection of DNA methylation.

本研究通过甲基化敏感的单链构象分析法与毛细管电泳技术相结合建立一种高效、灵敏、自动化的DNA甲基化检测方法。

Existance of high risk factors at de novo diagnosis didn't corelated with the Id4 methylation status.

DNA抑制因子4甲基化与ALL患者初诊时是否具有高危因素并不完全相关。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。