查询词典 methylation

Studies show that DNA abnormal methylation is one of the important ways to inactivate P15INK4b gene.

因此，针对P15~(INK4b)抑癌基因的去甲基化治疗成为恶性血液病防治的一条新思路。

DNA methylation is one of the important mechanisms that lead to the inactivation of tumor suppressor genes.

在癌变的过程中抑癌基因表达的改变可能首先表现DNA甲基化状态的异常。

Methylation of promoter in p16 gene is one of the important mechanisms of the inactivation of the gene.

喉癌中p16基因的甲基化是该基因失活的重要机制之一，p16基因的失活与喉癌的发展和演进密切相关。

Ingle nucleotide polymorphism genotying and deoxyribonucleic acid methylation are significant in molecular biology, but their tradition analyse methods have some limitations, and liquid chromatography - mass spectrometry are favourable for analyzing them.

NP分型和DNA甲基化在分子生物学中具有重要的研究意义，但它们传统的分析方法存在较大的缺陷，而液-质联用技术在SNP分型和DNA甲基化分析中显示出良好的应用前景。

One intriguing unknown is whether methylation of genes triggered by exposure to fat is inheritable.

有趣的是，接触到脂肪引发的甲基化基因是否可以遗传，我们还不得而知。

The results showed that mutation of the Kail gene,methylation of CpG islands and the abnormity of p53 are not related to low expression of Kail.

实验结果表明：基因点突变、启动子CpG岛甲基化、p53蛋白异常与Kai1基因表达下调不存在相关性。

In conclusion,this research has gotten some significant results:firstly Kail gene is highly related with the metastasis potential of colorectal carcinoma cells,secondly mutation of Kail gene,methylation of CpG islands in the promoter and abnormal expression of p53 have no important effects in the down-regulation of Kail gene.

本研究结果表明：Kai1基因与大肠癌细胞转移潜能有关；基因点突变、启动子CpG岛甲基化与p53异常在Kai1基因表达下调中不起重要作用。

The results indicated that Kail/CD82 is higher expressed in HT29 and SW480 than in LoVo and HCT116 whatever in mRNA or protein level.The possible mechanism of down regulation of Kail was also analyzed. By PCR-SSCP,8 exons of Kail,exon 3 to exon 10,were screened in LoVo and HCT116 cell lines. The methylation of CpG islands in promoter region was analyzed,and the expression level of p53 was detected by IH and Western Blot.

为进一步探讨Kai1基因表达下调的机制，本研究用PCR-SSCP技术分析了Kai1／CD82表达较低的LoVo与HCT116细胞系的Kai1基因第3～10外显子是否存在点突变，检测Kai1基因启动子区域CpG岛的甲基化状况，并用免疫组化与Western Blot等方法研究Kai1基因表达与p53异常之间的相关性。

The formation of 1,3- and 1,6-DMC resulted from methylation at ring carbon 3 and 6, which have identical reaction activities, in 1-methylcarbazole in kerogen matrix with identical rate. The 1,4- and 1,...

相对于1，3-DMC和1，6-DMC而言，1，4-DMC和1，5-DMC显示出相当一致的变化趋势，表明了在1-甲基咔唑进一步的甲基化中，3、6与4、5环碳位上存在竞争性反应过程。

DNA methylation is an important modifiable manner of epigenetic dominating the correct expression of gene. It is a main instrument of regulating genome function and plays a prominent part in the embryonic normal development.

DNA 甲基化是支配基因正常表达的一种重要的表观遗传修饰方式，是调节基因组功能的重要手段，在胚胎的正常发育过程中具有显著作用。

But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊！不用提了。提到肉，真是糟透了。