查询词典 methylate

Methylation is negative correlation with genetic transcription , and the mechanism is probably as follows : directly interfere the combination of specific transcripton and recognition site of each promoter ; mediated transcription inhibition by change the construction of chromatin; induced gene silencing by combination of methylation site and transcription inhibition. P16 gene is also called multiple tumor supresser gene , which is the best easily to methylate in the anti-oncogenes. P16 gene locates in 9p21 of mankind-chromatosome , and it's total length is 8.5kb .

甲基化与基因转录呈负相关，其机制可能是[3]：直接干扰特异的转录子和各自启动子识别位点的结合；通过改变染色质结构，介导转录抑制；甲基化DNA位点直接与转录抑制子结合，诱导基因沉默。p16基因又称为多肿瘤抑制基因( multiple tumor suppressor 1 ，MTS1) [4] ，是肺癌中最易发生甲基化的抑癌基因，该基因位于人类染色体9p21上，全长8.5kb ，由两个内含子和三个外显子组成。

This thesis deals with the investigation on the chemical constituents of Dioscorea Opposite Thunb and studys the interactions between 5,7-dihydroxy-4′-methoxy flavanone,-epicatechin and bovine serum albumin using fluorescence, electrochemical method ,UV absorption and NMR spectroscopy. The main contents are as follows: Chapter 1: Study of the chemical constituents in Dioscorea opposita Thunb 1. Two methods were used to methylate the fatty acid in Dioscorea opposita Thunb.

本文在前人的工作基础上对我省道地药材-怀山药饮片中的化学成分进行了系统的研究；同时利用核磁共振方法、电化学分析法、荧光光谱法、紫外光谱法分别研究了两种天然酚性化合物5，7-二羟基-4′-甲氧基二氢黄酮，(--表儿茶素与牛血清白蛋白之间的相互作用，主要内容如下：一。

From the reaction mechanism, which involved formation of benzodiazepinium ethoxycarbonylmethylate, the reaction mechanism, which involved formation of benzodiazepinium ethoxycarbonyl- methylate followed by cycloaddition reaction, was tentatively proposed.

通过研究反应过程中分离出的副产物反丁烯酸二乙酯III和4，5-二氢吡唑-3，4，5-三羧酸乙酯IV，初步提出了反应经过乙氧羰基甲基化苯并二氮杂卓翁中间体V再发生环加成反应的机制。

Methods:202 lying –in women were randomly divided into two set ,observing a group was 102 ,contrasting a group was 100,pitocin 20U was used by adding 50g/L glucose nomal salines 500ml dripping in two groups after childbirth ,at the same time with administering carboprost methylate suppository 1mg via the rectum (depth 6cm is suitable)in the contrasting a group.

202例产妇随机分为两组，观察组102例，对照组100例，两组产妇均在胎儿娩出后立即用缩宫素20 U 加入50g/L 葡萄糖生理盐水500ml 静滴，观察组与此同时用卡孕栓1粒（1mg ）置入直肠内（深度6cm 为宜）。

Magnesium methylate can be prepared by reacting magnesium with dry methanol; Primary alcoholates can be prepared by alcoholysis; the sterically demanding substituted magnesium alcoholates can be prepared by ester exchange or from dialkylmagnesiums.

综上所述，几乎所有的醇镁化合物都可以通过这三种方法进行制备：甲醇镁通过直接合成法制备；伯醇镁通过醇解法制备；仲醇镁或叔醇镁通过酯交换或烷基镁法制备。

The synthesis path of 2-phosphono-butane-1,2,4-tricarboxylic acid is studied by using alkyl phosphate,butendioic acid dialklesters and methyl acrylate with the catalyst of sodium methylate.

论文摘要本文以亚磷酸二甲酯，顺丁烯二酸二甲酯，丙烯酸甲酯为原料，甲醇钠为催化剂，合成了 2-膦酸丁烷-1，2，4-三羧酸并对中间物及产物进行了 IR、13C，31P 核磁，MS 表征。

Silicon phthalocyanine dihydroxide was prepared from silicon phthalocyanine dichloride through two methods. The first was alkali treating that meaned silicon phthalocyanine dihydroxide was treated in the ethanol solution containing sodium methylate .The second was acid treating meaned precipitating its solution in concentrated sulfuric acid into ice water. The product yield of the second method was 77.0％, which was higher than the method of alkali treating.

此外将合成的二氯酞菁硅采用两种方法转化为二羟基酞菁硅，第一种方法是碱处理法即将二氯酞菁硅在甲醇钠的乙醇溶液中回流得到，最高收率为53％第二种方法是酸处理法即采用二氯酞菁硅的硫酸溶液在冰水析出的方法转化为二羟基酞菁硅，其中酸溶析出法收率为77.0％。

The cis-9, trans-11-CLA was extracted with hexane-isopropanol,methylated with methanol-sodium methylate and cis-9,trans-11-CLA was separated and quantified using gas chromatography.

样品经正己烷-异丙醇提取、甲醇-甲醇钠甲酯化后，进行气相色谱分析；采用程序升温，以保留时间定性，外标法定量。

And a glycochain IbGpl-OL-LbGp5-OL has been found out by the way of Pronase E or β elimination reaction to dissociate the glycochain from the molecules of glycoconjugate and through the separation and purification of it by gel column chromatography, and ion exchange ohromatography and then its repetitive unit construction has been tested by the ways and means of full hybridization and partial acid hydrolisis, methylate analysis, Gc, Gc/Ms, iH and 1/3 CNMR.

通过链霉蛋白酶E或β-消去反应等方法，将糖链从糖缀合物分子上解离下来，经凝胶柱层析或离子交换柱层析进行分离、纯化得到相应的糖链LbGp1-OL～LbGp5-OL。

The method on trans fatty acids analysis in food is very important. The effects of methylate sodium, potassium hydroxide, sulfuric acid and boron trifluoride in methanol and their different concentration and dosage on TFA analysis were studied. The chromatographic condition and the influence of time and temperature on the esterifation of TFA using boron trifluoride in methanol were optimized. A method for analyzing TFA were established by GC based on boron trifluoride in methanol and RT-2560(100m×0.25mm×0.2μm) capillary column.

研究了甲醇钠－甲醇、氢氧化钾－甲醇、浓硫酸－甲醇和三氟化硼－甲醇4种甲酯化试剂的浓度、用量及甲酯化时间和温度对反式脂肪酸检测的影响，优化了色谱条件，建立了以三氟化硼－甲醇法甲酯化，RT-2560(100m×0.25mm×0.2μm)毛细管柱为基础的反式脂肪酸气相色谱检测方法，C18：1-9 t， C18：1-11 t， C18：2-9 t， 12 t和C22：1-13 t 4种反式脂肪酸的最小检出浓度在0.774.08 mg/kg之间。4种反式脂肪酸不同添标浓度回收率为98.44%101.23%，重复测定的相对标准差在0.22%1.31%之间，有较好的准确度和重现性。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。