查询词典 methyl-glyoxal
- 与 methyl-glyoxal 相关的网络例句 [注:此内容来源于网络,仅供参考]
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AIM To study the role of N-methyl-D-aspartic acid NMDA and non-NMDA receptors in processing nociceptive visceral information in the spinal cord.
目的 研究NMDA N-methyl-D-aspartic acid和非NMDA受体在介导脊髓内脏痛传入中的作用。
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Tetrahydroisowuinolin derivatives and phthalide derivatives were designed and synthesized on the basis of a PDE4 inhibitor pharmacophore model set up through computer simulation. Some tetrahydroisowuinolin derivatives synthesized were evaluated on their activity against PDE4 for study on the structure-activity relationship.(7-cyclopentyloxy)-6-methoxy-3,4-dihydroisoquinolin-2(1H)-yl(4-hydroxy-3-methoxyphenyl)methanone (155) and Methyl 7--6-methoxy-2-(4-methoxy- benzoyl)-1-phenyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylate (170) showed good activity against PDE4, which were chosen as the lead compounds to design and synthesize another analogs in order to develop selective PDE4 inhibitors with better activity.
分别设计合成了以四氢异喹啉和氨基苯酞为骨架的两类小分子杂环化合物,并对部分四氢异喹啉衍生物测试了其相关的生物活性,初步确定了其构效关系,发现了两个对PDE4有较好抑制活性的先导化合物(7-cyclopentyloxy)-6-methoxy-3,4-dihydroisoquinolin-2(1H)-yl(4-hydroxy-3-methoxyphenyl)methanone (155)和Methyl 7--6-methoxy-2-(4-methoxy- benzoyl)-1-phenyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylate (170)。
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Quinolinic acid is an endogenous neurotoxin, that activates the N-methyl-D-aspartate receptor and the biosynthesis of NAD+ precursor.
Quinolinic acid是一种内生性的神经毒素,活化N-methyl-D-aspartate接受器以及在生物合成NAD+的前驱物。
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They were two new compounds, [cyclo(Pro-Val-Phe-Phe-Pro-Val-Phe-Ser-Leu),7],[2-N-(1-methoxycarbonylethyl)guanosine, 10], and eight known compounds,(p-hydroxybenzoic acid, 1),(methyl succinate, 2),(russulaceramide, 3),(phenylalanine, 4),(guanine, 5),(β-carboline, 6),(uridine, 8), and (adenosine, 9). All the compounds were isolated from Amanita exitialis for the first time.
分别为:对羟基苯甲酸(p-hydroxybenzoic acid,1)、丁二酸二甲酯(methyl succinate,2)、神经酰胺(russulaceramide,3)、苯丙氨酸(phenylalanine,4)、鸟嘌呤核苷(guanine,5)、β-咔啉(β-carboline,6)、环(脯氨酸-缬氨酸-苯丙氨酸-苯丙氨酸-脯氨酸-缬氨酸-苯丙氨酸-丝氨酸-亮氨酸) [cyclo(Pro-Val-Phe-Phe-Pro-Val-Phe-Ser-Leu),7]、尿嘧啶核苷(uridine,8)、腺嘌呤核苷(adenosine,9)、2-N-(1-甲氧羰基乙基)鸟苷[2-N-(1-Methoxycarbonylethyl)guanosine, 10]。10个化合物均为首次从致命鹅膏中分离得到,其中化合物7和10为新化合物。
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Methods: The N-methyl-N-nitro-N-nitroso-guanidine transformed eternalized human gastric mucosa epithelium GES-1 cell line was used in vitro as a model of gastric precancerous lesion. The medicated canine serum was prepared by feeding to the adult Beagle dog with Radix notoginseng extracts and obtaining the serum after 2-hour medication. MC cells were cultured with medicated canine serum or non-medicated canine serum for 72 hours.
采用被N-甲基-N'-硝基-N-亚硝基胍(N-methyl-N'-nitroso-guanidine, MNNG)转化后的永生化人胃黏膜上皮细胞系GES-1细胞作为胃癌前病变细胞的体外研究模型,用三七提取物一次性灌胃彼格犬,取给药后2h的血清作为实验药物血清。
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Second, the solthe solthe sol-gel solution did not contain alcohol, instead, poly methyl methacrylate, aniline and phosphate salt(calcium phosphate dibasic, manganese phosphate or zinc phosphate) were added.
第二部分是在未加入酒精的状况下,将有机高分子聚甲基丙烯酸甲酯(poly methyl methacrylate, PMMA)加入含有磷酸盐(磷酸氢钙、磷酸锰或磷酸锌)的溶胶中,并利用苯胺的催化,得到奈米级的有机-无机复合皮膜。
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On the basis of the initial mechanism of deiodinase and the idea of hapten design derived from the method of"hydrophobic pocket modification", three haptens of thyroxine derivatives, o-methyl-〓, o-benzyl-〓 and o-p-nitro-benzyl-〓 with successively-raising hydrophobicity, were designed and synthesized, and their structures characterized.
以天然脱碘酶的初步催化机制和疏水腔修饰法的半抗原设计思想为依据,设计合成了三种疏水性不同的甲状腺素衍生物半抗原:o-methyl-〓,o-benzyl-〓和o-p-nitro-benzyl-〓,并对其结构进行了表征。
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Objective To explore the toxic effect of methyl tertiary butyl ether in brain, liver, lung and kidney of rats.
目的 研究甲基叔丁基醚(methyl tertlary butyl ether, MTBE)对大鼠肝、肺、肾、脑等组织器官的毒性作用。
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Objective To explore the toxic effects and mechanism of methyl tertiary-butyl ether in the brain tissues of fetal mice and pregnant mice.
目的:探讨甲基叔丁基醚(Methyl Tertiary Butyl Ether, MTBE)对孕鼠及其胎鼠脑组织的毒作用及分子机制。
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Benzene, toluene, ethylbenzene, xylenes isomers and methyl tert-butyl ether exist widely in the groundwater contaminated by gasoline.
中文摘要苯、甲苯、乙苯、对二甲苯与甲基第三丁基醚(methyl tert-butyl ether,简称MTBE)普遍存在汽油污染的地下水中。
- 推荐网络例句
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Now, however, all children continue in "comprehensive" schools, and the eleven-plus determines which courses of study the child will follow.
然而现在,所有的孩子都要在综合学校继续学习,所以这次考试只是决定他们将要学习哪些课程。
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Cultivatable land , and led to a general recognition that development must not be carried at the cost of agriculture .
城区的迅速扩大在很多情况下侵占了宝贵的可耕地,使人们普遍认识到发展不能以牺牲农业为代价。
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Detailed Intrinsic Reaction Coordination calculations were carried out to guarantee the optimized transition-state structures being connected to the related tautomers.
同时,做了详尽的内禀反应坐标计算,以保证所得到的过渡态连接相应的始末异构体。