查询词典 method of synthesis

In this paper, it is reported the synthesis of a new type of nanostructured film that is composed of needle-shaped TiO2 particles through an acetic acid modified sol-gel method.

使用醋酸修饰的溶胶－胶法制备了一种由针形颗粒构成的二氧化钛纳米薄膜。

Province, Shijiazhuang, Baoding have been involved in two rounds of 61 cities nationwide survey and synthesis of MSM epidemic prevention and control work, 4-6 months of this year the third round of the survey will be carried out; the rest of the city of nine work-site investigations and Shijiazhuang, Baoding, the third round of the survey the same time, also in accordance with the national program of 61 pilot cities, the survey used a snowball method, sample size of 300 people, mainly MSM population survey of AIDS, syphilis, hepatitis C infection; Shijiazhuang, Baoding, the completion of the third round of the national survey At the same time, will also focus on the MSM population in rural areas of the outbreak investigation; in July 2009, municipalities to carry out data entry, upload, analysis and summary.

我省石家庄、保定已参与两轮全国61个城市MSM疫情调查与综合防治工作，在今年4-6月份将开展第三轮调查；其余9市的现场调查工作与石家庄、保定的第三轮调查同步进行，同样按照国家61个试点城市方案、采用滚雪球法调查，样本量均为300人份，主要调查MSM人群艾滋病、梅毒、丙肝的感染情况；石家庄、保定在完成全国第三轮调查的同时，还将侧重于农村地区的MSM人群的疫情调查；2009年7月，各市进行数据录入、上传、分析和汇总。

The characteristics of quinazoline epidermal growth factor receptor inhibitors were briefly described in this paper, and the mechanism of receptor-tyrosine kinase inhibitor was also introduced. The synthesis of this kind of new compound was studied, and the synthetic route was redesigned and the method was modified.

本论文简述了受体酪氨酸激酶小分子抑制剂的发展概况，详细介绍了新型喹唑啉类表皮生长因子受体抑制剂，着重研究了该类化合物的合成，设计并打通了合成路线，同时又合成了25个新化合物。

It gives the more flexible method that valuates the trust degree and can more express the combination of the subjectivity and objectivity of trust to put the reputation concept into the synthesis of recommendatory trust and uses existing nodes as entities of saving reputation.

给出了更加灵活的计算直接信任度方法，并且将声誉引入推荐信任的合成中，利用现有的节点作为声誉存储实体，更加能够体现信任的主观性和客观性的结合。

During these years (1997-2000) in the research area of annonaceous acetogenins 5 natural products and a number of chiral-pure analogs of annonaceous acetogenins have been synthesized using sugars as the starting materials. Their high activity and selectivity against cell line of colon tumor and a relationship between activity and configuration have been found too. In the respect of inhibitor of sialidase two new methodologies for the synthesis of chiral-pure 3-deoxy-ulosonic acid using hetero-Diels-Alder reaction or asymmetric propargylation as the key reaction were developed. On the topic of anti-leukemia marine natural product clavulactone a synthetic method based on the free radical cyclization and starting from sugar has been developed. In other title of PKC inhibited agent sphingosine a new synthetic route with SN2' as the key reaction has also been disclosed.

项目期间（1997-2000）在番荔枝内酯方面从糖出发合成了五个天然产物和一批手性纯的类似物，它们对肠癌细胞有很高的活性和选择性，并与构型有关；在唾液酸酶抑制剂方面发展了二类全新手性纯高碳糖的合成方法－杂原子D－A反应或丙炔基不对称加成为关键的反应；抗白血病海洋天然产物群柱虫内酯方面研究了由糖出发和自由基环化反应的合成方法；对PKC 起抑制作用的鞘氨醇方面也开创了新的合成途径－由糖出发并以SN2'反应为关键反应。

The invention relates to the synthesis of N-aryl group-3-(4-Beta-D-pyran allose glycoside phenyl)-5-formyl isoxazole-4-formamide and discloses a helicid derivative which can improve the functions of a central nervous system and the preparation method thereof; wherein, the compound has good sedative, hypnotic and anti-convulsant effects and is taken in the 2000 edition Chinese Pharmacopoeia with the drug name of helicid tablets.

N-芳基-3-(4-β-D-吡喃阿洛糖苷苯基)-5-甲酰基异唑-4-甲酰胺的合成，发明公开了具有改善中枢神经系统功能的豆腐果苷类衍生物，及其制备方法。该类化合物具有良好的镇静、安眠、抗惊厥作用。目前已以药品名&神衰果素片&被收入2000年版《中国药典》。

Based on the synthesis method and the function of decreasing blood glucose levels of rosiglitazone, and the report on benzoquinones which resulted in a significant decrease in blood glucose levels, a novel non-thiazolidinedione class of PPARy agonist 2, 5-Dihydroxy-3-{4-[2-(methyl- pyridin-2- yl-amino)- ethoxy] -phenyl}-6-phenyl-[l, 4] benzoquinone (4) was designed and synthesized.

在合成罗格列酮的基础上，根据某些醌类结构化合物的类似胰岛素作用，设计并合成了一种非噻唑烷二酮类PPARγ激动剂2，5-二羟基3-{4-[2-(甲基-2-吡啶氨基)-乙氧基]-苯基}-6-苯基-1，4苯醌(4)。

The computational complexity has been reduced about 5 times over against the original one. Moreover, the interpolation and quantization processing of CW is more reasonable; 2. A secondary power normalization algorithm is proposed in this dissertation. This normalization algorithm ensures that the energy sum of SEW and REW is 1. So, the energy ratio of SEW and REW can be achieved only by using SEW energy. This ratio is applied in REW quantization and CW composition; 3. For more efficient quantization for Slowly Evolving Waveform magnitude, Rapidly Evolving Waveform magnitude and power parameters, firstly, by applying the Equivalent Rectangular Bandwidth theory, classifiable multi-codebooks method, analysis-by-synthesis approach and so on, a predictive AbS multi-codebooks SEW magnitude quantization scheme is proposed. In the scheme, pitch information is exploited to determine which codebook is searched; secondly, for REW magnitude quantization, this dissertation proposed a DCT-matrix multi-codebooks quantization scheme. The classification in muti-codebooks is based on pitch and quantized SEW power. The multi-codebooks structure may offer more the information in quantization and solve the problem of the bit requirement limits in quantization by consuming some extra storage space; Furthermore, for the switch quantization of CW gain, a new classified parameter is proposed.

本文的主要贡献体现为如下几方面：一、为了减少WI模型的计算复杂度，提出了基于快速傅立叶变换、三次B样条插值和周期延拓技术的特征波形(Characteristic Waveform，CW)表示和对齐的快速算法，与原方法相比，计算量下降到原方法的1/5，同时也使得CW在插值和量化时更合理；二、为了严格保证SEW与REW的能量和为1，提出了一种特征波形的二次功率归一化算法，仅需要SEW能量就可以算出二者的能量比，并可应用到后续的REW的分类量化和CW合成中；三、为了对慢渐变波形(Slowly Evolving Waveform，SEW)幅度、快渐变波形(Rapidly Evolving Waveform，REW)幅度和特征波形功率进行有效量化，本文首先采用临界频带理论、分析合成技术、感觉加权技术以及预测式矢量量化技术，提出了一种基于基音周期分类的SEW分析合成预测式多码书量化方法；其次，本文根据基音和量化后SEW的功率信息对REW幅度进行分类，提出了一种基于离散余弦变换的REW矩阵多码书量化方法。

Synthesis of Antidote of N-Dichloroacetyl-2-methyl-1-oxa-4-aza-spiro-4.4-nonane BI Hong-mei, ZHANG Jin-yan, LIANG Ying, SHEN Yong (College of Arts and Sciences Heilongjiang August First Reclamation University, Daqing 163319, Heilongjiang, China) Abstract: N-Dichloroacetyl-2-methyl-1-oxa-4-aza-spiro-4.4-nonane was synthesized by one pot method with isopropanolamine, cyclopentanone and dichloroacetyl chloride. The optimum reaction conditions obtained are as follows:the proportion in moles of the above materials is 1∶1∶1.2, reaction solvent is toluene, reaction temperature is -15 to -10 ℃,reaction time is 3 h, under the optimum condition, the yield of the compound is 50.0%.

除草剂解毒剂N-二氯乙酰基-2-甲基-1-氧杂-4-氮杂-螺[4.4]壬烷的合成毕洪梅，张金艳，梁英，沈勇(黑龙江八一农垦大学文理学院，黑龙江大庆 163319)摘要：以33%的氢氧化钠水溶液为缚酸剂，异丙醇胺、环戊酮和二氯乙酰氯为原料，采用&一锅法&合成了N-二氯乙酰基-2-甲基-1-氧杂-4-氮杂-螺[4.4]壬烷，采用正交实验法得到最佳反应条件：反应原料摩尔比为1∶1∶1.2，苯作溶剂，反应的温度为-15 ℃~-10 ℃，搅拌时间为3 h，产率达到50.0%。

The first part of this dissertation described a new effective method for asymmetric synthesis of,α,α-disubstituted amino acids from the asymmetric Strecker reaction products of aldehydes.

在本论文的第一部分，我们开发了一条以醛为原料，以不对称Strecker反应和不对称烷基化为关键步骤的合成α，α双取代氨基酸的有效方法，并对其立体选择性结果进行了机理探讨。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！