查询词典 metabolized

Borneol play a role in blood with an original form, benzyl cinnamate and benzyl bcnzoate were metabolized into 2-hydroxy-methyl benzoate to produce marked effect.

冰片以原型药物形式入血产生疗效，肉桂酸苄醋、苯甲酸苄酯被转为2-羟基苯甲酸甲酯的代谢产物发挥作用。

The aims of this study were:(1) to find methods to analyze 7-tocopherol and its metabolites;(2) to study the kinetics of 7-tocopherol metabolized in the S9 of male SD-rat liver in vitro;(3) to compare the differences of 7-tocopherol metabolized in the liver S9 of male SD-rat, male Brazil turtle and male cobia, respectively.

研究内容主要是：(1)γ-生育酚代谢物的分析方法；(2)γ-生育酚在雄性SD-大鼠肝S9的体外代谢动力学；(3)比较γ-生育酚在不同代谢水平动物的肝S9中代谢的差异。

Ethanol is metabolized by ADH, and NAD is used as a cofactor in its metabolism .

乙醇被ADH代谢分解，而NAD常被认为是代谢过程中的辅因子。

In these dogs the dose should be lowered or digitoxin should be used instead because it is metabolized and excreted through the liver.

这些狗的投药量必须被降低，或者使用通过肝脏代谢的洋地黄毒苷作为替代品。

The preliminary stiochiometric analysis showed that when the enzyme metabolized EDDA, two acetyl groups were removed and ethylenediamine and two glyoxylates were produced in the presence of oxygen.

然后对该酶促反应进行了定量分析：结果显示在IDA氧化酶的作用下每代谢一分子的EDDA将生成二分子的乙醛酸及一分子的乙二胺，同时也检测到过氧化氢的生成。

Even if the side effects are not drastic , the inactive enantiomer has to be metabolized and represents an unnecessary burden for the organism.

即使副作用不明显，引入无活性的对映体同样会造成机体代谢的负担。

The proportion of diseases and disease pattern are continuously transforming, which illustrated that prevalence of infectious diseases such as respiratory diseases kept decreasing, while the prevalence rate of circulatory system, endocrinopathy, nutritional and metabolized diseases were raising.

疾病构成分析结果表明，呼吸系统等感染性疾病的患病率持续下降，循环系统、内分泌、营养和代谢疾病患病率上升，疾病模式在进一步转变。

Drug-drug interactions easily occur for drugs metabolized via CYP3A isoenzyme under polypharmacy. Atorvastatin and simvastatin that are metabolized by CYP3A, are the two most frequently prescribed statins in our research. Around 40 % of interactions are difficult to detect due to patients' habits of doctor shopping.

经由CYP3A代谢的药品在多种药品同时并用下容易产生药品交互作用，本研究中使用率最高的atorvastatin及simvastatin，就是由CYP3A途径代谢，而研究中所有交互作用，有四成比例非由同一医师开出，这与病患到处就医习惯相关，使得医疗人员在交互作用的侦测上更加困难。

Itamin D from the skin and diet is metabolized in the lier to 25-hydroxyitamin D (Figure 1), which is used to determine a patient's itamin D status1,2,3,4; 25-hydroxyitamin D is metabolized in the kidneys by the enzyme 25-hydroxyitamin D-1-hydroxylase (CYP27B1) to its actie form, 1,25-dihydroxyitamin D.1,2,3,4 The renal production of 1,25-dihydroxyitamin D is tightly regulated by plasma parathyroid hormone leels and serum calcium and phosphorus leels.1,2,3,4 Fibroblast growth factor 23, secreted from the bone, causes the sodium–phosphate cotransporter to be internalized by the cells of the kidney and small intestine and also suppresses 1,25-dihydroxyitamin D synthesis.5 The efficiency of the absorption of renal calcium and of intestinal calcium and phosphorus is increased in the presence of 1,25-dihydroxyitamin D (Figure 1).2,3,6 It also induces the expression of the enzyme 25-hydroxyitamin D-24-hydroxylase (CYP24), which catabolizes both 25-hydroxyitamin D and 1,25-dihydroxyitamin D into biologically inactie, water-soluble calcitroic acid.2,3,4

从皮肤和食物来的维生素D在肝中代谢为25-羟基维生素D（图1），被用来决定病人体内维生素D情况的1，2，3，4；25-羟基维生素D在肾中被25-羟基维生素D1羟化酶（CYP27B1）转变为有活性的1，25-二羟基维生素D 。1，2，3，4由肾产生1，25-二羟基维生素D是被血浆甲状旁腺激素和血清钙，磷水平紧密调节。1，2，3，4由骨分泌的成纤维细胞生长因子23使钠磷协同转运蛋白被肾和小肠细胞内化及抑制1，25-二羟维生素D合成。5 在1，25-二羟基维生素D作用下肾和小肠吸收钙及磷的效率增高(图1)。2，3，6 它也包括25-羟四- 24 -羟化酶的表达(CYP24)，且将1，25二羟基维生素D和25羟基维生素D异化成无生物活性，水溶性的维生素D3-23羧酸。2，3，4

It is less important for drugs that are not metabolized by the kidney, but as a general rule we typically inject into the forelimbs unless you know for sure that the drug is not metabolized by the kidney.

对于那些不是通过肾脏代谢的药物这一点比较不重要，但是作为惯例我们通常是在前肢注射，除非你非常确定所使用的药物不是通过肾脏代谢的

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失