查询词典 metabolite

Immediately after its formation, this active metabolite is conjugated with glucuronic acidand then eliminated by the kidneys.

代谢产物形成后，此活性代谢物便立即与葡萄糖醛酸结合，然后8t t t8.com 由肾脏排出。

Immediately after its formation, this active metabolite is conjugated with glucuronic acidand then eliminated by the kidneys.65i

代谢产物形成后，此活性代谢物便立即与葡萄糖醛酸结合，然后由肾脏排出。65i

In the middle of 90's, it has been found that hydrogen sulfide (H2S) is one of the metabolite of aminothiopropionic acid, which might regulate the function of nervous system, especially hippocamp, and might regulation the tension of digestive tube and vascular, which has the similar biological function with NO and CO. Recently, major concern has emerged that H2S might be a novel endogenous agent during the patho-physiological reactions during endotoxic shock. Until now, the role of H2S playing in endotoxic shock is still quite confusing.

九十年代中叶，人们发现在体内半胱氨酸代谢过程中生成小分子气体硫化氢(hydrogen sulfide，H2S)，对神经系统特别是海马功能具有调节作用，且可以调节消化道和血管平滑肌张力，其生物学作用类似NO和CO.H2S作为内毒素休克时一系列病理生理反应中的一种新的内源性介质，已开始受到人们的重视。

Six experimental stages were designed in our procedure, those are:(1) metabolite recovery and tested sample preparation: the metabolites were recovered by Amberlite XAD-2 absorption, followed by MeOH elution and solvent concentration;(2) antioxidant detection and strain selection: samples were quantitatively analyzed by the inhibition effects on formation of lipid peroxides and TBARS to screen the strains able to produce antioxidants. According to the established screening methods, we chose out a strain of actinomycetes, designed as AMBL-029C;(3) antioxidant purification: the fermentation broth was recovered by a series of separation techniques including centrifugation, Amberlite XAD-2 absorption, followed by MeOH elution and a successive TLC purification. The resulting primary purified compound [temperately designed as AMBL-029C-TS] was further analyzed by HPLC to monitor its purity;(4) physical-chemical characteristics: judging from the acid-base fractionation experiments, and the pH and temperature stability tests, the compound was deduced to be a acidic compound with the properties of low polarity and highly pH and temperature stable;(5) mechanism of the antioxidant: in comparison with some other known antioxidants, TS was subjected to investigate its antioxidant mechanism, together with BHT,-tocopherol, as well as two streptomyces metabolites, homogentisic acid and -phenylpyruvic acid, which were previously isolated as the natural antioxidants in our laboratory.

针对本实验目的，我们设计了以下的实验步骤﹔（1）二次代谢物回收及检测样本处理：我们将发酵所得的培养上清液，利用疏水吸附性树酯Amberlite XAD-2吸附回收，并以甲醇溶离及真空减压浓缩脱水等方式处理，以取得提供抗氧化活性筛选之检测样本；（2）抗氧化活性检测及菌种筛选：以「过氧化脂质」和「硫丙二醯尿」的生成量进行定性定量分析以作为抗氧化物质生产菌筛选之用；经此筛选程序，我们选获了具有抗氧化物质高生产力的菌株，命名为AMBL-029C；（3）抗氧化物质的分离纯化：针对生产菌株的发酵回收处理液，以矽胶薄层色层分离法经物质层析纯化后，并以高效能液相层析法(High performance liquid chromatography；HPLC)分析物质可得一初级纯化物质，命名为AMBL-029C-TS；（4）抗氧化物质的物理化学性质分析：由酸碱转溶（acid-base fractionation）实验得知，此抗氧化物质属於中低极性的强酸性物质，对温度（37℃-100℃）及酸碱度（pH3.0-13.0）均表现出高稳定性；（5）在抗氧化机制探讨方面，我们针对数种不同的抗氧化机制进行探讨，即： 1。

To our knowledge, reverse phase of high performance liquid chromatography was firstly developed to analyze the metabolites of 7-tocopherol with ideal results. Meanwhile, Gas chromatography/Mass chromatography were used to analyze the structures of unknown metabolites of 7-tocopherol and a main unknown metabolite was identified as a side chain ω- hydroxylate of 7-tocopherol.The kinetic results of of 7-tocopherol reacted in the S9 of male SD-rat liver showed that the optimal time was 45 min; the optimal concentration of S9 5 mg/ml; the optimal concentration of NADPH 1 mM; and the optimal concentration of 7-tocopherol 8 μg/ml. The result of γ-tocopherol metabolized in the S9 of male SD-rat was the best; male Brazil turtle better; and male cobia worst.

本试验首次确立了γ-生育酚代谢物的RP-HPLC分析方法，结果理想且重现性好；用GC／MS对γ-生育酚的未知代谢物结构进行分析，判断其中一种主要的代谢物为γ-生育酚侧链初级羟基化代谢物；γ-生育酚在雄性SD-大鼠肝S9的代谢动力学表明，本实验条件下代谢反应的最佳时间为45min，S9浓度为5mg／ml，NADPH浓度为1mM，γ-生育酚浓度为8μg／ml；发现γ-生育酚在雄性SD-大鼠肝S9中代谢最高，雄性巴西龟次之，雄性军曹鱼最低。

KETO is a natural metabolite of DHEA that has all of the benefits but none of the side effects associated with DHEA.

它是一种天然的DHEA的代谢物，而且没有任何副作用。

The effects of several components in the culture medium on Lithospermum erythrorhizon cell growth and secondary metabolite synthesis were studied, as well as structural dynamic model. The two-liquid-phase culture of Lithospermum erythrorhizon was carried out by choosing the proper organic solvent as the second phase. The bioactive carrier for adsorption was prepared and the condition of cell immobilization was determined. We combined the technique of two-liquid-phase culture and immobilization to carry out the culture. We chose the suitable type of reactor, studied its characteristics and results of cell culture using this reactor. The fed-batch operation was also studied on the basis of twoliquid-phase culture and immobilization used in culture in the reactor.

本文研究了紫草细胞悬浮培养中培养基中多种成分对细胞生长与次生代谢产物合成的影响，进行了结构化的动力学模型研究；通过选择合适的有机溶剂对紫草细胞进行了双液相培养研究；通过确定以吸附为细胞的固定化方法，进行了生物活性吸附载体的制备与固定化细胞的制备研究；并结合双液相培养技术，对紫草细胞进行了固定化培养及其动力学模型的研究；对反应器进行选型，并进行冷模与热模研究；在反应器中进行了固定化紫草细胞的双液相培养条件下的流加操作研究。

ResultsBoth culture temperature and lumination braught about manifest effect on the induction of cell growth and secondary metabolite accumulation by oxalate.

结果光照和培养温度对草酸的诱导效果有很大影响，其中在12 h/d的光照下， 0.01～1 mmol·L-1的草酸对细胞生长和皂苷积累都有促进作用，而10 mmol·L-1的草酸对多糖积累有促进作用；在4个温度(22，24，26和28℃)水平下，随着培养温度的升高，添加草酸对细胞生长的抑制作用增强，但有利于多糖和皂苷的积累。

We also found an addiction metabolite (M5) of metformin with methylglyoxal in the perfused rat liver.

此外，我们并发现Metformin与内生性Methylglyoxal加合之代谢产物。

This information supports a reasonable probability that all monogastric species eliminate the originally ingested substance, melamine, or its analogues, and not a metabolite.

此信息支持一个合理的概率，所有单胃物种消除原先摄取物质，三聚氰胺，或其类似物，而不是一个代谢物。

I can still vividly recall the impressive scenes you gave. You were among my friends and relatives who accompanied me from my house to the seaport and when the porters were slow to show up, you obligingly carried my suitcase for me.

你对我的种种感人情意，使我记忆犹新，那天你随着我的亲友从家里送我上轮船，搬运工迟迟不来，你毅然替我提着皮箱上船。

St. Nicholas became the patron saint of Russia, where he was famous for his red cape, flowing white beard, and bishop's mitre.

圣尼古拉成了俄罗斯人的守护神，在那里，他以身披红斗篷，留着飘逸的白胡须，戴着主教法冠而闻名。